fatty acid
Small moleculeexperimental
In biochemistry and nutrition, a polyunsaturated fat is a fat that contains a polyunsaturated fatty acid, which is a subclass of fatty acid characterized by a backbone with two or more carbon–carbon double bonds. Some polyunsaturated fatty acids are essentials. Polyunsaturated fatty acids are precursors to and are derived from polyunsaturated fats, which include drying oils. — Wikipedia
Clinical trial activity
63 trials · 90 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
19
Phase 3
12
Phase 4
7
Earliest trial started Sep 1, 1999 (NCT00010842)
Timeline
Indications
Approved for
Studied for
- Adenomatous Polyposis Coli · Phase 3
- Alcoholism · Phase 3
- alpha-Linolenic Acid · Phase 3
- Anti-Inflammatory Agents · Phase 3
- Atrial Fibrillation · Phase 3
- Attention Deficit and Disruptive Behavior Disorders · Phase 3
- Blepharitis · Phase 4
- Carcinoma, Hepatocellular · Phase 2/Phase 3
- Cardiomyopathy, Dilated · Phase 3
- Cardiovascular Diseases · Phase 3
- Child Development · Phase 2
- Conjunctivitis · Phase 2
- Critical Illness · Phase 4
- Docosahexaenoic Acids · Phase 3
- Drug-Related Side Effects and Adverse Reactions · Phase 1/Phase 2
- Dry Eye Syndromes · Phase 4
- Eicosapentaenoic Acid · Phase 3
- Fatty Acids · Phase 3
- Fatty Liver · Phase 2
- Fibrosis · Phase 2/Phase 3
- Health Behavior · Phase 2
- Healthy Volunteers · Phase 1
- Heart Failure · Phase 3
- Hemolysis · Phase 2
- Hypertriglyceridemia · Phase 4
- Inflammation · Phase 2
- Kidney Failure, Chronic · Phase 2
- Liver Cirrhosis · Phase 2/Phase 3
- Liver Neoplasms · Phase 4
- Maternal Exposure · Phase 2
- Multiple Sclerosis · Phase 1/Phase 2
- Obesity · Phase 3
- Obesity, Morbid · Phase 2
- Pancreatic Neoplasms · Phase 4
- Parenteral Nutrition · Phase 3
- Pressure Ulcer · Phase 4
- Preventive Health Services · Phase 3
- Preventive Medicine · Phase 3
- Procedural Sedation · Phase 3
- Prostatic Neoplasms · Phase 1/Phase 2
- Rhinitis, Allergic · Early Phase 1
- SARS-CoV-2 · Phase 3
- Schizophrenia · Phase 4
- Stomach Neoplasms · Phase 4
Mechanism of action
- Unspecified targetSupplementation
supplementation
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaPolyunsaturated fat ↗
- WikipediaShort-chain fatty acid ↗
- WikipediaPolyunsaturated fatty acid ↗
- WikipediaMedium-chain triglyceride ↗
- WikipediaFatty acid ↗
- WikipediaFat ↗
- WikipediaUnsaturated fat ↗
- WikipediaEssential fatty acid ↗
Also known as
- dha-enriched omega-3 polyunsaturated fatty acid
- epa-enriched omega-3 polyunsaturated fatty acid
- essential fatty acids
- fatty acid
- hyper-oxigenated fatty acid
- long-chain fatty acids
- medium chain fatty acid
- medium-chain fatty acid
- medium-chain fatty acids
- medium-chain saturated fatty acids
- middle-chain fatty acids
- n-3 pufa
- n-3 pufa
- polyunsaturated fatty acid
- polyunsaturated fatty acids
- reesterified long-chain n-3 polyunsaturated fatty acids
- unsaturated fatty acids
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07024238 | N/A | Apr 4, 2025 | Abecma, University Hospital, Martin |
| NCT06595680 | Phase 2 | Jan 1, 2025 | University of Lyon |
| NCT06699030 | N/A | Dec 1, 2024 | Hepatopancreatobiliary Surgery Institute of Gansu Province |
| NCT06686888 | N/A | Sep 25, 2024 | Katholieke Universiteit Leuven |
| NCT07016763 | Early Phase 1 (Phase 1) | Sep 1, 2024 | Isola Tiberina - Gemelli Isola Hospital, Rome, Italy |
| NCT06222294 | Phase 3 | Mar 12, 2024 | Hengrui Therapeutics, Inc. |
| NCT06951581 | N/A | Jan 15, 2024 | Abecma, University Hospital, Martin |
| NCT06150261 | N/A | Dec 31, 2023 | University of Stavanger |
| NCT06082726 | N/A | Oct 9, 2023 | Katholieke Universiteit Leuven |
| NCT05650294 | N/A | Jan 31, 2023 | Aker Biomarine Antarctic AS, BioTeSys GmbH |
| NCT04700527 | Phase 1/Phase 2 (Phase 2) | Apr 30, 2022 | University of North Carolina at Chapel Hill |
| NCT05267301 | N/A | Mar 1, 2022 | Arizona State University, Qualitas Health |
| NCT05144646 | N/A | Jan 4, 2022 | University of Malaga |
| NCT05152615 | N/A | Nov 17, 2021 | New York University |
| NCT04977778 | N/A | Sep 1, 2021 | University of L'Aquila |
| NCT04958382 | N/A | Aug 10, 2021 | Sichuan University |
| NCT05198167 | N/A | Jun 12, 2021 | Autonomous University of Madrid, Universidad Autonoma de Madrid |
| NCT04743050 | Phase 3 | Dec 9, 2020 | Wroclaw Medical University |
| NCT04335032 | Phase 3 | Apr 13, 2020 | SLA Pharma |
| NCT03851120 | Phase 2 | Jul 1, 2019 | Grand Challenges Canada, Indonesian Medical Education Research Institute, University of Indonesia |
Showing 20 of 63 trials
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Organizations
Research & Development (90)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Osaka University | Academic/Hospital | 3 | 0 | 2 | 2007 |
| Abecma | For profit | 2 | 0 | 1 | 2024 |
| B. Braun | For profit | 2 | 2 | 2 | 2006 |
| Department of Veteran Affairs | Government | 2 | 1 | 2 | 1999 |
| Katholieke Universiteit Leuven | Academic/Hospital | 2 | 2 | 1 | 2023 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Government | 2 | 1 | 2 | 2005 |
| Northumbria University | Academic/Hospital | 2 | 2 | 1 | 2007 |
| SLA Pharma | For profit | 2 | 2 | 1 | 2018 |
| Universidad Autonoma de Madrid | Academic/Hospital | 2 | 0 | 2 | 2006 |
| University Hospital, Martin | Academic/Hospital | 2 | 2 | 1 | 2024 |
| University of Bologna | Academic/Hospital | 2 | 1 | 2 | 2014 |
| University of Brescia | Academic/Hospital | 2 | 2 | 1 | 2006 |
| University of Oslo | Academic/Hospital | 2 | 2 | 2 | 2007 |
| University of Rochester | Academic/Hospital | 2 | 0 | 2 | 2006 |
| Aarhus University | Academic/Hospital | 1 | 1 | 1 | 2011 |
| Aker Biomarine Antarctic AS | For profit | 1 | 1 | 1 | 2023 |
| Akorn, Inc. | For profit | 1 | 0 | 1 | 2004 |
| Andaluz Health Service | Academic/Hospital | 1 | 1 | 1 | 2012 |
| Arizona State University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Arla Foods | For profit | 1 | 0 | 1 | 2011 |
90 organizations
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