cannabis
Cannabis, commonly known as marijuana, weed, pot, and ganja, among other names, is a non-chemically uniform psychoactive drug from the Cannabis plant. Native to Central or South Asia, cannabis has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by smoking, vaporizing, within food, or as an extract. — Wikipedia
Clinical trial activity
229 trials · 177 clinical orgs · 0 marketing orgs
Earliest trial started Sep 1, 2001 (NCT00255580)
Timeline
Indications
Approved for
Studied for
- Acquired Immunodeficiency Syndrome · Phase 2
- Acute Pain · Phase 3
- Adolescent · Phase 2
- Affect · Phase 2
- Aging · Phase 2
- Alcohol Drinking · Phase 2
- Alcohol-Induced Disorders · Phase 1/Phase 2
- Alcoholism · Phase 2
- Alzheimer Disease · Phase 2
- Amyotrophic Lateral Sclerosis · Phase 2/Phase 3
- Analgesics, Opioid · Phase 4
- Anemia, Sickle Cell · Phase 2
- Anxiety · Phase 2
- Arthritis, Psoriatic · Phase 2
- Arthritis, Rheumatoid · Phase 2
- Attention Deficit and Disruptive Behavior Disorders · Phase 2
- Attention Deficit Disorder with Hyperactivity · Phase 2
- Autism Spectrum Disorder · Phase 3
- Autistic Disorder · Phase 2
- Automobile Driving · Phase 2
- Back Pain · Phase 3
- Bipolar Disorder · Phase 2
- Brachial Plexus Neuropathies · Phase 3
- Brain Injuries, Traumatic · Phase 3
- Breast Neoplasms · Phase 1
- Cancer Pain · Phase 1/Phase 2
- Cannabidiol · Phase 2
- Cannabinoids · Phase 2/Phase 3
- Cannabis · Phase 4
- Carcinoma · Phase 1
- Carcinoma, Hepatocellular · Phase 2
- Chronic Pain · Phase 3
- Chronic Traumatic Encephalopathy · Phase 2
- Cocaine-Related Disorders · Phase 4
- Cognitive Dysfunction · Phase 2
- Colitis, Ulcerative · Phase 2
- Colorectal Neoplasms · Phase 2
- Complex Regional Pain Syndromes · Phase 1
- Constipation · Phase 1
- Coronavirus · Phase 2
- Coronavirus Infections · Phase 2
- COVID-19 · Phase 2
- Crohn Disease · Phase 2
- Dementia · Phase 2/Phase 3
- Depression · Phase 2
- Diabetes Mellitus · Phase 3
- Diabetes Mellitus, Type 2 · Phase 3
- Diabetic Neuropathies · Phase 3
- Diagnosis · Phase 2
- Diagnosis, Dual (Psychiatry) · Phase 1
- Driving Under the Influence · Phase 1/Phase 2
- Dronabinol · Phase 2
- Drug Interactions · Phase 1
- Drug-Related Side Effects and Adverse Reactions · Phase 1/Phase 2
- Drug Resistant Epilepsy · Phase 3
- Dyspnea · Phase 2
- Electromyography · Phase 2/Phase 3
- Endometriosis · Phase 2/Phase 3
- Epilepsy · Phase 2
- Exercise · Phase 2
- Feeding and Eating Disorders · Phase 3
- Fibromyalgia · Phase 4
- Gastrointestinal Diseases · Phase 1
- Glaucoma · Phase 2
- Glioblastoma · Phase 1
- Health Services for the Aged · Phase 1
- Healthy Volunteers · Phase 1
- Heart Disease Risk Factors · Early Phase 1
- Hepatitis C · Phase 2
- Hidradenitis Suppurativa · Phase 2
- HIV · Phase 2
- HIV Infections · Phase 2
- Hyperalgesia · Phase 2
- Hypotension · Phase 1
- Inflammatory Bowel Diseases · Phase 2
- Low Back Pain · Phase 3
- Lung Neoplasms · Phase 1
- Major Depressive Disorder · Phase 2
- Marijuana Abuse · Phase 2
- Marijuana Smoking · Phase 2
- Marijuana Use · Phase 2
- Medical Oncology · Phase 2/Phase 3
- Migraine Disorders · Phase 2
- Motor Neuron Disease · Phase 2/Phase 3
- Mouth Neoplasms · Phase 1
- Multiple Sclerosis · Phase 3
- Muscle Spasticity · Phase 3
- Myofascial Pain Syndromes · Phase 2/Phase 3
- Nausea · Phase 2
- Neck Pain · Phase 3
- Neoplasms · Phase 3
- Neuralgia · Phase 3
- Neuralgia, Postherpetic · Phase 1/Phase 2
- Nicotine · Phase 1
- Obesity · Phase 2
- Obsessive-Compulsive Disorder · Phase 1/Phase 2
- Opiate Overdose · Phase 2
- Opioid-Related Disorders · Phase 2
- Osteoarthritis, Knee · Phase 2
- Pain · Phase 3
- Pain Threshold · Phase 2
- Palliative Care · Phase 2/Phase 3
- Pancreatic Neoplasms · Phase 2
- Paraplegia · Phase 3
- Parkinson Disease · Phase 2
- Pelvic Pain · Phase 2/Phase 3
- Peripheral Nerve Injuries · Phase 3
- Peripheral Nervous System Diseases · Phase 3
- Phantom Limb · Phase 3
- Pharmacokinetics · Phase 1
- Pharmacology · Phase 1
- Phobia, Social · Phase 2
- Postoperative Pain · Phase 3
- Protein-Energy Malnutrition · Phase 3
- Pruritus · Phase 3
- Psoriasis · Phase 1
- Psychiatry · Phase 1/Phase 2
- Psychotic Disorders · Phase 1
- Pulmonary Disease, Chronic Obstructive · Phase 2
- Quality of Life · Phase 2/Phase 3
- Reflex Sympathetic Dystrophy · Phase 1/Phase 2
- Renal Dialysis · Phase 3
- Reproductive Health · Phase 1
- Respiratory Insufficiency · Phase 4
- Restless Legs Syndrome · Phase 2
- Retinal Degeneration · Early Phase 1
- Retinitis Pigmentosa · Early Phase 1
- Rett Syndrome · Phase 1/Phase 2
- Safety · Phase 1
- Schizophrenia · Phase 1
- Sciatica · Phase 1/Phase 2
- Seizures · Phase 2
- Severe Acute Respiratory Syndrome · Phase 2
- Sleep Disorders, Intrinsic · Phase 2
- Sleep Initiation and Maintenance Disorders · Phase 2
- Sleep Wake Disorders · Phase 2
- Smoking · Early Phase 1
- Spinal Cord Diseases · Phase 2/Phase 3
- Spinal Cord Injuries · Phase 2/Phase 3
- Stress Disorders, Post-Traumatic · Phase 2
- Stroke · Phase 3
- Substance-Related Disorders · Phase 1
- Tachycardia · Phase 1
- Temporomandibular Joint Disorders · Phase 2/Phase 3
- Tinnitus · Phase 1
- Tobacco Use · Phase 2
- Tourette Syndrome · Phase 2
- Traumatology · Phase 3
- Vaping · Phase 2
- Vomiting · Phase 1/Phase 2
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCannabis (drug) ↗
- NCATSFTS5RM302N ↗
- WikipediaHash oil ↗
- WikipediaCannabis ↗
Also known as
- cannabis
- cannabis
- cannabis based medicine extract
- cannabis indica
- cannabis oil
- cannabis sativa extract
- gw-2000-02
- marijuana
- sativex
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07257939 | Phase 3 | Jul 1, 2026 | Fenix Innovation Group, Neurotech USA |
| NCT07257978 | Phase 2/Phase 3 (Phase 3) | Jul 1, 2026 | Fenix Innovation Group, Neurotech USA |
| NCT06956014 | Phase 3 | Mar 31, 2026 | Vertanical GmbH |
| NCT07224698 | Phase 2 | Feb 1, 2026 | Multidisciplinary Association for Psychedelic Studies |
| NCT07216690 | Phase 2 | Jan 5, 2026 | Johns Hopkins University, National Institute on Drug Abuse (NIDA) |
| NCT07214155 | Phase 1 | Jan 1, 2026 | Johns Hopkins University, National Institute on Drug Abuse (NIDA) |
| NCT07224932 | Phase 2 | Dec 19, 2025 | University of Colorado, Denver |
| NCT07105449 | N/A | Oct 1, 2025 | National Institute on Drug Abuse (NIDA), University of Toronto |
| NCT07091084 | N/A | Jul 15, 2025 | Memorial Sloan-Kettering Cancer Center |
| NCT06859710 | Phase 1 | Jun 1, 2025 | University of California, Los Angeles |
| NCT06755346 | Phase 1 | Apr 1, 2025 | Washington State University |
| NCT06863740 | N/A | Mar 31, 2025 | University of Toronto |
| NCT06334016 | Early Phase 1 (Phase 1) | Mar 27, 2025 | National Institute on Drug Abuse (NIDA), State University of New York, Buffalo |
| NCT06807762 | Phase 1 | Mar 10, 2025 | GreenCare Pharma |
| NCT06435299 | Phase 3 | Jan 1, 2025 | University of Western Brittany |
| NCT06351540 | Phase 1 | Jan 1, 2025 | Johns Hopkins University, National Institute on Drug Abuse (NIDA) |
| NCT06713447 | Phase 1 | Dec 1, 2024 | CMAX Clinical Research, Fenix Innovation Group, Neurotech USA |
| NCT06595576 | N/A | Oct 1, 2024 | University of Toronto |
| NCT06526208 | Phase 2 | Oct 1, 2024 | Southwest Autism Research & Resource Center |
| NCT06293040 | Phase 1 | Sep 26, 2024 | Johns Hopkins University, National Institute on Drug Abuse (NIDA) |
Organizations
Research & Development (177)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| National Institute on Drug Abuse (NIDA) | Government | 38 | 2 | 4 | 2004 |
| Columbia University | Academic/Hospital | 23 | 21 | 2 | 2004 |
| University of California, San Diego | Academic/Hospital | 20 | 19 | 4 | 2001 |
| Johns Hopkins University | Academic/Hospital | 15 | 15 | 2 | 2013 |
| University of Toronto | Academic/Hospital | 14 | 11 | 4 | 2018 |
| Apurano Pharmaceuticals GmbH | For profit | 8 | 8 | 1 | 2023 |
| Fenix Innovation Group | For profit | 7 | 7 | 3 | 2021 |
| Neurotech USA | For profit | 7 | 0 | 3 | 2021 |
| University of California, San Francisco | Academic/Hospital | 7 | 4 | 3 | 2002 |
| Yale University | Academic/Hospital | 7 | 5 | 3 | 2016 |
| Vertanical GmbH | For profit | 6 | 6 | 3 | 2021 |
| Technion University | Academic/Hospital | 5 | 2 | 3 | 2013 |
| University of California, Davis | Academic/Hospital | 5 | 2 | 2 | 2003 |
| University of Connecticut | Academic/Hospital | 5 | 2 | 3 | 2016 |
| University of Kentucky | Academic/Hospital | 5 | 5 | 2 | 2019 |
| Hebrew University | Academic/Hospital | 4 | 4 | 2 | 2017 |
| NHTSA | Government | 4 | 0 | 2 | 2012 |
| Research Foundation for Mental Hygiene, Inc. | Academic/Hospital | 4 | 0 | 1 | 2006 |
| Tel Aviv University | Academic/Hospital | 4 | 4 | 3 | 2010 |
| University of California, Los Angeles | Academic/Hospital | 4 | 4 | 1 | 2020 |