montmorillonite

Botanicalexperimental

Montmorillonite is a very soft phyllosilicate group of minerals that form when they precipitate from water solution as microscopic crystals, known as clay. It is named after Montmorillon in France. Montmorillonite, a member of the smectite group, is a 2:1 clay, meaning that it has two tetrahedral sheets of silica sandwiching a central octahedral sheet of alumina. The particles are plate-shaped with an average diameter around 1 μm and a thickness of 0.96 nm; magnification of about 25,000 times, using an electron microscope, is required to resolve individual clay particles. Members of this group include saponite, nontronite, beidellite, and hectorite. — Wikipedia

Clinical trial activity

4 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
1
Phase 2
0
Phase 3
1
Phase 4
1

Earliest trial started Jun 1, 2013 (NCT02124330)

Timeline

2020s

  1. Jan 1, 2020

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2022

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • montmorillonite
  • montmorillonite

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05252546Phase 1Mar 8, 2022Hengrui Therapeutics, Inc.
NCT04736186Phase 2/Phase 3 (Phase 3)May 16, 2020Tianjin Medical University
NCT04479202Phase 4Feb 8, 2020Chinese Medical Association, Nanjing University
NCT02124330N/AJun 1, 2013IRCCS Burlo Garofolo, University of Trieste
Showing 4 of 4 trials
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Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Chinese Medical AssociationAcademic/Hospital1112020
Hengrui Therapeutics, Inc.For profit1112022
IRCCS Burlo GarofoloAcademic/Hospital1112013
Nanjing UniversityAcademic/Hospital1012020
Tianjin Medical UniversityAcademic/Hospital1112020
University of TriesteAcademic/Hospital1012013
6 organizations
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