dobesilic acid

Small moleculeexperimental

Calcium dobesilate is a vasoprotective. It is the calcium salt of dobesilic acid. It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient. — Wikipedia

Clinical trial activity

6 trials · 10 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
1
Phase 3
1
Phase 4
3

Earliest trial started Nov 21, 2012 (NCT03962296)

Timeline

2020s

  1. Jan 1, 2022

    Earliest Phase 2 Sponsor(trial)

Indications

Approved for

Mechanism of action

  • Unspecified targetUnclear

    Unclear

Chemistry & pharmacology

Loading structure…

SMILES

O=S(=O)(O)c1cc(O)ccc1O
Mol. weight
190.18 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • dobesilic acid
  • dobesilic acid

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT06763094N/AJan 5, 2025University of Health Sciences Lahore
NCT05305508Phase 2May 31, 2022OM Pharma, University of Geneva, University of Genoa
NCT06707051Phase 2/Phase 3 (Phase 3)Jan 1, 2022Sahiwal medical college sahiwal
NCT04283162Phase 4Mar 1, 2020Southeast University
NCT03427944Phase 4Jan 31, 2015Xuzhou Medical University
NCT03962296Phase 4Nov 21, 2012Hallym University, Hanlim Pharm. Co., Ltd., Hanyang University
Showing 6 of 6 trials
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Organizations

Research & Development (10)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Hallym UniversityAcademic/Hospital1012012
Hanlim Pharm. Co., Ltd.For profit1012012
Hanyang UniversityAcademic/Hospital1112012
OM PharmaFor profit1012022
Sahiwal medical college sahiwalAcademic/Hospital1112022
Southeast UniversityAcademic/Hospital1112020
University of GenevaAcademic/Hospital1112022
University of GenoaAcademic/Hospital1012022
University of Health Sciences LahoreAcademic/Hospital1112025
Xuzhou Medical UniversityAcademic/Hospital1112015
10 organizations
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