← All indications
Seizures
Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
Subtype terms (4)
More specific conditions that are subtypes of Seizures in the MeSH hierarchy.
- Alcohol Withdrawal Seizures
2 drugs approved
- Psychogenic Nonepileptic Seizures
1 drug experimental
- Seizures, Febrile
9 drugs (5 approved, 4 experimental)
- Status Epilepticus
23 drugs (20 approved, 3 experimental)
Drugs by status
Approved for this indication (40)
- phenobarbital
- acetazolamide
- brivaracetam
- lamotrigine
- clobazam
- clonazepam
- clorazepate
- valproic acid
- perampanel
- cannabidiol
- eslicarbazepine acetate
- ezogabine
- felbamate
- fosphenytoin
- gabapentin
- ganaxolone
- carbamazepine
- levetiracetam
- topiramate
- magnesium sulfate
- primidone
- s-licarbazepine
- stiripentol
- rufinamide
- diazepam
- zonisamide
- lacosamide
- tiagabine
- pregabalin
- sulfate
- +10 more
Phase 4 trials (12)
Phase 3 trials (10)
Phase 2 trials (15)
Phase 1 trials (4)
Organizations
Organization Involved with Phase 4 Indications (67)
- Eisai
- Astellas
- Medivation
- GlaxoSmithKline
- Hamad Medical Corporation
- Yung Shin Pharm. Ind. Co., Ltd.
- National Cancer Institute (NCI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- Hospital Universitari de Bellvitge
- University of Pennsylvania
- University of Pittsburgh
- Brown University
- Cairo University
- Duke University
- Emory University
- Guangxi Medical University
- Guangzhou Medical University
- Hoosier Cancer Research Network
- Hospital Mutua de Terrassa
- Indiana University
- Kaiser Permanente
- Loyola University
- Mazandaran University of Medical Sciences
- McMaster University
- Medical Center Haaglanden
- Medical College of Wisconsin
- Rhode Island Hospital
- Stanford University
- Tanta University
- Universidad Autonoma de Madrid
- +37 more
Organization Involved with Phase 3 Indications (51)
- Ache Laboratorios Farmaceuticos S.A.
- Glaxo Wellcome
- Hikma
- Marinus Pharmaceuticals
- Neurelis, Inc.
- Parexel
- Arvelle
- Valexfarm
- West-Ward Pharmaceutical
- Xenon Pharmaceuticals Inc.
- Upsher-Smith Laboratories
- Zogenix, Inc.
- National Institutes of Health (NIH)
- National Institute of Allergy and Infectious Diseases (NIAID)
- Harvard University
- Institut National de la Santé Et de la Recherche Médicale, France
- Scienze Neurologiche Ospedaliere
- Cayetano Heredia University
- University of South Alabama
- Yonsei University
- University of California, San Francisco
- University of Utah
- GW Research
- Jean Monnet University
- University of Strasbourg
- University of Malawi
- Harborview Injury Prevention and Research Center
- University of Lille
- Pharmaceutical Research Associates, Inc. (PRA)
- University of Lyon
- +21 more
Organization Involved with Phase 2 Indications (38)
- Vitaflo
- Neuronex, Inc.
- Acorda Therapeutics
- Jazz Pharmaceuticals
- AstraZeneca
- Biogen
- Baxalta
- Biscayne Neurotherapeutics, Inc.
- Cavion LLC
- Cerebral Therapeutics LLC
- National Center for Complementary and Integrative Health (NCCIH)
- University of London
- Johns Hopkins University
- Makerere University
- Neuroscience Trials Australia
- University of Iowa
- University of Lausanne
- University of Leeds
- University of South Carolina
- Utrecht University
- University of California, Los Angeles
- University of California, San Diego
- Uppsala University
- University of Auckland
- University of Minnesota
- François Rabelais University
- University of Toulouse
- Karolinska Institute
- Louisiana State University
- University of Oxford
- +8 more
Organization Involved with Phase 1 Indications (13)
- Sandoz
- Whanin Pharmaceutical Company
- Roxane Laboratories
- United States Army
- Huazhong University of Science and Technology
- Seoul National University
- Worldwide Clinical Trials
- MDS Pharma
- Pharma Medica
- University of Alabama, Birmingham
- Bioanalytical Systems, Inc.
- Citizens United for Research in Epilepsy
- Charles H. Hood Foundation
Organization Involved with Other Experimental Indications (19)
- Dutch Epilepsy Clinics Foundation
- Loma Linda University
- New York University
- Northern State Medical University
- Northwestern University
- Ohio State University
- Queen Sirikit National Institute of Child Health
- University of Florida
- University of Toronto
- Virginia Commonwealth University
- Capital Medical University
- Virginia Polytechnic Institute and State University
- International Center for Diarrheal Disease Research
- Novum Pharmaceutical Research Services
- University of Texas at Houston
- Bio-Kinetic Clinical Applications
- Dhaka Medical College
- James S McDonnell Foundation
- Brain Tumor Trials Collaborative