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fructo-oligosaccharide

Botanicalexperimental

Fructooligosaccharides (FOS) also sometimes called oligofructose or oligofructan, are oligosaccharide fructans, used as an alternative sweetener. FOS exhibits sweetness levels between 30 and 50 percent of sugar in commercially prepared syrups. It occurs naturally, and its commercial use emerged in the 1980s in response to demand for healthier and calorie-reduced foods. — Wikipedia

Clinical trial activity

28 trials · 44 clinical orgs · 0 marketing orgs

Phase 1
7
Phase 2
6
Phase 3
3
Phase 4
0

Earliest trial started Jun 1, 2005 (NCT01549782)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2008

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • fructooligosaccharide
  • fructooligosaccharide
  • fructo-oligosaccharide
  • fructooligosaccharides
  • fructooligosaccharides
  • fructo-oligosaccharides
  • idolax
  • raftilose p95
  • short-chain fructo-oligosaccharides

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07202481N/AOct 31, 2025Federal University of Minas Gerais
NCT05480696Phase 1Sep 30, 2022Canadian Institutes of Health Research (CIHR), McMaster University
NCT05485402N/ASep 1, 2022Rovira i Virgili University
NCT05420805N/AApr 1, 2022Azienda Ospedaliera Universitaria Senese, University of Milan
NCT05207488N/AOct 1, 2021University of Illinois
NCT04499183N/AOct 8, 2020Wageningen University
NCT04013607N/AJul 31, 2019University of Groningen, Wageningen University
NCT05073029N/AFeb 10, 2019Bogomolets National Medical University, Taras Shevchenko National University of Kyiv
NCT03495401N/AApr 28, 2018Gadjah Mada University
NCT04551937N/AFeb 14, 2018University of Illinois, University of Illinois at Chicago
NCT03474276Phase 3Jan 31, 2018Action Contre la Faim, Centre de Recherches Médicales et Sanitaires, Niger, Institut Pasteur
NCT03049631N/AMay 18, 2017Illinois Institute of Technology
NCT04525040N/ASep 14, 2016Bogomolets National Medical University, Lallemand SAS
NCT02805075Phase 1Jun 30, 2016National Cancer Institute (NCI), Stanford University
NCT02364869N/AMay 1, 2015Universidade Federal do Parana, University of Sao Paulo
NCT03035981N/AAug 31, 2014Purdue University
NCT02203955Phase 1Aug 1, 2014Mayo Clinic
NCT02140749N/AApr 1, 2014Ingredion Incorporated, NIZO Food Research
NCT01847950N/ANov 1, 2012Hospital Avicenne, Tereos
NCT01414517Phase 3Aug 1, 2010University of London
Showing 20 of 28 trials
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Organizations

Research & Development (44)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Bogomolets National Medical UniversityAcademic/Hospital2112016
Mayo ClinicAcademic/Hospital2222006
National Center for Complementary and Integrative Health (NCCIH)Government2012006
Purdue UniversityAcademic/Hospital2222009
TereosFor profit2212009
University of IllinoisAcademic/Hospital2212018
Wageningen UniversityAcademic/Hospital2212019
AbbottFor profit1012009
Action Contre la FaimAcademic/Hospital1012018
Azienda Ospedaliera Universitaria SeneseAcademic/Hospital1112022
Ben Gurion UniversityAcademic/Hospital1112008
Canadian Institutes of Health Research (CIHR)Academic/Hospital1012022
Centre de Recherches Médicales et Sanitaires, NigerAcademic/Hospital1012018
Federal University of Minas GeraisAcademic/Hospital1112025
Gadjah Mada UniversityAcademic/Hospital1112018
Gastroenterology Associates of Central GeorgiaAcademic/Hospital1012006
GTC NutritionFor profit1012009
Hospital AvicenneAcademic/Hospital1012012
Hospital General Universitario Gregorio MarañonAcademic/Hospital1112005
Illinois Institute of TechnologyAcademic/Hospital1112017
44 organizations
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