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Streptococcus thermophilus

Cell therapyexperimental

Streptococcus thermophilus formerly known as Streptococcus salivarius subsp. thermophilus is a gram-positive bacterium, and a fermentative facultative anaerobe, of the viridans group. It tests negative for cytochrome, oxidase, and catalase, and positive for alpha-hemolytic activity. It is non-motile and does not form endospores. S. thermophilus is fimbriated. — Wikipedia

Clinical trial activity

41 trials · 56 clinical orgs · 0 marketing orgs

Phase 1
9
Phase 2
11
Phase 3
3
Phase 4
8

Earliest trial started Feb 1, 2006 (NCT00587041)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2013

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2014

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • microbiotaTissue restoration

    microbiota tissue restoration

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • s. thermophilus
  • streptococcus thermophillus
  • streptococcus thermophilus

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06125626Phase 2Jul 10, 2023University of Palermo
NCT07296718Phase 4May 15, 2023Islamia University of Bahawalpur
NCT05767450N/ADec 16, 2022Vita-Salute University of Milano. Italy
NCT04997057N/ASep 15, 2021CEN Biotech, Hopital Antoine Beclere, Pileje
NCT04988594N/AFeb 1, 2021Faculty of Medical Science, Paraguay, Faculty of Medical Sciences, Clinical Hospital, Universidad de Cordoba
NCT04769687Phase 2Nov 21, 2020University of Franche-Comté
NCT04787419N/ASep 1, 2020University of Indonesia
NCT04366089Phase 2Mar 26, 2020University of Roma La Sapienza
NCT04065503Early Phase 1 (Phase 1)Sep 30, 2019Lallemand SAS, University of Florida
NCT04160767Phase 4Jan 30, 2019University of Milan
NCT03801655N/AAug 15, 2018University of Oxford
NCT03511365Phase 1/Phase 2 (Phase 2)May 15, 2018Northwell Health
NCT03840538Phase 1/Phase 2 (Phase 2)Jan 1, 2018Cairo University
NCT03341403Phase 2/Phase 3 (Phase 3)Jan 17, 2017European Union, University of Liege
NCT02795845N/ANov 1, 2016Emek Medical Center
NCT03051425N/AMar 28, 2016Yonsei University
NCT02640625Phase 1/Phase 2 (Phase 2)Jan 1, 2016Osaka University, University of Oslo
NCT02518295N/ASep 30, 2015Nestle
NCT01970683Phase 3Aug 1, 2014Catholic Health Initiatives
NCT02276326N/AJul 1, 2014University of Roma La Sapienza
Showing 20 of 41 trials
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Organizations

Research & Development (56)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
University of MilanAcademic/Hospital3312010
University of Roma La SapienzaAcademic/Hospital3222014
National Center for Complementary and Integrative Health (NCCIH)Government2012006
National Institutes of Health (NIH)Government2022006
NestleFor profit2222009
Agroscope Liebefeld-Posieux Research Station ALPAcademic/Hospital1012014
Bambino Gesù Hospital and Research InstituteAcademic/Hospital1112012
Bright Dairy & Food Co., LtdFor profit1112013
Cairo UniversityAcademic/Hospital1112018
Catholic Health InitiativesAcademic/Hospital1112014
CEN BiotechFor profit1112021
Centro Pediatrico Albina de PatinoAcademic/Hospital1112011
Charles UniversityAcademic/Hospital1112014
Children's Medical Center of DaytonAcademic/Hospital1012008
Dayton Children's HospitalAcademic/Hospital1112008
Emek Medical CenterAcademic/Hospital1112016
European UnionGovernment1012017
Faculty of Medical Science, ParaguayAcademic/Hospital1012021
Faculty of Medical Sciences, Clinical HospitalAcademic/Hospital1112021
Govind Ballabh Pant Institute of Postgraduate Medical Education and ResearchAcademic/Hospital1112008
56 organizations
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