fozivudine tidoxil
Small moleculeexperimental
Clinical trial activity
2 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Nov 2, 1999 (NCT00002385)
Timeline
2010s
- Jan 1, 2012
Earliest Phase 2 Sponsor(trial)
Indications
Studied for
Mechanism of action
- Reverse transcriptaseINHIBITOR
Reverse transcriptase inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
CCCCCCCCCCCCSCC(COP(=O)(O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1N=[N+]=[N-])OCCCCCCCCCC- Mol. weight
- 745.96 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3989603 ↗
Also known as
- (2,rs)-2-(decyloxy)-3-(dodecylthio)propyl hydrogen 3'-azido-3'-deoxy-5'-thymidylate
- bm 21.1290
- bm21.1290
- fozivudine
- fozivudine
- fozivudine tidoxil
- fozivudine tidoxil
- fozivudine tidoxil
- fozivudine tidoxil
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT01714414 | Phase 2 | Dec 1, 2012 | Bernhard Nocht Institute for Tropical Medicine, Chiracon GmbH, European and Developing Countries Clinical Trials Partnership (EDCTP), German Federal Ministry of Education and Research, Government of France, Kumasi Centre for Collaborative Research, Ludwig Maximilians University, National Institute for Medical Research, Tanzania, STADA Arzneimittel AG, Treichville Academic hospital center |
| NCT00002385 | N/A | Nov 2, 1999 | Anderson Clinical Research, Boehringer-Mannheim |
Showing 2 of 2 trials
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Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Anderson Clinical Research | For profit | 1 | 1 | 1 | 1999 |
| Bernhard Nocht Institute for Tropical Medicine | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Boehringer-Mannheim | For profit | 1 | 0 | 1 | 1999 |
| Chiracon GmbH | For profit | 1 | 0 | 1 | 2012 |
| European and Developing Countries Clinical Trials Partnership (EDCTP) | Academic/Hospital | 1 | 0 | 1 | 2012 |
| German Federal Ministry of Education and Research | Government | 1 | 0 | 1 | 2012 |
| Government of France | Government | 1 | 0 | 1 | 2012 |
| Kumasi Centre for Collaborative Research | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Ludwig Maximilians University | Academic/Hospital | 1 | 1 | 1 | 2012 |
| National Institute for Medical Research, Tanzania | Government | 1 | 0 | 1 | 2012 |
| STADA Arzneimittel AG | For profit | 1 | 0 | 1 | 2012 |
| Treichville Academic hospital center | Academic/Hospital | 1 | 0 | 1 | 2012 |
12 organizations
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