CDEK
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gdc-6036

Small moleculeexperimental

Clinical trial activity

8 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
6
Phase 2
3
Phase 3
2
Phase 4
0

Earliest trial started Jul 29, 2020 (NCT04449874)

Timeline

2020s

  1. Jan 1, 2020

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2024

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

C=CC(=O)N1CCN(c2nc(OC[C@@H]3CCCN3C)nc3c(F)c(-c4nc(N)cc(C)c4C(F)(F)F)c(Cl)cc23)[C@@H](C)C1
Mol. weight
622.07 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06793215Phase 3May 1, 2025Chugai, Roche
NCT06835465Phase 1Feb 21, 2025Genentech
NCT06734208Phase 1Dec 23, 2024Genentech
NCT06690138Phase 1Nov 15, 2024Genentech
NCT06677957Phase 1Nov 6, 2024Genentech
NCT06497556Phase 3Sep 23, 2024Chugai, Roche
NCT05789082Phase 1/Phase 2 (Phase 2)Jun 20, 2023Roche
NCT04449874Phase 1Jul 29, 2020Genentech, Roche
Showing 8 of 8 trials
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Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
GenentechFor profit5512020
RocheFor profit4332020
ChugaiFor profit2012024
3 organizations
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