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beta-glucans

Botanicalexperimental

Pleuran is an insoluble polysaccharide, isolated from Pleurotus ostreatus. — Wikipedia

Clinical trial activity

101 trials · 128 clinical orgs · 0 marketing orgs

Phase 1
19
Phase 2
32
Phase 3
9
Phase 4
3

Earliest trial started Nov 1, 2001 (NCT00037011)

Timeline

2000s

  1. Jan 1, 2001

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2003

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2007

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • beta-d-glucan
  • beta-d-glucan
  • beta glucan
  • beta glucan
  • beta-glucan
  • beta-glucan
  • beta-glucans
  • beta-glucans
  • high molecular weight oat beta-glucan
  • imprime pgg
  • low molecular weight beta-glucan
  • low molecular weight oat beta-glucan
  • medium molecular weight oat beta-glucan

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07305259Early Phase 1 (Phase 1)Nov 12, 2025Florida State University
NCT07199764Phase 2Oct 31, 2025Lustgarten Foundation, University of Pennsylvania
NCT07082439Phase 2Sep 10, 2025Merck, University of Pennsylvania
NCT07104929Phase 2Aug 31, 2025Ovation Fertility
NCT07085858N/AJul 25, 2025LanZhou University
NCT06861062N/AApr 8, 2025Huazhong University of Science and Technology
NCT06629805N/AAug 1, 2024Pusan National University
NCT06151782N/ADec 1, 2023University of Oslo
NCT06057948Phase 2Sep 21, 2023Memorial Sloan-Kettering Cancer Center
NCT05465798Phase 2Jun 30, 2023Concentra, Hospital Geriátrico Paz de La Tarde, Hospital Gustavo Fricke, Wohlstand Pharmaceutical
NCT06083350N/AJun 27, 2023Huazhong University of Science and Technology
NCT05981404N/AMay 26, 2023University of Glasgow
NCT06987396N/AMay 15, 2023Vitae Health Innovation
NCT05524688Phase 1/Phase 2 (Phase 2)Jan 31, 2023Lallemand SAS, University of Florida
NCT05484011Phase 1Dec 31, 2022Celldex Therapeutics, HiberCell, Inc., University of Pennsylvania
NCT05364736N/AOct 17, 2022Sun Yat-Sen University
NCT05074303Phase 1Aug 1, 2022Danstar Ferment AG, University of Florida
NCT05029427N/AJan 7, 2022Agriculture and Agri-Food Canada, University of Manitoba
NCT05177172N/ADec 1, 2021Lund University
NCT05159778Phase 2Nov 9, 2021HiberCell, Inc., Merck, Stony Brook University
Showing 20 of 101 trials
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Organizations

Research & Development (128)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
BiotheraFor profit11832005
Biotec Pharmacon ASAFor profit8832003
National Cancer Institute (NCI)Government6022001
Agriculture and Agri-Food CanadaGovernment5022008
MerckFor profit5012016
Cornell UniversityAcademic/Hospital4422001
University of ManitobaAcademic/Hospital4412010
HiberCell, Inc.For profit3322021
Huazhong University of Science and TechnologyAcademic/Hospital3312018
University of BergenAcademic/Hospital3222006
University of CopenhagenAcademic/Hospital3212009
University of LouisvilleAcademic/Hospital3122006
University of OsloAcademic/Hospital3122007
University of PennsylvaniaAcademic/Hospital3222022
Elegant And Olive Health Clinic, CanadaAcademic/Hospital2012018
Humber River HospitalAcademic/Hospital2012018
James Graham Brown Cancer CenterAcademic/Hospital2222006
Memorial Sloan-Kettering Cancer CenterAcademic/Hospital2212021
National Taiwan UniversityAcademic/Hospital2212011
Nofima Mat ASFor profit2012016
128 organizations
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