Lactobacillus acidophilus
Cell therapyexperimental
The Lavochkin La-5 was a Soviet fighter aircraft of World War II. It was a development and refinement of the LaGG-3, replacing the earlier model's inline engine with the much more powerful Shvetsov ASh-82 radial engine. During its time in service, it was one of the Soviet Air Force's most capable types of warplane, able to fight German designs on almost equal footing. — Wikipedia
Clinical trial activity
196 trials · 238 clinical orgs · 0 marketing orgs
Phase 1
17
Phase 2
52
Phase 3
28
Phase 4
24
Earliest trial started Feb 12, 2001 (NCT00011141)
Timeline
Indications
Approved for
Studied for
- Abdominal Injuries · Phase 2/Phase 3
- Abdominal Pain · Phase 3
- Acute-On-Chronic Liver Failure · Phase 2/Phase 3
- Adenomatous Polyposis Coli · Phase 2
- Ascites · Phase 2
- Asthma · Phase 2/Phase 3
- Basal Ganglia Diseases · Phase 4
- Brain Diseases · Phase 4
- Candidiasis, Vulvovaginal · Phase 4
- Carcinoma, Transitional Cell · Phase 4
- Celiac Disease · Phase 4
- Central Nervous System Diseases · Phase 4
- Clostridium Infections · Phase 3
- Colic · Phase 4
- Colitis, Ulcerative · Phase 1
- Colonic Diseases, Functional · Phase 1/Phase 2
- Communicable Diseases · Phase 2
- Constipation · Phase 3
- Coronavirus Infections · Phase 2
- COVID-19 · Phase 2
- Crohn Disease · Phase 4
- Defecation · Phase 2/Phase 3
- Deglutition Disorders · Early Phase 1
- Diabetes Mellitus, Type 1 · Phase 4
- Diabetes Mellitus, Type 2 · Phase 4
- Diarrhea · Phase 3
- Digestive System Diseases · Phase 1/Phase 2
- Drug-Related Side Effects and Adverse Reactions · Phase 3
- Drug Resistance, Bacterial · Phase 2
- Dyspepsia · Phase 2/Phase 3
- Fatty Liver · Phase 1
- Helicobacter pylori · Phase 4
- Hepatic Encephalopathy · Phase 3
- Hirschsprung Disease · Phase 2
- Hyperoxaluria · Phase 1/Phase 2
- Hypertension · Early Phase 1
- Inflammatory Bowel Diseases · Phase 3
- Insulin Resistance · Phase 1/Phase 2
- Interleukin-17 · Phase 1/Phase 2
- Intestinal Neoplasms · Phase 2/Phase 3
- Irritable Bowel Syndrome · Phase 4
- Klebsiella pneumoniae · Phase 1/Phase 2
- Live Birth · Phase 2
- Liver Cirrhosis · Phase 2/Phase 3
- Lower Urinary Tract Symptoms · Phase 2
- Lupus Erythematosus, Systemic · Phase 2
- Menopause · Phase 2
- Metabolic Syndrome · Phase 4
- Movement Disorders · Phase 4
- Mucositis · Phase 3
- Neonatal Sepsis · Phase 3
- Neoplasms · Phase 3
- Nephrolithiasis · Phase 1/Phase 2
- Nervous System Diseases · Phase 4
- Neurodegenerative Diseases · Phase 4
- Non-alcoholic Fatty Liver Disease · Phase 1/Phase 2
- Osteoporosis · Phase 2
- Parkinson Disease · Phase 4
- Parkinsonian Disorders · Phase 4
- Peritonitis · Phase 2/Phase 3
- Pneumonia, Viral · Phase 2
- Polycystic Ovary Syndrome · Phase 3
- Pregnancy · Phase 4
- Probiotics · Phase 4
- Quality of Life · Phase 3
- Recurrence · Phase 4
- Respiratory Tract Infections · Phase 2
- Rhinitis, Allergic · Phase 4
- Rhinitis, Allergic, Seasonal · Phase 3
- Scleroderma, Systemic · Phase 4
- Sjogren's Syndrome · Phase 1/Phase 2
- Stomatitis · Phase 2
- Urinary Tract Infections · Phase 4
- Vaginosis, Bacterial · Phase 4
- Weight Gain · Phase 3
Mechanism of action
- microbiotaTissue restoration
microbiota tissue restoration
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaLavochkin La-5 ↗
- NCATS1PRR1V42V5 ↗
- WikipediaLactobacillus acidophilus ↗
- WikipediaLactobacillus ↗
- WikipediaLactic acid bacteria ↗
Also known as
- acidophilus
- kyodophilus
- kyo-dophilus
- la-5
- l. acidophilus
- l. acidophilus dds-1
- lacteol
- lactibiane
- lactibiane candisis
- lactic acid bacteria
- lactobacilli
- lactobacillus
- lactobacillus
- lactobacillus acidophilus boucardii
- lactobacillus acidophilus cl1285
- lactobacillus acidophilus l-92
- lactobacillus acidophilus la-5
- lactobacillus acidophilus lac-361
- lactobacillus acidophilus nas
- lactobacillus acidophilus ncfm
- lactobacillus acidophilus w37
- lactobacillus acidophilus w55
- lactobacillus cd 2
- tyndallized l. acidophilus
- vsl #3
- vsl#3
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06772090 | N/A | Dec 25, 2025 | University of Minnesota |
| NCT07276009 | N/A | Dec 1, 2025 | Nordic Bioscience |
| NCT07186465 | Phase 4 | Sep 11, 2025 | Mahidol University |
| NCT07165457 | N/A | Sep 4, 2025 | Clinica Universidad de Navarra |
| NCT07157462 | N/A | Sep 1, 2025 | Alyatec, Winclove Bio Industries BV |
| NCT07081100 | N/A | Aug 5, 2025 | Wecare Probiotics Co., Ltd. |
| NCT06906068 | N/A | Jun 2, 2025 | Laval University, St. Justine's Hospital, University of Ottawa |
| NCT06936137 | Phase 3 | Apr 20, 2025 | Ain Shams University |
| NCT06873438 | N/A | Mar 10, 2025 | Wecare Probiotics Co., Ltd. |
| NCT06643299 | Phase 2 | Dec 31, 2024 | Rush University |
| NCT06754228 | N/A | Nov 13, 2024 | Natural Immune Systems Inc |
| NCT06470906 | N/A | Aug 14, 2024 | Columbia University |
| NCT06899620 | N/A | Jul 1, 2024 | Wecare Probiotics Co., Ltd. |
| NCT06629441 | N/A | Jun 20, 2024 | Wecare Probiotics Co., Ltd. |
| NCT06607562 | N/A | Jun 3, 2024 | Wecare Probiotics Co., Ltd. |
| NCT07072871 | N/A | Apr 1, 2024 | PT Royal Medikalink Pharmalab |
| NCT06871540 | N/A | Oct 1, 2023 | Inonu University |
| NCT06616168 | Phase 1 | Sep 1, 2023 | Lviv National Medical University |
| NCT06125626 | Phase 2 | Jul 10, 2023 | University of Palermo |
| NCT05749081 | Phase 4 | Apr 30, 2023 | Nanchang University |
Showing 20 of 196 trials
Page 1 / 10
Organizations
Research & Development (238)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| VSL Pharmaceuticals | For profit | 7 | 3 | 4 | 2004 |
| Danisco | For profit | 5 | 3 | 3 | 2005 |
| Wecare Probiotics Co., Ltd. | For profit | 5 | 5 | 1 | 2024 |
| All India Institute of Medical Sciences | Academic/Hospital | 4 | 3 | 2 | 2007 |
| Bio-K Plus International Inc. | For profit | 4 | 4 | 2 | 2006 |
| Biosearch S.A. | For profit | 4 | 4 | 2 | 2016 |
| Bogomolets National Medical University | Academic/Hospital | 4 | 4 | 1 | 2015 |
| Chinese Academy of Medical Sciences | Academic/Hospital | 4 | 4 | 4 | 2019 |
| Jiao Tong University | Academic/Hospital | 4 | 1 | 2 | 2011 |
| Pileje | Academic/Hospital | 4 | 4 | 3 | 2009 |
| University of Copenhagen | Academic/Hospital | 4 | 4 | 1 | 2006 |
| Hebrew University | Academic/Hospital | 3 | 2 | 2 | 2004 |
| Huazhong University of Science and Technology | Academic/Hospital | 3 | 3 | 2 | 2018 |
| Indian Council of Medical Research | Academic/Hospital | 3 | 1 | 2 | 2007 |
| Laval University | Academic/Hospital | 3 | 2 | 2 | 2006 |
| Lviv National Medical University | Academic/Hospital | 3 | 2 | 2 | 2012 |
| Medical University of Graz | Academic/Hospital | 3 | 3 | 1 | 2015 |
| Osel, Inc. | For profit | 3 | 2 | 2 | 2006 |
| Peking University | Academic/Hospital | 3 | 3 | 2 | 2017 |
| University of North Carolina at Chapel Hill | Academic/Hospital | 3 | 3 | 1 | 2005 |
238 organizations
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