Hypersensitivity, Immediate
Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
Subtype terms (10)
More specific conditions that are subtypes of Hypersensitivity, Immediate in the MeSH hierarchy.
- Anaphylaxis
18 drugs (11 approved, 7 experimental)
- Asthma, Aspirin-Induced
6 drugs (5 approved, 1 experimental)
- Conjunctivitis, Allergic
85 drugs (46 approved, 39 experimental)
- Dermatitis, Atopic
437 drugs (133 approved, 304 experimental)
- Eosinophilic Esophagitis
46 drugs (30 approved, 16 experimental)
- Exercise-Induced Allergies
- Food Hypersensitivity
49 drugs (18 approved, 31 experimental)
- Respiratory Hypersensitivity
5 drugs (4 approved, 1 experimental)
- Urticaria
61 drugs (41 approved, 20 experimental)
- Venom Hypersensitivity
Drugs by status
Approved for this indication (24)
- bee venom
- candida albicans allergen
- orchard grass pollen allergen
- timothy grass pollen allergen extract
- sweet vernal, orchard, perennial rye, timothy, and kentucky blue grass mixed pollens allergen extract
- house dust mite allergen
- short ragweed pollen allergen
- peanut allergen
- cat epidermis allergen
- multiple products: non-standardized allergenics
- redtop grass pollen allergen
- bermuda grass pollen allergen
- kentucky bluegrass pollen allergen
- meadow fescue grass pollen allergen
- sweet vernal grass pollen allergen
- terfenadine
- mixed vespid venom protein
- wasp venom protein
- white faced hornet venom protein
- yellow jacket venom protein
- benzylpenicilloyl polylysine
- yellow hornet venom protein
- Multiple Products Allergen Patch Test Kit
- lolium perenne pollen
Phase 4 trials (1)
Phase 3 trials (2)
Phase 2 trials (5)
Phase 1 trials (1)
Organizations
Organization Involved with Phase 4 Indications (3)
Organization Involved with Phase 3 Indications (4)
Organization Involved with Phase 2 Indications (15)
- Amgen
- AstraZeneca
- National Institute of Allergy and Infectious Diseases (NIAID)
- Duke University
- Hoosier Cancer Research Network
- Johns Hopkins University
- McMaster University
- University of Leicester
- University of Arkansas
- University of Colorado, Denver
- Icahn School of Medicine at Mount Sinai
- University of North Carolina at Chapel Hill
- Sylvana Research Associates
- Allied Research International
- Consortium of Food Allergy Research
Organization Involved with Phase 1 Indications (7)