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Dysentery, Bacillary
DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest).
Drugs by status
Approved for this indication (2)
Phase 4 trials (2)
Phase 3 trials (3)
Phase 2 trials (15)
- flexyn2a
- inactivated rabies vaccine
- ceftriaxone
- sc599
- shigella flexneri 2a whole cell vaccine
- sodium butyrate
- invaplex 50 vaccine
- wrss2
- meningococcal (groups A, C, Y, W) tetanus toxoid conjugate vaccine
- haemophilus influenzae type b conjugate vaccine
- acellular pertussis vaccine (including diptheria and tetanus toxoids)
- sodium chloride
- tebipenem
- gsk3536852a
- Sextaphag
Phase 1 trials (13)
- aluminum
- shigella sonnei ospc-rdt conjugate vaccine
- dmlt
- gvgh shigella sonnei 1790gahb vaccine
- s. sonnei 1790gahb
- sf2a-tt15 vaccine
- shigella flexneri 2a invaplex 50
- shigella sonnei o-spc/rbru
- wrss3
- detoxified shigella flexneri 2a artificial invasin complex
- s. flexneri 2a 2457t
- shigella sonnei strain 53g
- strain cvd 1208s-122
Other trials (1)
Organizations
Organization Involved with Phase 4 Indications (3)
Organization Involved with Phase 3 Indications (4)
Organization Involved with Phase 2 Indications (20)
- GlaxoSmithKline
- Institut Pasteur
- LimmaTech Biologics AG
- Parexel
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- National Institute of Allergy and Infectious Diseases (NIAID)
- United States Army
- United States Navy
- University of London
- Kenya Medical Research Institute
- Johns Hopkins University
- Mahidol University
- University of Maryland
- Department of Defense
- Wellcome Trust
- Bill and Melinda Gates Foundation
- Government of Sweden
- Government of Thailand
- PATH
- ClinWin Research
Organization Involved with Phase 1 Indications (3)