alanine
Alanine, or α-alanine, is an α-amino acid that is used in the biosynthesis of proteins. It contains an amine group and a carboxylic acid group, both attached to the central carbon atom which also carries a methyl group side chain. Consequently it is classified as a non-polar, aliphatic α-amino acid. Under biological conditions, it exists in its zwitterionic form with its amine group protonated and its carboxyl group deprotonated. It is non-essential to humans as it can be synthesized metabolically and does not need to be present in the diet. It is encoded by all codons starting with GC. — Wikipedia
Clinical trial activity
10 trials · 8 clinical orgs · 0 marketing orgs
Earliest trial started Jan 7, 2014 (NCT04022434)
Timeline
Indications
Mechanism of action
- alanineSupplementation
alanine supplementation
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaAlanine ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06881472 | N/A | Jan 1, 2025 | University of Copenhagen |
| NCT06579391 | N/A | Sep 30, 2024 | University of California, Irvine |
| NCT06419686 | Phase 1 | Jan 1, 2024 | University of Copenhagen |
| NCT04740580 | Early Phase 1 (Phase 1) | Jul 1, 2021 | Baylor University, The University of Texas, Dallas |
| NCT05076318 | N/A | Mar 1, 2021 | Aarhus University |
| NCT04703036 | Early Phase 1 (Phase 1) | Jan 11, 2021 | Baylor University |
| NCT04119843 | Phase 3 | Nov 30, 2019 | Ascelia Pharma AB, Humboldt University |
| NCT03566524 | N/A | Jul 1, 2018 | Baylor University |
| NCT03493178 | Early Phase 1 (Phase 1) | Apr 14, 2018 | Baylor University, The University of Texas, Dallas |
| NCT04022434 | N/A | Jan 7, 2014 | Augusta University |
Organizations
Research & Development (8)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Baylor University | Academic/Hospital | 4 | 4 | 2 | 2018 |
| The University of Texas, Dallas | Academic/Hospital | 2 | 0 | 1 | 2018 |
| University of Copenhagen | Academic/Hospital | 2 | 2 | 2 | 2024 |
| Aarhus University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Ascelia Pharma AB | For profit | 1 | 1 | 1 | 2019 |
| Augusta University | Academic/Hospital | 1 | 1 | 1 | 2014 |
| Humboldt University | Academic/Hospital | 1 | 0 | 1 | 2019 |
| University of California, Irvine | Academic/Hospital | 1 | 1 | 1 | 2024 |