Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Subtype terms (29)
More specific conditions that are subtypes of Pain in the MeSH hierarchy.
- Abdominal Pain
99 drugs (59 approved, 40 experimental)
- Acute Pain
154 drugs (103 approved, 51 experimental)
- Arthralgia
74 drugs (36 approved, 38 experimental)
- Back Pain
159 drugs (98 approved, 61 experimental)
- Breakthrough Pain
16 drugs (12 approved, 4 experimental)
- Cancer Pain
47 drugs (35 approved, 12 experimental)
- Chest Pain
38 drugs (33 approved, 5 experimental)
- Chronic Pain
205 drugs (128 approved, 77 experimental)
- Earache
1 drug approved
- Eye Pain
8 drugs (7 approved, 1 experimental)
- Facial Pain
25 drugs (23 approved, 2 experimental)
- Flank Pain
8 drugs (7 approved, 1 experimental)
- Glossalgia
1 drug approved
- Headache
138 drugs (98 approved, 40 experimental)
- Intractable Pain
28 drugs (26 approved, 2 experimental)
- Labor Pain
49 drugs (37 approved, 12 experimental)
- Mastodynia
17 drugs (13 approved, 4 experimental)
- Metatarsalgia
- Musculoskeletal Pain
40 drugs (29 approved, 11 experimental)
- Neck Pain
38 drugs (29 approved, 9 experimental)
- Neuralgia
159 drugs (90 approved, 69 experimental)
- Nociceptive Pain
16 drugs (12 approved, 4 experimental)
- Nociplastic Pain
- Pain Threshold
7 drugs (3 approved, 4 experimental)
- Pelvic Pain
40 drugs (31 approved, 9 experimental)
- Postoperative Pain
273 drugs (169 approved, 104 experimental)
- Procedural Pain
28 drugs (21 approved, 7 experimental)
- Referred Pain
5 drugs (4 approved, 1 experimental)
- Renal Colic
42 drugs (32 approved, 10 experimental)
Drugs by status
Approved for this indication (129)
- nalbuphine
- levobupivacaine
- nefopam
- mefenamic acid
- pentazocine
- lornoxicam
- aceclofenac
- ropivacaine
- naproxen
- carisoprodol
- midazolam
- paeony glucosides
- sm-153
- benoxinate
- dezocine
- isoflurane
- cannabis
- rosehip
- naltrexone
- nitrous oxide
- orphenadrine hydrochloride
- dihydrocodeine
- nimesulide
- caffeine
- capsicum
- nitroglycerin
- diclofenac
- opium alkaloids
- prilocaine
- hydrocodone
- +99 more
Phase 4 trials (142)
- ondansetron
- pantoprazole
- flurbiprofen
- sertraline
- dextrose
- glucose
- epinephrine
- nitrogen
- melatonin
- moxifloxacin
- simvastatin
- inactivated influenza vaccine
- pentafluoropropane
- hyaluronidase (ovine)
- clonazepam
- varenicline
- nitric oxide
- lanolin
- onabotulinumtoxinA
- iodine
- venlafaxine
- oxygen
- fluocinonide
- platelet-rich plasma
- prednisolone
- agalsidase beta
- varicella zoster virus glycoprotein e antigen
- tromethamine
- levetiracetam
- esmolol
- +112 more
Phase 3 trials (104)
- clindamycin
- desipramine
- relugolix
- linzagolix
- treprostinil
- desvenlafaxine
- neridronic acid
- l-glutamine
- lactobacillus brevis
- salicylic acid
- glutathione
- taglidine
- cetylpyridinium chloride
- paclitaxel
- lenalidomide
- tetrodotoxin
- clobazam
- acetylcarnitine
- vitamin c
- capecitabine
- mr-107a-01
- carboplatin
- methocarbamol
- zicotinide
- benzhydrocodone
- ethinyl estradiol
- hsk16149
- cycloserine
- fulranumab
- valproic acid
- +74 more
Phase 2 trials (164)
Phase 1 trials (82)
- quercetin
- olp-1002
- sodium monododecyl sulfate
- fingolimod
- verapamil
- axomadol
- digoxin
- hrs-2129
- methylene blue
- gsk1482160
- mandarin oil
- cilostazol
- mannitol
- lavender
- sphenopalatine
- metformin
- abx-1431
- nicardipine
- mavatrep
- itraconazole
- melphalan
- askc200
- pf-04427429
- pf-06273340
- sbs-1000
- loperamide
- in1011-n17
- oxymetazoline
- anakinra
- ppc-5650
- +52 more
Other trials (136)
- tegafur
- tricaine
- exemestane
- potassium chloride
- atracurium
- polymethylmetacrylate
- acmella oleracea
- gamma-aminobutyric acid
- sogyeonghwalhyeol-tang
- topocaine
- corn
- ethyl vanillin
- liraglutide
- clove
- desogestrel
- turmeric
- lemongrass oil
- mineral oil
- tannic acid
- trichlorobutanol
- paraffin oil
- gimeracil
- cinnamaldehyde
- platelets
- cis-9-cetylmyristoleate
- chuna
- isobutamben
- metoprolol
- rose oil
- placental tissue extract
- +106 more
Organizations
Organization Involved with Phase 4 Indications (17)
- Ache Laboratorios Farmaceuticos S.A.
- Astellas
- Pfizer
- Analgesic Solutions
- Mallinckrodt
- University of Washington
- Ohio State University
- University of Southern Denmark
- University of Chicago
- OrthoCarolina Research Institute
- University of Maribor
- University of Perugia
- Charlotte Surgery Center an affiate of SCA
- Krka
- Instituto de Ciências Farmacêuticas (ICF)
- INTERBORA
- 3ARH
Organization Involved with Phase 3 Indications (19)
- Grunenthal
- Boehringer Ingelheim
- Hoosier Cancer Research Network
- Mahidol University
- Northwestern University
- University of Pavia
- University of California, San Francisco
- Thailand Research Fund
- University of Strasbourg
- Orebro University
- University of Sao Paulo
- University of Poitiers
- Navigant
- Government of France
- Air Liquide
- ViroMed
- Duta Wacana Christian University
- Helixmith Co., Ltd.
- PT SOHO Global Health Tbk
Organization Involved with Phase 2 Indications (39)
- AstraZeneca
- Biogen
- Novartis
- Allergan
- Angelini
- Arcion Therapeutics Inc
- BioChemics, Inc.
- BioDelivery Sciences International
- Centrexion Therapeutics
- Harrison Clinical Research
- Mundipharma
- Urigen
- Azad University
- Harvard University
- Sheffield Hallam University
- University of California, San Diego
- Glenmark Pharmaceuticals
- University of Minnesota
- Jehangir Clinical Development Centre Pvt. Ltd.
- Nerve & Muscle Center of Texas
- K.L.E.S Dr. Prabhakar Kore Hospital & Medical research Centre
- TOTALL Diabetes Hormone Institute
- Jnana Sanjeevani Medical Centre
- Getwell Hospital and Research Centre
- Bangalore Clinisearch
- Arthur Asirvathma Hospital
- NeuroHelp
- DADO Medical s.r.o
- Mitsubishi Tanabe
- Watson Pharmaceuticals
- +9 more
Organization Involved with Other Experimental Indications (6)