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potassium nitrate

Small moleculeexperimental

Potassium nitrate is a chemical compound with a sharp, salty, bitter taste and the chemical formula KNO3. It is a potassium salt of nitric acid. This salt consists of potassium cations K+ and nitrate anions NO−3, and is therefore an alkali metal nitrate. It occurs in nature as a mineral, niter. It is a source of nitrogen, and nitrogen was named after niter. Potassium nitrate is one of several nitrogen-containing compounds collectively referred to as saltpetre. — Wikipedia

Clinical trial activity

45 trials · 35 clinical orgs · 0 marketing orgs

Phase 1
4
Phase 2
17
Phase 3
3
Phase 4
0

Earliest trial started Sep 1, 2007 (NCT00752089)

Timeline

2000s

  1. Jan 1, 2007

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2009

    Earliest Phase 1 Sponsor(trial)

2010s

  1. Jan 1, 2015

    Earliest Phase 3 Sponsor(trial)

Indications

Studied for

Mechanism of action

  • Unspecified targetUnclear

    unclear

Chemistry & pharmacology

Loading structure…

SMILES

O=[N+]([O-])[O-].[K+]
Mol. weight
101.1 g/mol
Chirality
Achiral Molecule
Inorganic
Yes
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • e252
  • e252
  • nitric acid potassium salt
  • nitric acid potassium salt
  • paper of potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate
  • potassium nitrate monohydrate
  • saltpeter
  • saltpeter
  • saltpetre

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07215767Phase 3Sep 16, 2025All Sum Research Center Ltd., Healeon Medical Inc, Salus Research
NCT06967818N/AJul 15, 2025University of Pavia
NCT07056855N/AJul 10, 2025Cairo University
NCT06896565N/AJun 1, 2025Cairo University
NCT06871709N/AMay 30, 2025Cairo University, National Research Center, Egypt
NCT06614764N/AOct 31, 2024Universidade Federal do Para
NCT06971783N/AAug 20, 2024Universidade Federal do Para
NCT06216262N/AMar 1, 2024Çanakkale Onsekiz Mart University
NCT06180707Phase 3Jan 5, 2024Universidade Federal do Para
NCT06371092Early Phase 1 (Phase 1)Jan 31, 2023University of Santiago de Compostela
NCT06746558N/AJan 7, 2023University of Genoa, University of Modena and Reggio Emilia, University of Pavia
NCT05562167Phase 2Jan 1, 2023Washington University in St. Louis
NCT05243745N/AFeb 28, 2022Healeon Medical Inc
NCT05138575Phase 2Nov 30, 2021University of Pennsylvania
NCT04913805Phase 2Oct 11, 2021University of Pennsylvania
NCT04964063N/AAug 31, 2021GlaxoSmithKline, IQVIA
NCT04700241N/AJan 21, 2021Maastricht University
NCT04156152N/AApr 10, 2020Universidad del Desarrollo
NCT04179994N/AJan 1, 2020Government of Saudi Arabia
NCT03965039N/AJul 8, 2019Procter and Gamble
Showing 20 of 45 trials
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Organizations

Research & Development (35)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
GlaxoSmithKlineFor profit8832007
University of PennsylvaniaAcademic/Hospital5512015
Cairo UniversityAcademic/Hospital4412017
Universidade Federal do ParaAcademic/Hospital4432017
Healeon Medical IncFor profit2222022
Johnson and JohnsonFor profit2212011
Procter and GambleFor profit2212015
University of PaviaAcademic/Hospital2112023
Washington University in St. LouisAcademic/Hospital2212017
Aarhus UniversityAcademic/Hospital1012018
All Sum Research Center Ltd.For profit1012025
Barts & The London NHS TrustAcademic/Hospital1112018
Çanakkale Onsekiz Mart UniversityAcademic/Hospital1112024
Conselho Nacional de Desenvolvimento Científico e TecnológicoGovernment1012017
Department of Veteran AffairsGovernment1012016
Federal University of AmazonasAcademic/Hospital1112016
Federal University of UberlandiaAcademic/Hospital1112014
Fluminense Federal UniversityAcademic/Hospital1112015
Government Dental College and Research Institute, BangaloreAcademic/Hospital1112017
Government of Saudi ArabiaGovernment1112020
35 organizations
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