Liver Diseases
Pathological processes of the LIVER.
Subtype terms (24)
More specific conditions that are subtypes of Liver Diseases in the MeSH hierarchy.
- alpha 1-Antitrypsin Deficiency
36 drugs (14 approved, 22 experimental)
- Budd-Chiari Syndrome
- Chemical and Drug Induced Liver Injury
44 drugs (34 approved, 10 experimental)
- Cholestasis, Intrahepatic
11 drugs (8 approved, 3 experimental)
- Fatty Liver
150 drugs (65 approved, 85 experimental)
- Focal Nodular Hyperplasia
1 drug experimental
- Hepatic Infarction
- Hepatic Insufficiency
74 drugs (47 approved, 27 experimental)
- Hepatic Veno-Occlusive Disease
3 drugs approved
- Hepatitis
51 drugs (33 approved, 18 experimental)
- Hepatolenticular Degeneration
23 drugs (11 approved, 12 experimental)
- Hepatomegaly
7 drugs (6 approved, 1 experimental)
- Hepatopulmonary Syndrome
6 drugs approved
- Hepatorenal Syndrome
12 drugs (9 approved, 3 experimental)
- Hypertension, Portal
77 drugs (49 approved, 28 experimental)
- Liver Abscess
6 drugs approved
- Liver Cirrhosis
328 drugs (199 approved, 129 experimental)
- Liver Diseases, Alcoholic
26 drugs (11 approved, 15 experimental)
- Liver Diseases, Parasitic
- Liver Neoplasms
456 drugs (185 approved, 271 experimental)
- Peliosis Hepatis
- Porphyrias, Hepatic
1 drug approved
- Tuberculosis, Hepatic
- Zellweger Syndrome
7 drugs (6 approved, 1 experimental)
Drugs by status
Approved for this indication (20)
- l-cysteine
- sulfur hexafluoride lipid-type a microspheres
- shen pu yang gan wan
- entecavir
- iodipamide meglumine
- gadoxetate disodium
- moringa
- avatrombopag
- tricholine citrate
- cholic acid
- metreleptin
- tenofovir
- Biphenyl Dimethyl Dicarboxylate
- moringa oleifera
- Lusutrombopag
- Silibinin
- hemin
- technetium tc-99m pyro/trimeta phosphates kit
- thioctic acid
- fuzheng huayu
Phase 4 trials (74)
- tacrolimus
- hepatitis b vaccine (recombinant)
- ropivacaine
- dexmedetomidine
- cow milk
- conjugated linoleic acid
- midazolam
- human factor ix complex (prothrombin complex concentrate)
- tenofovir alafenamide
- silymarin
- s-methionine
- magnesium isoglycyrrhizinate
- dapagliflozin
- oxygen
- nitrous oxide
- deferiprone
- propofol
- anidulafungin
- spironolactone
- stavudine
- empagliflozin
- bupropion
- human fibrin
- henagliflozin
- vitamin e
- pioglitazone
- glucagon
- selenium
- promethazine hydrochloride
- lamivudine
- +44 more
Phase 3 trials (49)
- vir-2218
- vir-3434
- gabexate
- sirolimus
- urea
- candesartan
- tirzepatide
- Iomeprol
- Ursodoxicoltaurine
- octreotide
- alanine
- Galactose
- sorafenib
- lanreotide
- sevoflurane
- indocyanine green
- gabapentin
- eltrombopag
- tafamidis
- ramipril
- oblimersen sodium
- turmeric
- sufentanil
- fludeoxyglucose f-18
- aramchol
- choline
- bulevirtide
- fibrinogen (human)
- Octafluoropropane
- pentoxifylline
- +19 more
Phase 2 trials (72)
- alisporivir
- acamprosate
- lactobacillus rhamnosus
- icosapent ethyl
- diphenhydramine
- fomepizole
- ornithine
- mt2004
- Selpercatinib
- leucovorin
- perflutren protein-type a microspheres
- qel-001
- maralixibat
- rtx001
- nnc0194-0499
- revefenacin
- simeprevir
- betamethasone
- allopurinol
- atorvastatin
- autologous cd34+ cells
- oxaliplatin
- bismuth
- hepatitis c immune globulin
- ritonavir
- emricasan
- gimeracil
- erlotinib
- pemvidutide
- zinc sulfate
- +42 more
Phase 1 trials (307)
- ivacaftor
- methylnaltrexone
- biotin
- glasdegib
- azd4831
- y-3
- Balcinrenone
- inavolisib
- esketamine
- brincidofovir
- azd2693
- kp-001
- nemtabrutinib
- Remibrutinib
- gdc-6036
- aumolertinib
- aro-aat
- pf-05221304
- remimazolam
- xoma 358
- vadadustat
- toreforant
- dabrafenib
- binimetinib
- mirdametinib
- enasidenib
- abiraterone
- pevonedistat
- fevipiprant
- Vemircopan
- +277 more
Other trials (50)
- ethanol
- umbilical cord mesenchymal stem cells
- rituximab
- venofundin
- midodrine
- ginseng
- selenomethionine se-75
- maltodextrin
- cocoa bean
- amino acids
- propionibacterium freudenreichii
- ornithine aspartate
- Lactobacillus acidophilus
- sivelestat
- acitretin
- ajwa date
- bifidobacterium animalis
- sea water
- tramadol
- acetaminophen
- ibandronate
- cysteamine
- sintilimab
- acetobacter
- urotensin ii
- albumin (Human)
- calcium
- ketorolac
- soybean oil
- defibrotide
- +20 more
Organizations
Organization Involved with Phase 4 Indications (152)
- University of South Carolina
- Bristol-Myers Squibb
- Johns Hopkins University
- Cornell University
- Medical University of South Carolina
- Erasmus University Rotterdam
- Korea University
- German Center for Diabetes Research
- University of Padua
- Roche
- Soonchunhyang University
- University Hospital, Rijeka
- University of Missouri
- Apotex
- University of Chicago
- University of London
- University of Naples Frederico II
- University of Padova
- Harvard University
- University of Nebraska
- Government of Germany
- Medical College of Wisconsin
- Merck
- Clinical Hospital Centre Rijek, Croatia
- Katholieke Universiteit Leuven
- Duke University
- Vanderbilt University
- National University of Ireland
- Mercy Medical Center
- PharmaKing
- +122 more
Organization Involved with Phase 3 Indications (75)
- Sanofi
- Indian Council of Medical Research
- Ain Shams University
- National Heart, Lung, and Blood Institute (NHLBI)
- Institute of Liver and Biliary Sciences, India
- Eisai
- Cirius Therapeutics, Inc.
- Exalenz Bioscience LTD.
- Hebrew University
- ASPEN Rhoads Research Foundation
- University of Edinburgh
- University of Geneva
- Command Hospital, India
- University of Calgary
- PPD
- National Center for Research Resources (NCRR)
- Changi General Hospital
- University of British Columbia
- Beijing Trendful Kangjian Medical Information Consulting Limited Company
- University of Picardie Jules Verne
- University of Toronto
- Virginia Commonwealth University
- Gottfried Wilhelm Leibniz Universität Hannover
- German Liver Foundation
- Fresenius
- Kunming Medical University
- National University of Singapore
- Nycomed
- University of California, Davis
- University of Alberta
- +45 more
Organization Involved with Phase 2 Indications (167)
- Veterans Medical Research Foundation
- Loma Linda University
- Uppsala University
- Tobira Therapeutics, Inc.
- Jiangsu Nhwa Pharmaceutical Co., Ltd.
- Eli Lilly
- Northwell Health
- Shire
- Wenzhou Medical University
- Grupo Mexicano para el Estudios de las Enfermedades Hepaticas
- Memorial Sloan-Kettering Cancer Center
- Thomas Jefferson University
- Queen Elizaberth Hospital, Sabah
- Galmed Pharmaceuticals Ltd
- Government of Russia
- Viking Therapeutics, Inc.
- St. Petersburg State Public Medical Institution
- Pediatric Municipal Hospital of Rzeszow, Poland
- University of Birmingham
- Immuron Ltd.
- Lumena Pharmaceuticals
- Military Medical Academy named after SM Kirov, the Russian Ministry of Defense, Hospital Therapeutic Department and Clinic
- University of Kentucky
- TaiGen Biotechnology Co., Ltd.
- Amarnath, Rathna, M.D.
- Chiltern International
- Guerbet
- Hillel Yaffe Medical Center
- University of Western Ontario
- Nova Laboratories Limited
- +137 more
Organization Involved with Phase 1 Indications (120)
- ObsEva SA
- Genentech
- Daiichi Sankyo
- Sungkyunkwan University
- Gachon University
- Trevi Therapeutics
- NicOx
- Chong Kun Dang Pharmaceutical
- Inno.N
- Ohio State University
- Vanda Pharmaceuticals
- Marathon Pharmaceuticals
- Newron Pharmaceuticals
- Takeda
- Acerta Pharma
- Ochsner Health System
- Covance
- Array BioPharma
- Boryung Pharmaceutical Company
- Nektar Therapeutics
- Government of Malaysia
- Kadmon
- Harokopio University
- CohBar, Inc.
- Melinta Therapeutics
- Sponsor GmbH
- Tesaro
- Viriom
- Ono Pharmaceuticals
- Autonomous University of Madrid
- +90 more
Organization Involved with Other Experimental Indications (66)
- Federal University of Health Science of Porto Alegre
- Children's Medical Center Dallas
- Government of Mexico
- Biovil Research Group, LLC
- American College of Gastroenterology
- Federal University of Bahia
- Instituto Mexicano del Seguro Social
- Laval University
- Wyeth
- Government of Denmark
- Magna Graecia University
- Saarland University
- St. Luke's Health System, Boise, Idaho
- Bogomolets National Medical University
- Chinese University of Hong Kong
- National Natural Science Foundation of China
- Department of Veteran Affairs
- Daiwa Pharmaceutical Corporation
- Canadian Institutes of Health Research (CIHR)
- University of Paris
- University of Tennessee
- Jinlin University
- China Medical University
- Doctors Hospital at Renaissance
- Danish Council for Independent Research
- BASF
- Children's Hospital Los Angeles
- Wiener Wissenschafts-, Forschungs- und Technologiefonds
- Medanta - The Medicity
- Sir Salimullah Medical College
- +36 more