thioctic acid
Small moleculeexperimental
Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries. Lipoate is the conjugate base of lipoic acid, and the most prevalent form of LA under physiological conditions. Only the (R)-(+)-enantiomer (RLA) exists in nature. RLA is an essential cofactor of many processes. — Wikipedia
Clinical trial activity
5 trials · 11 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
3
Phase 3
2
Phase 4
1
Earliest trial started Aug 1, 2009 (NCT01258699)
Timeline
Indications
Approved for
Mechanism of action
- Unspecified targetAntioxidant
antioxidant
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaLipoic acid ↗
Also known as
- bk-c-0701
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06253429 | Phase 3 | Jan 1, 2023 | Ain Shams University |
| NCT03257514 | Phase 2 | Jun 1, 2017 | Ain Shams University |
| NCT03914404 | Phase 4 | Jan 26, 2016 | Catholic University of Korea, Chonbuk National University, Daegu Catholic University, Dongguk University, Gachon University, Inje University, Pusan National University, Soon Chun Hyang University, Yonsei University |
| NCT01261143 | Phase 3 | Aug 1, 2010 | Bukwang Pharmaceutical |
| NCT01258699 | Phase 1 | Aug 1, 2009 | Bukwang Pharmaceutical |
Showing 5 of 5 trials
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Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Ain Shams University | Academic/Hospital | 2 | 2 | 2 | 2017 |
| Bukwang Pharmaceutical | For profit | 2 | 2 | 2 | 2009 |
| Catholic University of Korea | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Chonbuk National University | Academic/Hospital | 1 | 1 | 1 | 2016 |
| Daegu Catholic University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Dongguk University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Gachon University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Inje University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Pusan National University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Soon Chun Hyang University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Yonsei University | Academic/Hospital | 1 | 0 | 1 | 2016 |
11 organizations
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