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Diarrhea
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
Subtype terms (1)
More specific conditions that are subtypes of Diarrhea in the MeSH hierarchy.
- Diarrhea, Infantile
6 drugs experimental
Drugs by status
Approved for this indication (33)
- barberry
- bismuth subsalicylate
- crofelemer
- diosmectite
- fidaxomicin
- furazolidone
- ginger
- simethicone
- bovine colostrum
- nitazoxanide
- saccharomyces boulardii
- Racecadotril
- rifamycin
- rifaximin
- sulfamethoxazole
- vancomycin
- bifidobacterium breve
- bifidobacterium longum
- bilberry
- montmorillonite
- streptococcus faecium
- lactobacillus sporogenes
- asesculus
- clinoptilolite
- kaolin, light
- sodium bicarbonate
- difenoxin
- diphenoxylate
- telotristat ethyl
- sulphaphthalyl
- +3 more
Phase 4 trials (35)
- metronidazole
- iron
- albendazole
- procaine benzylpenicillin
- bifidobacterium animalis
- colesevelam
- clavulanate
- heweizhixie
- amoxicillin
- ursodeoxycholic acid
- octreotide
- atorvastatin
- rotavirus vaccine, live, oral, pentavalent
- ceftriaxone
- ciprofloxacin
- ondansetron
- autologous microbiome
- bacillus licheniformis
- lactobacillus plantarum
- zinc dichloride
- azithromycin
- amino acids
- Streptococcus thermophilus
- corn
- rabies vaccine adsorbed
- trimethoprim
- vitamin a
- methylfolate
- human rotavirus, live attenuated
- lactobacillus casei
- +5 more
Phase 3 trials (47)
- levofloxacin
- calcium carbonate
- bacille calmette-guerin
- bacillus clausii
- bovine lactoferrin
- irinotecan
- egg
- eluxadoline
- entoban
- l-glutamine
- glycine
- mesalamine
- sodium polystyrene sulfonate
- tolevamer
- rifampin
- inulin
- lactobacillus gasseri
- lamivudine
- lysozyme
- pentosan polysulfate sodium
- lactose
- lanreotide
- lactoferrin
- sulfasalazine
- bifidobacterium infantis
- bifidobacterium bifidum
- Tetanus and diphtheria toxoids adsorbed
- killed enterotoxigenic escherichia coli vaccine
- fructo-oligosaccharide
- killed oral cholera vaccine
- +17 more
Phase 2 trials (61)
- obeticholic acid
- maltodextrin
- ace527
- phy906
- choleragarde
- prednisone
- elsiglutide
- fiber
- folic acid
- fluorouracil
- heat-labile enterotoxin of e. coli
- calcium
- cyanocobalamin
- imm-124e
- DTaP, inactivated poliovirus, haemophilus influenzae b conjugate, hepatitis b vaccine
- iowh032
- kefir
- leucovorin
- tropifexor
- vitamin c
- beta-glucans
- ops-2071
- cow milk
- colchicine
- phosphatidylcholine
- typhoid vi polysaccharide vaccine
- Isatuximab
- cyclophosphamide
- streptomycin
- cabazitaxel
- +31 more
Phase 1 trials (29)
- ach04
- cefixime
- diethylhomospermine
- dolutegravir
- celecoxib
- temozolomide
- danshen
- rfla-mbp
- shigella conjugate vaccines
- shigella flexneri 2a invaplex 50
- anti-cfa/i bovine igg
- anti-cfae bovine igg
- oxaliplatin
- hydrochlorothiazide
- mirtazapine
- mecs6
- r192g
- simeprevir
- cefpodoxime
- mosapride
- water
- ferrous sulfate
- detoxified shigella flexneri 2a artificial invasin complex
- ser-155
- dwj1230
- ft1
- lmn-401
- venbeta6890
- kan-004
Other trials (41)
- vitamin d3
- sucrose
- raloxifene
- pancrelipase
- gentian root
- gastropylor complex
- florestor
- tigecycline
- citrulline
- bifidus regularis
- niacin
- tinidazole
- human milk
- infloran
- sunitinib
- xiaochaihu-tang
- thiamine
- capecitabine
- boswellia serrata
- e. coli strain e1392-75-2a
- l-epigallocatechin
- lactoflorene colesterolo
- osmolite
- bacillus subtilis
- zind
- pyridoxine
- bivalent oral polio vaccine (bopv), type 1 and type 3
- sodium dichloroisocyanurate
- doxepin
- lysine
- +11 more
Organizations
Organization Involved with Phase 4 Indications (111)
- McMaster University
- Astellas
- Isfahan University
- Kaohsiung Medical University
- Canadian International Development Agency
- Napo Pharmaceuticals
- Namik Kemal University
- IQVIA
- Pierre and Marie Curie University
- University of Maryland
- Kenya Medical Research Institute
- University of Milan
- Sisli Hamidiye Etfal Training and Research Hospital
- Shanghai University
- National Autonomous University of Mexico
- Princeton University
- Johns Hopkins University
- National Yang-Ming University
- Athena Institute, Netherlands
- National Institute for Health Research, United Kingdom
- Duke University
- Instituto de Investigacion de las Alteraciones del Crecimiento, Desarrollo y Enfermedades Metabolicas
- University of Nottingham
- Tufts University
- Ross University School of Veterinary Medicine
- Okmeydani Hospital Istanbul
- Tillotts Pharma
- Ho Chi Minh City University of Medicine and Pharmacy
- University of Texas at Houston
- Cu Chi Health Department
- +81 more
Organization Involved with Phase 3 Indications (151)
- Laval University
- University of Gothenburg
- University of Toronto
- Wirghtington Wigan and Leigh NHS Trust
- Actavis
- University of Zurich
- Indian Council of Medical Research
- Technion University
- Muhimbili University
- University of London
- AGI Therapeutics, Inc.
- Emory University
- immunova
- Sandoz
- Barnsley Hospital NHS Foundation Trust
- University of Alberta
- University of Birmingham
- National Institute of Cholera and Enteric Diseases, Kolkata, India
- Yeshiva University
- University of Science Malaysia
- Radiation Therapy Oncology Group
- Federal University of Bahia
- University of South Florida
- University of Southern Denmark
- National Institute for Medical Research, Tanzania
- Ventria Bioscience
- Temple University
- Cairo University
- University of Bristol
- Women and Children's Health Research Institute (WCHRI)
- +121 more
Organization Involved with Phase 2 Indications (105)
- Universidad del Valle de Guatemala
- University of Kansas
- Sykehuset Innlandet HF
- Entera Health, Inc
- Society for Essential Health Action and Training, New Delhi, India
- Jean Brown Research
- Wroclaw Medical University
- University of Caen-Normandie
- Georgetown University
- Government of Thailand
- Drais Pharmaceuticals, Inc.
- Revogenex, Inc.
- MRA Clinical Research
- Omnifarma Kiev LLC
- Imperial College London
- Inveresk Research
- Biose
- Summit Therapeutics
- Yonsei University
- Genentech
- Advanced Biomedical Research
- Metropolitan Gastroenterology Group PC, Chevy Chase Clinical Research
- University of Helsinki
- University of Wisconsin
- Bristol-Myers Squibb
- PhytoCeutica
- Hillel Yaffe Medical Center
- Sun Yat-Sen University
- United Medix Laboratories Ltd.
- University of Minnesota
- +75 more
Organization Involved with Phase 1 Indications (14)
- State University of New York, Buffalo
- Bio-Kinetic Clinical Applications
- St. Jude Children's Hospital
- Prolacta Bioscience
- Janssen Pharmaceutica NV
- Baylor University
- TriHealth
- Hamilton Health Sciences Corporation
- Huazhong University of Science and Technology
- Rhone-Poulenc Rorer
- Ache Laboratorios Farmaceuticos S.A.
- Guangzhou University
- National Center for Complementary and Integrative Health (NCCIH)
- Pennsylvania State University
Organization Involved with Other Experimental Indications (52)
- Makassed General Hospital
- Michigan State University
- PanTheryx, Inc.
- Government of Zanzibar
- Augusta University
- Civil Hospital, Hyderabad, Pakistan
- University of Connecticut
- United States Department of Agriculture
- Therabel Pharma SA/NV
- Government of Pakistan
- University of Duisburg-Essen
- National Institute of Public Health, Lao PDR
- Nil Ratan Sircar Medical College and Hospital
- Money, Mary E., M.D.
- Nestle
- New York Medical College
- Micronutrient Initiative
- City of Hope National Medical Center
- Seed Health
- University of Indonesia
- NIZO Food Research
- LiveLeaf Inc.
- Catholic University of Sacred Heart, Rome
- Hormozgan University of Medical Sciences
- European and Developing Countries Clinical Trials Partnership (EDCTP)
- United Nations
- Case Western Reserve University
- Northwestern University
- Winclove Bio Industries BV
- Wageningen University
- +22 more