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Hypersensitivity
Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
Subtype terms (8)
More specific conditions that are subtypes of Hypersensitivity in the MeSH hierarchy.
- Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome
13 drugs (9 approved, 4 experimental)
- Environmental Illness
1 drug experimental
- Hypersensitivity, Delayed
5 drugs (3 approved, 2 experimental)
- Hypersensitivity, Immediate
48 drugs (30 approved, 18 experimental)
- Immune Complex Diseases
1 drug approved
- Kounis Syndrome
- Latex Hypersensitivity
- Wissler's Syndrome
Drugs by status
Approved for this indication (40)
- phenylephrine
- diphenhydramine
- danggui-sayuk-ga-osuyu-saenggang-tang
- prednisone
- dexchlorpheniramine maleate
- fexofenadine
- glycerin
- methylscopolamine bromide
- immunovac
- spaglumic acid
- bilastine
- birch allergen
- tranilast
- cortisone acetate
- coumarin
- zafirlukast
- zileuton
- phenol
- pheniramine
- rye pollens
- histamine antibodies
- phenyltoxamine
- betula
- phenindamine
- novedrine
- methapyrilene
- mepyramine
- alimemazine
- methdilazine
- dextromethorphan
- +10 more
Phase 4 trials (47)
- rupatadine
- azelastine
- vitamin d3
- fluticasone
- vitamin e
- oxytocin
- carbetocin
- cetirizine
- dimeticone
- duloxetine
- nifedipine
- dupilumab
- epinastine
- enalapril
- ginkgo diterpene lactone meglumine
- ginseng
- timothy grass pollen allergen extract
- omalizumab
- ivermectin
- sweet vernal, orchard, perennial rye, timothy, and kentucky blue grass mixed pollens allergen extract
- epinephrine
- house dust mite allergen
- short ragweed pollen allergen
- bupivacaine
- levocetirizine
- bifidobacterium infantis
- bifidobacterium breve
- bifidobacterium longum
- lactobacillus plantarum
- superoxide dismutase
- +17 more
Phase 3 trials (32)
- sodium fluoride (18F)
- urea
- bacille calmette-guerin
- mometasone
- betamethasone
- grazax
- icosapent ethyl
- succinylcholine
- pf-04965842
- formoterol
- sipjeondaebo-tang
- trifolium pratense
- wasp venom
- tree allergen
- clemastine
- peanut allergen
- silver fluoride
- ojeok-san
- albuterol
- budesonide
- dobesilic acid
- butenafine
- olopatadine
- dexamethasone
- lactobacillus casei
- olive
- lactobacillus salivarius
- sodium lauryl sulfate
- bosinji
- streptococcus oralis
- +2 more
Phase 2 trials (27)
- maltodextrin
- azd-2066
- benralizumab
- cyt005-allqbg10
- deferoxamine
- egg
- escitalopram
- peanut
- regn1908
- rifaximin
- rp 01
- il-4r
- toleromune hdm
- paricalcitol
- sodium phosphosilicate
- cat epidermis allergen
- cyt003-qbg10
- depigold olea europea
- depigold judaica
- monofluorophosphate
- onabotulinumtoxinA
- fluorocalcium phosphosilicate
- potassium nitrate
- tezepelumab
- stmc-103h
- mrna-1273
- bnt162b2
Phase 1 trials (17)
Other trials (50)
- tin difluoride
- ciclesonide
- parietaria judaica pollen extract
- bifidobacterium animalis
- oxalate
- loratadine
- coconut oil
- atenolol
- sanfujiu
- histamine
- adenosine
- soybean oil
- recombinant bet v 1
- amoxicillin
- nebivolol
- serum
- vitamin c
- human milk
- cow milk
- propranolol
- rocuronium
- substance p
- articaine
- betaxolol
- pentoxifylline
- autologous microbiome
- carvedilol
- german cockroach allergen extract
- plant stanol
- broccoli sprout
- +20 more
Organizations
Organization Involved with Phase 4 Indications (91)
- Galderma
- Bristol-Myers Squibb
- AstraZeneca
- Genentech
- Pfizer
- Novartis
- Allergopharma GmbH & Co. KG
- GlaxoSmithKline
- Hamilton Health Sciences Corporation
- Jiangsu Kanion Pharmaceutical Co., Ltd
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Public Health England
- Hospital General de México Dr. Eduardo Liceaga
- American Heart Association
- Aston University
- Cairo University
- University of London
- Harvard University
- Gachon University
- Hacettepe University
- Indian Council of Medical Research
- Katholieke Universiteit Leuven
- Kyung Hee University
- Liaocheng People's Hospital
- McMaster University
- Northwestern University
- Postgraduate Institute of Medical Education and Research
- Riyadh Colleges of Dentistry and Pharmacy
- Shandong Provincial Hospital
- Shandong Provincial Institute of Dermatology and Venereology
- +61 more
Organization Involved with Phase 3 Indications (95)
- Regeneron
- Takeda
- Allergy Therapeutics
- Astellas
- Morphotek
- Medivation
- Stallergenes
- Sanofi
- Baxalta
- Bayer
- DBV Technologies
- Grupo Medifarma, S. A. de C. V.
- Hengrui Therapeutics, Inc.
- L'Oreal
- Leti Pharma GmbH
- Myrexis Inc.
- Teva
- United Pharmaceuticals
- Zai Lab Pty. Ltd.
- Colgate Palmolive
- Tesaro
- Global Alliance for TB Drug Development
- Oklahoma Medical Research Foundation
- Medical Research Council
- National Cancer Institute (NCI)
- Fondazione Giovanni Pascale
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institute on Aging (NIA)
- University of Roma La Sapienza
- Huazhong University of Science and Technology
- +65 more
Organization Involved with Phase 2 Indications (149)
- Aragon Pharmaceuticals
- Jazz Pharmaceuticals
- Foundation Medicine
- Eisai
- Celgene
- Amgen
- Bausch Health Companies
- Advanced Accelerator Applications
- Clovis Oncology
- Biomay AG
- MedImmune
- Wyeth
- Aldeyra Therapeutics, Inc.
- AnaptysBio, Inc.
- Anergis
- Antigen Laboratories, Inc.
- Circassia Limited
- Edetec Indústria Alimentícia S.A.
- ERYtech Pharma
- Faes Farma, S.A.
- Gemphire Therapeutics, Inc.
- Greer Laboratories
- Inmunotek S.L.
- Lytix Biopharma AS
- Qurient Co., Ltd.
- Resistentia Pharmaceuticals AB
- Tapimmune Inc.
- Threshold Pharmaceuticals
- Bionomics Limited
- Boehringer Ingelheim
- +119 more
Organization Involved with Phase 1 Indications (43)
- McNeil
- ISTA Pharmaceuticals
- Bausch & Lomb
- Protein Sciences Corp
- Allertein Therapeutics, LLC
- Alcon
- Amicus Therapeutics
- Atopix Therapeutics, Ltd.
- HAL Allergy
- Intron Biotechnology, Inc.
- Mereo BioPharma
- Myovant Sciences GmbH
- PharmAthene
- Tunitas Therapeutics, Inc.
- Ventrus Biosciences, Inc
- Aslan Pharmaceuticals
- Moleac Pte Ltd.
- National Institutes of Health (NIH)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- New York University
- Seoul National University
- Texas Tech University
- Universidade Federal do Para
- University of Florida
- University of Southern California
- University of Virginia
- Mayo Clinic
- University of Montana
- +13 more
Organization Involved with Other Experimental Indications (100)
- Roche
- Novo Nordisk
- Unilever
- Akili Interactive Labs, Inc.
- Allergan
- DSM
- FinnMedi Oy
- InQpharm Group
- National Starch LLC
- NIZO Food Research
- NBTY, Inc.
- Noblewell
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Region Syddanmark
- Tamil Nadu Dr.M.G.R.Medical University
- Chr Hansen
- Bambino Gesù Hospital and Research Institute
- Chang Gung University
- Federal University of Health Science of Porto Alegre
- Federal University of Rio Grande do Sul
- Federal University of Uberlandia
- Georgetown University
- University of Washington
- Guangzhou Medical University
- Hospital Mutua de Terrassa
- Indiana University
- Liverpool John Moores University
- McCabe Vision Center
- Medical University of Bialystok
- Monash University
- +70 more