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Fatty Liver
Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
Subtype terms (3)
More specific conditions that are subtypes of Fatty Liver in the MeSH hierarchy.
- Fatty Liver, Alcoholic
3 drugs (1 approved, 2 experimental)
- Non-alcoholic Fatty Liver Disease
436 drugs (141 approved, 295 experimental)
- Reye Syndrome
Drugs by status
Phase 4 trials (29)
- orlistat
- vitamin e
- exenatide
- dulaglutide
- empagliflozin
- liraglutide
- naltrexone
- dolutegravir
- tenofovir
- incretin
- atorvastatin
- ribavirin
- sitagliptin
- semaglutide
- emtricitabine
- testosterone
- bupropion
- triptorelin
- pioglitazone
- dapagliflozin
- raltegravir
- silymarin
- phyllanthus
- tenofovir alafenamide
- rilpivirine
- choline c11
- interferon alpha-2b
- resmetirom
- choline
Phase 3 trials (12)
Phase 2 trials (43)
- obeticholic acid
- procaine benzylpenicillin
- bismuth
- cannabidiol
- gemcabene
- bovine colostrum
- Silipide
- itropride
- jnj-64565111
- ketone
- niacin
- nitazoxanide
- tesamorelin
- acetylsalicylic acid
- digoxin
- pentoxifylline
- spironolactone
- cellulose
- nicotinamide
- furosemide
- autologous microbiome
- bifidobacterium infantis
- Vonafexor
- azithromycin
- cilostazol
- fatty acid
- cysteamine
- omeprazole
- esomeprazole
- hypromelloses
- +13 more
Phase 1 trials (31)
- beetroot juice
- ginger
- insulin human
- 13c-pyruvate
- 11c acetate
- vitamin c
- octreotide
- rifaximin
- growth hormone
- glucose
- glucagon
- bifidobacterium breve
- bifidobacterium longum
- lactobacillus plantarum
- vsl #3
- streptococcus salivarius
- morphine
- docosahexaenoic acid
- eicosapentanoic acid
- tirzepatide
- Lactobacillus acidophilus
- lactobacillus casei
- r-limonene
- ontamalimab
- glyceryl palmitate
- azd7503
- jnj-75220795
- lactobacillus delbrueckii
- ly3849891
- aln-cideb
- +1 more
Other trials (35)
- metformin
- bempedoic acid
- bifidobacterium animalis
- brivanib alaninate
- chiglitazar
- cocoa bean
- alpha-lipoic acid
- somatropin
- green propolis
- citrulline
- ursodeoxycholic acid
- nigella sativa
- pectin
- pegvisomant
- pterostilbene
- resveratrol
- almond
- thyme
- fenofibrate
- amino acids
- canagliflozin
- bacillus coagulans
- orange peel
- salvia
- cherry
- fructose
- arginine
- propionibacterium freudenreichii
- acetobacter
- s-adenosyl methionine
- +5 more
Organizations
Organization Involved with Phase 4 Indications (85)
- University of Texas, Galveston
- Amylin
- University of Lorraine
- Hospital Juarez de Mexico
- University of Medicine and Pharmacy Craiova
- Kuhnil Pharmaceutical Co., Ltd.
- United States Army
- National Health Service, United Kingdom
- National Institutes of Health (NIH)
- University of Pavia
- University of Missouri
- University of Texas, San Antonio
- Xinjiang Medical University
- Kanazawa University
- University of Helsinki
- Federal Ministry of Health, Germany
- IlDong Pharmaceutical Co Ltd
- Catholic University of Korea
- Novo Nordisk
- University of Palermo
- Southern Medical University
- Dong-A Pharmaceutical
- Tanta University
- Duke University
- University of Vienna
- Yonsei University
- Medical College of Wisconsin
- Radboud University
- Fudan University
- Second Military Medical University
- +55 more
Organization Involved with Phase 3 Indications (52)
- Seoul National University
- University of Manitoba
- TransPerfect
- DSM
- Tel Aviv University
- TaiwanJ Pharmaceuticals Co., Ltd
- Institute of Liver and Biliary Sciences, India
- Asian Institute of Gastroenterology
- Galmed Pharmaceuticals Ltd
- Newcastle University
- University of Edinburgh
- PPD
- Cirius Therapeutics, Inc.
- Federal University of Rio de Janeiro
- Gilead Sciences
- NHS Lothian
- Northwestern University
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Intercept Pharmaceuticals
- Rio de Janeiro State University
- Medical Research Council
- Genfit
- National Center for Complementary and Integrative Health (NCCIH)
- University of Antwerp
- Diamond Pharma Services
- Catalysis SL
- ClinIntel
- PharmaKing
- Sharp Clinical Services
- Galectin Therapeutics Inc.
- +22 more
Organization Involved with Phase 2 Indications (183)
- Queen Elizaberth Hospital, Sabah
- Kaohsiung Medical University
- Technion University
- University of Chicago
- Arisaph Pharmaceuticals Inc
- St. Ivan Rilski's University Hospital
- University of Turin
- NorthSea Therapeutics B.V.
- ProSciento, Inc.
- Viking Therapeutics, Inc.
- KT&G Corporation
- Khoo Teck Puat Hospital
- NGM Biopharmaceuticals, Inc
- Pinnacle Research Group
- Amarex Clinical Research
- Nanyang Technological University
- Hanyang University
- Tiziana Life Sciences, PLC
- University of Washington
- EA Pharma Co., Ltd.
- Tengku Ampuau Afzan Hospital, Kuantan
- Ben Gurion University
- University of Paris
- Orphan Medical
- National Cancer Institute (NCI)
- Uppsala University
- 89bio Ltd.
- Integrium
- Beilinson Hospital, Petach Tikva
- Estimate, GmbH
- +153 more
Organization Involved with Phase 1 Indications (34)
- Sunshine Lake Pharma Co., Ltd.
- Prism Research
- Alnylam Pharmaceuticals
- Navidea Biopharmaceuticals
- Shaoguan University
- Autonomous University of Madrid
- Sadat City University
- CohBar, Inc.
- Blade Therapeutics
- Ohio State University
- Guangdong Zhongsheng Pharmaceutical Co., Ltd.
- University of Oxford
- Novotech
- University of North Carolina, Greensboro
- Altimmune, Inc.
- Harokopio University
- Bird Rock Bio, Inc.
- Pharmaceutical Research Associates, Inc. (PRA)
- Hepanova Inc.
- University of Cantabria
- Brown University
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- University of Louisville
- Perspectum Diagnostics Ltd
- Rivus Pharmaceuticals, Inc.
- The Cleveland Clinic
- Jilin University
- Arrowhead Pharmaceuticals
- VSL Pharmaceuticals
- National Institute of General Medical Sciences (NIGMS)
- +4 more
Organization Involved with Other Experimental Indications (64)
- University of Colorado, Denver
- Danish Council for Independent Research
- Region Skane
- CIHR Canadian HIV Trials Network
- Wiener Wissenschafts-, Forschungs- und Technologiefonds
- Chinese University of Hong Kong
- University of Lausanne
- Aarhus University
- Instituto Nacional de Cardiologia Ignacio Chavez
- Nutrasource Diagnostics
- Charles University
- Elysium Health
- Washington University in St. Louis
- China Medical University
- Government of Denmark
- Biovil Research Group, LLC
- Magna Graecia University
- Cedars-Sinai Medical Center
- University of Southern California
- Eurasia Invest Ltd., Kazakhstan
- Sir Salimullah Medical College
- Bogomolets National Medical University
- Forest Laboratories
- Federal University of Bahia
- University of Arkansas
- Xiamen University
- R&G Pharma Studies Co.,Ltd.
- McMaster University
- Steno Diabetes Center Copenhagen
- Laval University
- +34 more