← All indications
Depressive Disorder
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
Subtype terms (7)
More specific conditions that are subtypes of Depressive Disorder in the MeSH hierarchy.
- Depression, Postpartum
49 drugs (40 approved, 9 experimental)
- Depressive Disorder, Treatment-Resistant
79 drugs (53 approved, 26 experimental)
- Dysthymic Disorder
20 drugs approved
- Major Depressive Disorder
356 drugs (187 approved, 169 experimental)
- Premenstrual Dysphoric Disorder
16 drugs (10 approved, 6 experimental)
- Seasonal Affective Disorder
4 drugs approved
- Vascular Depression
4 drugs approved
Drugs by status
Approved for this indication (17)
Phase 4 trials (17)
Phase 3 trials (16)
Phase 2 trials (34)
- nitrous oxide
- oxytocin
- mecamylamine
- epoetin
- dehydroepiandrosterone
- perampanel
- ezogabine
- ganaxolone
- naltrexone
- gsk163090
- cyanocobalamin
- i-123-adam
- jnj-42165279
- niacin
- gsk372475
- orvepitant
- atorvastatin
- nicotine
- scopolamine
- acetylsalicylic acid
- tianeptine
- ursolic acid
- volinanserin
- xanamem
- dapagliflozin
- nelivaptan
- org-34517
- psilocybin
- dextromethorphan
- sulforaphane
- +4 more
Phase 1 trials (12)
Other trials (35)
- vitamin d3
- agomelatine
- paroxetine
- Casopitant
- duloxetine
- fluvoxamine
- escitalopram
- sertraline
- imipramine
- esketamine
- lorazepam
- fluoxetine
- mianserin
- moclobemide
- prucalopride succinate
- reboxetine
- zuranolone
- clomipramine
- desvenlafaxine
- testosterone
- vilazodone
- vortioxetine
- lycium barbarum
- magnesium glycinate
- varenicline
- jwxyjn
- mirtazapine
- trimipramine
- nortriptyline
- milnacipran
- +5 more
Organizations
Organization Involved with Phase 4 Indications (282)
- Cornell University
- University of British Columbia
- University of Strasbourg
- National Center for Complementary and Integrative Health (NCCIH)
- Karolinska Institute
- Wyeth
- Ybrain Inc.
- University of Pittsburgh
- Bausch Health Companies
- University of Bergen
- Lundbeck
- Brain & Behavior Research Foundation
- University of Illinois at Chicago
- Monash University
- Janssen Pharmaceutica NV
- Jerusalem Mental Health Center
- Stanford University
- Danish Heart Foundation
- Collaborative Care Initiative, LLC
- BRC Operations Pty. Ltd.
- Region Syddanmark
- University of Nebraska
- University of Sao Paulo
- Society of Family Planning
- Wuhan University
- Valley Medical Research
- University of Arizona
- Kunming Medical University
- Canadian Research Initiative in Substance Misuse
- Huazhong University of Science and Technology
- +252 more
Organization Involved with Phase 3 Indications (122)
- BC Women's Hospital & Health Centre
- Bracket Global
- Pascoe Pharmazeutische Praeparate GmbH
- Sumitomo Dainippon
- Psychiatric University Hospital, Zurich
- Gedeon Richter Ltd.
- Bayer
- University of Nimes
- Hebei University
- University of Lille
- Dow University of Health Sciences
- Federal University of Health Science of Porto Alegre
- University of Vermont
- Southwest Medical University
- NeuroRx, Inc.
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
- Rawalpindi Medical College, Pakistan
- National Center of Neurology and Psychiatry, Japan
- National Institute of Neurological Disorders and Stroke (NINDS)
- Lallemand SAS
- Office of Dietary Supplements (ODS)
- University of Turin
- Federal University of Bahia
- Florida Clinical Research Center, LLC
- University of Texas at Houston
- University of Freiburg
- Region Skane
- University of Connecticut
- University of Oklahoma
- PharmaNeuroBoost N.V.
- +92 more
Organization Involved with Phase 2 Indications (162)
- Seton Healthcare Family
- Synergy Pharmaceuticals
- Boston Clinical Trials
- MIND Foundation gGmbH
- Dr. D McIntosh & Dr. K Kjernisted Clinical Research Inc.
- Donaghue Foundation
- Alexander Mosely Charitable Trust
- Brigham and Women's Hospital
- Melbourne Health
- Boston University
- Chiba University
- CNS Healthcare
- BioLite, Inc.
- Comprehensive Psychiatric Care, Norwich CT
- Dart NeuroScience, LLC
- Hospital Juarez de Mexico
- Cerecor Inc
- Reckitt Benckiser Pharmaceutical
- Concordia University
- Seelos Therapeutics
- Oregon Center for Clinical Investigations, Inc
- Medical University of Bialystok
- Affectis Pharmaceuticals AG
- Jinlin University
- University of Louisville
- The Segal Institute of Clinical Research
- Government of Australia
- Carman Research
- Oslo Metropolitan University
- Universidade Federal do Rio Grande do Norte
- +132 more
Organization Involved with Phase 1 Indications (40)
- Algorithme Pharma Inc
- Repurposed Therapeutics, Inc.
- Central Visitation, Region Hovedstaden
- Anhui Medical University
- PPD
- Harbin Medical University
- National Network of Depression Centers
- Wuhan Psychiatric Hospital
- St Patrick's Hospital
- St. Louis Clinical Trials, LC
- Pharmaceutical Research Associates, Inc. (PRA)
- Chongqing Medical University
- Affective Neuroscience Laboratory
- Sunshine Lake Pharma Co., Ltd.
- Suven Life Sciences Limited
- Taipei Veteran General hospital
- Medical University of Vienna
- Navitor Pharmaceuticals, Inc.
- Assiut University
- Chicago Research Center, Inc.
- Gate Neurosciences, Inc
- Heffter Research Institute
- Shenox Pharmaceuticals, LLC
- Hunan DongtingPharm.Co.Ltd
- Comprehensive Clinical Development, Inc.
- Tianjin Medical University
- Beijing Winsunny Pharmceutical Co.,Ltd.
- Rhode Island Hospital
- Kufa University
- University of Stavanger
- +10 more
Organization Involved with Other Experimental Indications (83)
- The Depressive and Bipolar Disorder Alternative Treatment Foundation
- Aga Khan University
- Danish University
- University of Salerno
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Makerere University
- Aalborg University
- Jagiellonian University
- Collective Healthcare Solutions, LLC
- Dalian Seventh People's Hospital
- Showa University
- Chimei Medical Center
- Abarbanel Mental Health Center
- Leon J. Epstein Endowment
- Tanta University
- Tsinghua University
- The Korean Society of Ginseng
- University Hospital, Tours
- Center Abarbanel Mental Health
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
- University of Wisconsin
- NeuroCure Clinical Research Center
- Government of China
- Universitaetsklinikum Schleswig-Holstein
- Kenya Medical Research Institute
- Yeshiva University
- University of Turku
- Fudan University
- JayMac Pharmaceuticals, LLC
- Rowan University
- +53 more