diosmectite

Trade name: Smecta

Small moleculeexperimental

Diosmectite is a natural silicate of aluminium and magnesium used as an intestinal adsorbent in the treatment of several gastrointestinal diseases, including infectious and non-infectious acute and chronic diarrhoea, including irritable bowel syndrome diarrhea subtype. Other uses include: chronic diarrhea caused by radiation-induced, chemotherapy-induced, and HIV/AIDS-associated chronic diarrhea. — Wikipedia

Clinical trial activity

9 trials · 7 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
4
Phase 3
3
Phase 4
3

Earliest trial started Jan 1, 2005 (NCT00276328)

Timeline

2000s

  1. Jan 1, 2006

    Earliest Phase 3 Sponsor(trial)

2010s

  1. Jan 1, 2014

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2016

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • diosmectite
  • diosmectite
  • smectite

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06588036Early Phase 1 (Phase 1)Sep 15, 2024Pakistan Army, Saglik Bilimleri Universitesi
NCT04788485Phase 4Sep 1, 2017Ain Shams University
NCT03045926Phase 1Aug 1, 2016Ipsen
NCT02704091Phase 4Mar 1, 2016Ipsen
NCT02354768Phase 3Oct 1, 2015Ipsen, University of Strasbourg
NCT02323516Phase 2Dec 1, 2014Ligue contre le cancer, France, University of Caen-Normandie
NCT00352989Phase 3Jul 1, 2006Ipsen
NCT00352716Phase 3Jun 1, 2006Ipsen
NCT00276328Phase 4Jan 1, 2005Ipsen
Showing 9 of 9 trials
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Organizations

Research & Development (7)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
IpsenFor profit6532005
Ain Shams UniversityAcademic/Hospital1112017
Ligue contre le cancer, FranceAcademic/Hospital1012014
Pakistan ArmyGovernment1112024
Saglik Bilimleri UniversitesiAcademic/Hospital1012024
University of Caen-NormandieAcademic/Hospital1112014
University of StrasbourgAcademic/Hospital1112015
7 organizations
Page 1 / 1