fevipiprant

Small moleculeexperimental

Fevipiprant (INN; code name QAW039) is a drug of the piprant class that was being developed by Novartis. It is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2 or CRTh2). — Wikipedia

Clinical trial activity

20 trials · 2 clinical orgs · 0 marketing orgs

Phase 1
2
Phase 2
17
Phase 3
6
Phase 4
1

Earliest trial started Nov 1, 2010 (NCT01253603)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2015

    Earliest Phase 3 Sponsor(trial)

  3. Jan 1, 2017

    Earliest Phase 1 Sponsor(trial)

Indications

Approved for

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F
Mol. weight
426.42 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • 1-(4-methanesulfonylbenzyl)-2-methyl-1h-pyrrolo(2,3-b)pyridin-3-yl)acetic acid
  • fevipiprant
  • fevipiprant
  • fevipiprant
  • fevipiprant
  • fevipiprant
  • nvp-qaw039
  • nvp-qaw039
  • nvp-qaw039
  • qaw039
  • qaw039
  • qaw039

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03989635Phase 2Aug 16, 2019Novartis
NCT03810183Phase 2May 24, 2019Novartis
NCT03956862Phase 2Apr 30, 2019Gossamer Bio Inc.
NCT03681093Phase 3Jan 21, 2019Novartis
NCT03629249Phase 4Dec 7, 2018Novartis
NCT03650400Phase 2Nov 8, 2018Novartis
NCT03683576Phase 2Sep 26, 2018Gossamer Bio Inc.
NCT03215758Phase 3Nov 1, 2017Novartis
NCT03226392Phase 3Oct 31, 2017Novartis
NCT03087942Phase 1Jun 7, 2017Novartis
NCT03048448Phase 1Jun 5, 2017Novartis
NCT03052517Phase 3Mar 21, 2017Novartis
NCT02555683Phase 3Dec 11, 2015Novartis
NCT02563067Phase 3Dec 3, 2015Novartis
NCT01785602Phase 2Jun 1, 2013Novartis
NCT01836471Phase 2May 1, 2013Novartis
NCT01804400Phase 2Oct 1, 2012Novartis
NCT01545726Phase 2Feb 1, 2012Novartis
NCT01437735Phase 2Aug 1, 2011Novartis
NCT01253603Phase 2Nov 1, 2010Novartis
Showing 20 of 20 trials
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Organizations

Research & Development (2)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
NovartisFor profit181842010
Gossamer Bio Inc.For profit2212018
2 organizations
Page 1 / 1