CDEK
← All drugs Report issue

selenium

Small moleculeapproved

Approved

May 17, 1951

Selenium sulfide, an anti-infective agent, relieves itching and flaking of the scalp and removes the dry, scaly particles that are commonly referred to as dandruff or seborrhea. It is also used to treat tinea versicolor, a fungal infection of the skin. Topical selenium sulfide can be added to the therapeutic armamentarium for congenital or acquired hyperkeratosis. — NCATS

Clinical trial activity

114 trials · 179 clinical orgs · 12 marketing orgs

Phase 1
15
Phase 2
48
Phase 3
31
Phase 4
12

Earliest trial started Mar 31, 1991 (NCT02066610)

Timeline

1950s

  1. May 17, 1951

    Chattem — Earliest FDA Approval

  2. May 17, 1951

    Chattem — NDA Organization

  3. May 17, 1951

    Chattem — NDA Secondary Org

1970s

  1. Jan 21, 1974

    Allergan — Marketing Organization

  2. May 14, 1975

    Actavis — Marketing Organization

1980s

  1. Jul 3, 1980

    Ivax — Marketing Organization

  2. Nov 4, 1981

    ACP Nimble — Marketing Organization

  3. Nov 4, 1981

    Cosette — Marketing Organization

  4. Nov 4, 1981

    G & W Laboratories Inc. — Marketing Organization

  5. Sep 1, 1983

    Wockhardt — Marketing Organization

  6. Sep 1, 1983

    Xttrium Laboratories — Marketing Organization

1990s

  1. Jan 10, 1991

    Padagis Us — Marketing Organization

  2. Jan 10, 1991

    Perrigo — Marketing Organization

  3. Jan 1, 1999

    Earliest Phase 1 Sponsor(trial)

2000s

  1. Jan 1, 2000

    Earliest Phase 3 Sponsor(trial)

  2. Jan 1, 2002

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

Approval history

  • approvedMay 17, 1951

Chemistry & pharmacology

Loading structure…

SMILES

S=[Se]=S
Mol. weight
143.09 g/mol
Lipinski Ro5
Pass
Rule of 3
Yes
Chirality
Achiral Molecule
Inorganic
Yes
Polymer
No
Availability
Discontinued

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • abbottselsun
  • bioselenium
  • caspiselenio
  • disodium selenite
  • ellsurex
  • exsel
  • exsel
  • exsel
  • glo-sel
  • head & shoulders
  • head & shoulders
  • iosel-250
  • lenium
  • lenium
  • lenium
  • neoselen
  • pyrithione zinc
  • pyrithione zinc
  • pyrithione zinc
  • pyrithione zinc
  • pyrithione zinc
  • pyrithione zinc
  • ross brand 1 of selenium disulfide
  • ross brand 2 of selenium disulfide
  • ross brand 3 of selenium disulfide
  • selamin
  • selen
  • selen
  • selenii disulfidum
  • selenii disulfidum
  • selenio
  • selenio
  • selenium
  • selenium
  • selenium
  • sélénium
  • sélénium
  • selenium disulfide
  • selenium disulfide
  • selenium disulfide
  • selenium disulfide
  • selenium disulphide
  • selenium disulphide
  • selenium elemental
  • selenium elemental
  • selenium, elemental
  • selenium, elemental
  • selenium(iv) disulfide
  • selenium(iv) disulfide
  • selenium(iv) disulphide
  • selenium(iv) disulphide
  • selenium(iv) sulfide
  • selenium(iv) sulfide
  • selenium(iv) sulphide
  • selenium(iv) sulphide
  • selenium metallicum
  • selenium metallicum
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide
  • selenium sulfide, micronized
  • selenium sulfide, micronized
  • selenium sulfide (ses2)
  • selenium sulphide
  • selenium sulphide
  • selenium sulphide, micronized
  • selenium sulphide, micronized
  • selsun
  • selsun
  • selsun
  • selsun
  • selsun blue
  • selukos
  • selun gold
  • sodium selenite
  • sodium selenite
  • sodium selenite
  • sodium selenite
  • sodium selenite
  • sodium selenite
  • sodium selenium oxide
  • versel

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06694727Phase 3Feb 1, 2025Pharma Nord, University of Copenhagen
NCT06736015N/AOct 23, 2024ISTITUTO REGINA ELENA
NCT06362005Phase 4Oct 1, 2024Al Azhar University, Sphinx university
NCT06413043N/AMay 6, 2024All India Institute of Medical Sciences
NCT06951282Phase 1/Phase 2 (Phase 2)May 2, 2024Ain Shams University
NCT06117436Phase 2/Phase 3 (Phase 3)Oct 19, 2023Ain Shams University, Future University in Egypt
NCT05672095Phase 1/Phase 2 (Phase 2)Aug 18, 2023City of Hope National Medical Center, National Cancer Institute (NCI)
NCT05823337N/AJul 1, 2023Istanbul Medipol University
NCT05814874N/AApr 30, 2023Friedrich Schiller University
NCT07180329N/AFeb 1, 2023University of Health Sciences Lahore
NCT05472753N/ANov 16, 2022Government of Spain, University of Malaga
NCT07013890Phase 4Nov 2, 2022University of Turin
NCT05503706N/ASep 30, 2022L'Oreal
NCT05500742N/AAug 31, 2022University of Bologna
NCT06087068Phase 2Aug 1, 2022Chinese Academy of Medical Sciences
NCT04946123N/AJul 5, 2021Lo.Li. Pharma, Ltd.
NCT04835259N/AApr 30, 2021Sohag University
NCT05218577N/AJan 1, 2021Cairo University
NCT04662242Phase 4Dec 31, 2020Chang Gung University
NCT04005222Early Phase 1 (Phase 1)Sep 30, 2020Beytepe Murat Erdi Eker State Hospital
Showing 20 of 114 trials
Page 1 / 6

Organizations

Research & Development (179)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Cancer Institute (NCI)Government12132000
Ain Shams UniversityAcademic/Hospital4432013
BiosynFor profit4022009
Isfahan UniversityAcademic/Hospital4422011
Southwest Oncology GroupAcademic/Hospital4312000
University of TorontoAcademic/Hospital4322001
Cairo UniversityAcademic/Hospital3322013
Chinese Academy of Medical SciencesAcademic/Hospital3322018
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Government3011998
National Institutes of Health (NIH)Government3132006
Pharma NordFor profit3022003
Vanderbilt UniversityAcademic/Hospital3311998
Canadian Cancer Trials GroupAcademic/Hospital2012000
Cancer and Leukemia Group B (CALGB)Academic/Hospital2012000
City of Hope National Medical CenterAcademic/Hospital2222006
Friedrich Schiller UniversityAcademic/Hospital2122009
Harvard UniversityAcademic/Hospital2012001
Karolinska InstituteAcademic/Hospital2212007
Mayo ClinicAcademic/Hospital2012000
McMaster UniversityAcademic/Hospital2022000
179 organizations
Page 1 / 9

Marketing (13)

OrganizationOrg typeRelationshipDate
ACP NimbleFor profitMKTGNov 4, 1981
ActavisFor profitMKTGMay 14, 1975
AllerganFor profitMKTGJan 21, 1974
ChattemFor profitNDAMay 17, 1951
ChattemFor profitNDA2May 17, 1951
CosetteFor profitMKTGNov 4, 1981
G & W Laboratories Inc.For profitMKTGNov 4, 1981
IvaxFor profitMKTGJul 3, 1980
Padagis UsFor profitMKTGJan 10, 1991
PerrigoFor profitMKTGJan 10, 1991
Warner ChilcottFor profitNDA2—
WockhardtFor profitMKTGSep 1, 1983
Xttrium LaboratoriesFor profitMKTGSep 1, 1983