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Dermatitis, Atopic
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
Drugs by status
Approved for this indication (20)
Phase 4 trials (37)
- salicylic acid
- cow milk
- retapamulin
- dicloxacillin
- house dust mite allergen
- chickpea
- coal tar
- upadacitinib
- omalizumab
- epiceram
- alefacept
- dihomo-gamma-linolenic acid
- mupirocin
- alitretinoin
- tacrolimus
- lactic acid
- lactobacillus casei
- mycophenolate
- mometasone
- ruxolitinib
- niacinamide
- methotrexate
- tofacitinib
- hypochlorous acid
- levocetirizine
- aqualan
- montelukast
- aluminum hydroxide
- vitamin d3
- bifidobacterium animalis
- +7 more
Phase 3 trials (60)
- Ivarmacitinib
- lactobacillus sakei
- melatonin
- desloratadine
- cetirizine
- Difamilast
- cellulose
- gr1802
- stapokibatrt
- autologous microbiome
- amino acids
- cm310
- paraffin oil
- cbp-201
- jaktinib
- vc005
- prednisolone
- ketotifen
- maltodextrin
- ecologic
- galactooligosaccharide
- Bacterial Lysates
- palmitoylethanolamide
- epinastine
- ky1005
- tradipitant
- shr-1819
- pf-04965842
- qy201
- tqh2722
- +30 more
Phase 2 trials (195)
- ustekinumab
- mepolizumab
- sar443765
- indigo
- Taurodeoxycholate
- lucinactant
- palmityl alcohol
- imidazole-4-carboxylic acid
- cm326
- m516102
- bimekizumab
- ly3375880
- ro7790121
- ab-101
- khk4083
- leo 29102
- pf-03893787
- Rilzabrutinib
- panthenol
- cdx-0159
- ligelizumab
- vtp-38543
- dmt210
- indirubin sulfate
- allogeneic stem cells
- aslan004
- Janthinobacterium lividum
- danegaptide
- xkh001
- pf-07264660
- +165 more
Phase 1 trials (73)
- Veillonella parvula
- nvn1000
- cpi-818
- ibi356
- loratadine
- pf-07242813
- ipg7236
- pf-07832837
- fluconazole
- autologous mesenchymal stem cells
- edp1066
- oryza sativa
- keyhole limpet hemocyanin
- nortriptyline
- ly3471851
- ly3844583
- si-544
- leo 39652
- bgb-45035
- sm17
- mk8226
- human fecal microbiota
- bbi-5000
- cee321
- mk-6194
- tll-018
- gb-7624
- midazolam
- lactobacillus gasseri
- mva
- +43 more
Other trials (52)
- vitreoscilla filiformis
- saccharide isomerate
- hydrolysed whey protein
- menthoxypropanediol
- prednicarbate
- etanercept
- xiao-xian-gui-fu-tang
- fish oil
- bacille calmette-guerin
- ceramide
- octocrylene
- pioglitazone
- lactobacillus delbrueckii
- cd4cd8aa
- canola oil
- photocil
- p-aminobenzoic acid
- lactobacillus fermentum
- fusidic acid
- saccharomyces boulardii
- mare milk
- lactobacillus reuteri
- icosapent ethyl
- rouvax
- dimetindene
- oregano extract
- oligo fucoidan
- mineral oil
- rituximab
- infliximab
- +22 more
Organizations
Organization Involved with Phase 4 Indications (67)
- Icahn School of Medicine at Mount Sinai
- University of Miami
- Derm Research, PLLC
- Monash University
- University of Texas, Galveston
- Astellas
- Dell Children's Medical Center
- Stanford University
- Ceragenix Pharmaceuticals
- Radboud University
- Technical University of Dresden
- University of Michigan
- University of Sao Paulo
- University of Zurich
- University of Pennsylvania
- Libbs Farmacêutica LTDA
- Wake Research Associates
- Max Zeller Soehne AG
- Sanofi
- Procter and Gamble
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Wake Forest University
- Perrigo
- Adult & Pediatric Dermatology
- University of California, Davis
- Johnson and Johnson
- Innovaderm
- Rush University
- Government of Finland
- Mead Johnson
- +37 more
Organization Involved with Phase 3 Indications (58)
- University of Indonesia
- Boehringer Ingelheim
- Chang Gung University
- Agentschap NL
- Vyne Therapeutics Inc.
- NeoStrata Company, Inc.
- Amorepacific Corporation
- Mylan
- Luigi Sacco University Hospital
- St. Antonius Hospital, Nieuwegein
- Chungbuk National University
- Eli Lilly
- Taro Pharmaceuticals
- Bausch Health Companies
- Galderma
- Yeungnam University
- University of Milan
- Vifor Inc.
- Gachon University
- Merz
- Uppsala University
- ALK-Abello, S.A.
- University of Padova
- Seoul National University
- Kang Stem Biotech Co., Ltd.
- Pierre Fabre
- National Hepatology & Tropical Medicine Research Institute
- Par Pharmaceuticals
- Ludwig Maximilians University
- Vanda Pharmaceuticals
- +28 more
Organization Involved with Phase 2 Indications (160)
- University of Barcelona
- Cutanea Life Sciences, Inc.
- Janssen Pharmaceutica NV
- Universidad Autonoma de Madrid
- DermBiont, Inc.
- Vitae Pharmaceuticals
- Laniado Medical Center
- Valletta Health B.V.
- Golden Biotechnology Corp.
- Sheffield Hallam University
- Union Therapeutics
- Stephens & Associates, Inc
- Lytix Biopharma AS
- Central South University
- AnaMar AB
- Reistone Biopharma Company Limited
- Kymab Limited
- University of Colorado, Denver
- AstraZeneca
- SCM Lifescience Co., LTD.
- Tufts University
- Aquinox Pharamceuticals Inc
- Rutgers University
- Kaken Pharmaceutical Co.,Ltd.
- Inha University
- University of Bern
- Almirall
- Amgen
- Amytrx Therapeutics, Inc.
- Hemay Pharmaceutical PTY. LTD.
- +130 more
Organization Involved with Phase 1 Indications (29)
- Pharmaceutical Research Associates, Inc. (PRA)
- Parexel
- Atopic Dermatitis and Vaccinia Network
- Aslan Pharmaceuticals
- Evelo Biosciences
- Dr. August Wolff GmbH & Co. KG Arzneimittel
- MorphoSys
- Bristol-Myers Squibb
- Makati Medical Center
- KoBioLabs
- University of Surrey
- Xencor
- Weizmann Institute of Science
- Akeso Pharmaceuticals, Inc.
- Novotech
- RCSI & UCD Malaysia Campus
- LCG Bioscience
- Zalicus
- Loh Guan Lye Specialist Centre
- Proinnovera GmbH
- RAPT Therepeutics, Inc.
- Stiefel Laboratories
- Nektar Therapeutics
- Novan, Inc.
- Nucleus Network Ltd
- J. W. Goethe University
- University of Nebraska
- Medicines Evaluation Unit Ltd
- Brickell Biotech, Inc.
Organization Involved with Other Experimental Indications (54)
- Korott, S.L.
- University of California, Los Angeles
- Utrecht University
- Karolinska Institute
- Friedrich Schiller University
- Umea University
- GenMont Biotech Incorporation
- Nestle
- Aarhus University
- Clinica Pediatrica Ospedale dei Bambini Vittore Buzzi
- Medical College of Wisconsin
- Numico Research
- The Netherlands Asthma Foundation
- Chinese Academy of Medical Sciences
- IlDong Pharmaceutical Co Ltd
- South African Medical Association
- Beiersdorf
- Norwegian University of Science and Technology
- University of Bonn
- Fraunhofer
- Soonchunhyang University
- BioGaia AB
- Association pour la Recherche Clinique et Immunologique
- Institut National de la Santé Et de la Recherche Médicale, France
- Thrasher Research Fund
- University of Nantes
- Pontificia Universidad Catolica de Chile
- Foundation for Research Support of the State of São Paulo
- Heinz
- Srinakharinwirot University
- +24 more