abx-1431
Small moleculeexperimental
Clinical trial activity
17 trials · 8 clinical orgs · 0 marketing orgs
Phase 1
16
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Nov 1, 2016 (NCT02875678)
Timeline
Indications
Studied for
- Diabetes Mellitus · Phase 1
- Dyspepsia · Phase 1
- Epilepsies, Partial · Phase 1
- Fibromyalgia · Phase 1
- Healthy Volunteers · Phase 1
- Multiple Sclerosis · Phase 1
- Myelitis · Phase 1
- Myelitis, Transverse · Phase 1
- Neuralgia, Postherpetic · Phase 1
- Neuromyelitis Optica · Phase 1
- Pain · Phase 1
- Small Fiber Neuropathy · Phase 1
- Spasm · Phase 1
- Stress Disorders, Post-Traumatic · Phase 1
- Tic Disorders · Phase 2
- Tourette Syndrome · Phase 2
- Traumatology · Phase 1
Mechanism of action
- Monoglyceride lipaseINHIBITOR
MGLL inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- abx-1431
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05219838 | Phase 1 | Jan 18, 2022 | Lundbeck |
| NCT05201092 | Phase 1 | Jan 5, 2022 | Lundbeck |
| NCT05177029 | Phase 1 | Nov 26, 2021 | Lundbeck |
| NCT05081518 | Phase 1 | Sep 29, 2021 | Lundbeck |
| NCT04990219 | Phase 1 | Sep 27, 2021 | Lundbeck |
| NCT05028673 | Phase 1 | Aug 23, 2021 | Lundbeck |
| NCT04974359 | Phase 1 | Jun 24, 2021 | Lundbeck |
| NCT04713254 | Phase 1 | Dec 8, 2020 | Lundbeck |
| NCT04597450 | Phase 1 | Sep 30, 2020 | Lundbeck |
| NCT04419636 | Phase 1 | May 29, 2020 | Lundbeck |
| NCT04405323 | Phase 1 | May 20, 2020 | Lundbeck |
| NCT03625453 | Phase 2 | Aug 31, 2018 | Abide Therapeutics, Bioanalytical Systems, Inc., CogState Ltd., FGK Clinical Research GmbH |
| NCT03447756 | Phase 1 | Oct 2, 2017 | Abide Therapeutics, ARENSIA EXPLORATORY MEDICINE |
| NCT03138421 | Phase 1 | May 1, 2017 | Abide Therapeutics, University of Liverpool, University of Oxford |
| NCT03058562 | Phase 1 | Feb 1, 2017 | Abide Therapeutics |
| NCT02929264 | Phase 1 | Dec 1, 2016 | Abide Therapeutics, University of Oxford |
| NCT02875678 | Phase 1 | Nov 1, 2016 | Abide Therapeutics |
Showing 17 of 17 trials
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Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Lundbeck | For profit | 11 | 11 | 1 | 2020 |
| Abide Therapeutics | For profit | 6 | 6 | 2 | 2016 |
| University of Oxford | Academic/Hospital | 2 | 0 | 1 | 2016 |
| ARENSIA EXPLORATORY MEDICINE | For profit | 1 | 0 | 1 | 2017 |
| Bioanalytical Systems, Inc. | For profit | 1 | 0 | 1 | 2018 |
| CogState Ltd. | For profit | 1 | 0 | 1 | 2018 |
| FGK Clinical Research GmbH | For profit | 1 | 0 | 1 | 2018 |
| University of Liverpool | Academic/Hospital | 1 | 0 | 1 | 2017 |
8 organizations
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