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Dry Eye Syndromes
Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.
Subtype terms (3)
More specific conditions that are subtypes of Dry Eye Syndromes in the MeSH hierarchy.
- Keratoconjunctivitis Sicca
29 drugs (17 approved, 12 experimental)
- Sjogren's Syndrome
131 drugs (54 approved, 77 experimental)
- Xerophthalmia
4 drugs (2 approved, 2 experimental)
Drugs by status
Approved for this indication (16)
Phase 4 trials (51)
- fluorometholone
- levofloxacin
- azelastine
- vitamin d3
- corticotropin
- vitamin e
- tobramycin
- bromfenac
- castor oil
- chondroitin
- doxycycline
- prednisone
- latanoprost
- tacrolimus
- travoprost
- glycerin
- insulin human
- hydrocortisone
- icosapent ethyl
- manuka honey
- autologous serum
- ketorolac
- platelet-rich plasma
- N-acetyl-aspartyl-glutamate
- pilocarpine
- hyaluronic acid
- cyclosporine
- trehalose
- cellulose
- menthol
- +21 more
Phase 3 trials (44)
- tavilermide
- ezetimibe
- sodium citrate
- brimonidine
- methylprednisolone
- ebi-005
- agn-195263
- urea
- bardoxolone
- ins365
- hydroxychloroquine
- si-614
- Fonadelpar
- serum
- atorvastatin
- thymosin beta-4
- voclosporin
- xenobella
- brm421
- recoflavone
- top1630
- trimix
- insulin lispro
- pregabalin
- syl-1001
- ticlopidine
- esomeprazole
- onabotulinumtoxinA
- blueberry
- reproxalap
- +14 more
Phase 2 trials (68)
- adx-102
- agn-223575
- secukinumab
- al-38583
- acetylcysteine
- canakinumab
- cevimeline hydrochloride
- chitosan
- cis-urocanic acid
- tofacitinib
- progesterone
- difluprednate
- betamethasone
- dornase alfa
- esba105
- naltrexone
- ganciclovir
- ozagrel
- kl7016
- kls-0611
- p-321
- pg101
- dipyridamole
- immune globulin (human)
- rivoglitazone
- ru-101
- rx-10045
- sirolimus
- acetylsalicylic acid
- mycophenolate
- +38 more
Phase 1 trials (20)
- amnion-derived cellular cytokine
- agn-232411
- autologous plasma
- oxycodone
- epidermal growth factor
- cabergoline
- naproxen
- rimabotulinumtoxinB
- palovarotene
- acetaminophen
- polyacrylamide
- spironolactone
- autologous mesenchymal stem cells
- naloxone
- panthenol
- autologous adipose-derived mesenchymal stem cells
- telisotuzumab vedodin
- aCT1
- ksr-004
- jn002
Other trials (35)
- coconut oil
- denufosol
- fid 114657
- linseed oil
- ginseng
- soybean oil
- omega-6 fatty acids
- platelet poor plasma
- prulifloxacin
- sunflower oil
- terpinen-4-ol
- bilberry
- cordyceps sinensis mycelium culture extract
- polidronium
- walnut
- zanthoxylum schinifolium seed oil
- tetronic 1304
- borage
- chloramphenicol
- polypropylene glycol
- tetracycline
- ex vivo expanded autologous human corneal epithelial cells containing stem cells
- fish oil
- saffron
- amniotic fluid
- t2769
- fulvic acid
- mineral oil
- fid123238
- ngf4-b
- +5 more
Organizations
Organization Involved with Phase 4 Indications (76)
- Bausch & Lomb
- Merck
- Akorn, Inc.
- Novartis
- Allergan
- Bp Consulting, Inc
- Santen Inc.
- GlaxoSmithKline
- Laboratoires Thea
- Laboratorios Sophia S.A de C.V.
- Mallinckrodt
- Ocular Therapeutix, Inc.
- Ocusoft, Inc.
- ORA, Inc.
- Samil Pharmaceutical Co., Ltd.
- Sun Pharmaceuticals
- Taejoon Pharm Co., Ltd.
- Lifelong Vision Foundation
- Edward Holland, MD
- University of Pittsburgh
- Chang Gung University
- Chulalongkorn University
- Cornell University
- Harvard University
- Eye and Vision Technologies and Research Institute
- Hermann Eye Center
- Koffler Vision Group
- Niğde State Hospital
- Ohio State University
- Ophthalmic Consultants of Long Island
- +46 more
Organization Involved with Phase 3 Indications (69)
- Inspire Pharmaceuticals
- Acucela Inc.
- Senju Pharmaceuticals
- Sirion Therapeutics
- ISTA Pharmaceuticals
- Aldeyra Therapeutics, Inc.
- Aurinia Pharmaceuticals Inc.
- BRIM Biotechnology Inc.
- C.T. Development America, Inc.
- Can-Fite BioPharma
- DH Bio Co., Ltd.
- Eyegate Pharmaceuticals, Inc.
- HanAll BioPharma Co., Ltd.
- Hanlim Pharm. Co., Ltd.
- Huons Co.,Ltd.
- Kissei Pharmaceuticals
- Kala Pharmaceuticals, Inc.
- Lantibio
- Mimetogen Pharmaceuticals USA, Inc.
- Mitotech, SA
- Ocular Technologies SARL
- OmegaD LLC
- Physician Recommended Nutriceuticals
- RegeneRx Biopharmaceuticals, Inc.
- Seikagaku Corporation
- Sponsor GmbH
- Topivert Pharma Ltd
- Chong Kun Dang Pharmaceutical
- Daewoong Pharmaceutical Co. LTD.
- Otsuka
- +39 more
Organization Involved with Phase 2 Indications (63)
- R-Tech Ueno
- Abbott
- Kowa
- Genentech
- Pfizer
- Palatin Technologies
- Alacrity Biosciences, Inc.
- Aerie Pharmaceuticals
- AVX Pharma
- Croma-Pharma GmbH
- Dhp Korea Co., Ltd.
- Dong-A Pharmaceutical
- GL Pharm Tech Corporation
- Herantis Pharma Plc.
- InSite Vision
- Parion Sciences
- Rhodes Pharmaceuticals, L.P.
- Rigel Pharmaceuticals
- Samjin Pharmaceutical Co., Ltd.
- Resolvyx Pharmaceuticals, Inc
- Winston Laboratories
- Xigen SA
- Price Vision Group
- Ariel University
- Duke University
- Kresge Eye Institute
- Michigan Cornea Consultants, PC
- National University of Malaysia
- Oregon Health and Science University
- University of Michigan
- +33 more
Organization Involved with Phase 1 Indications (7)
Organization Involved with Other Experimental Indications (37)
- Aromtech Ltd.
- Eyeon Therapeutics, Inc.
- Tissue Tech Inc.
- Trima, Israel Pharmaceutical Products
- Aston University
- Baylor University
- Chung Shan Medical University
- China Academy of Chinese Medical Sciences
- Mahidol University
- Panhandle Eye Group, LLP
- University of Seville
- University of South Carolina
- Chonbuk National University
- Wenzhou Medical University
- University of Turku
- Medical University of South Carolina
- University of Indonesia
- Hebrew University
- Pennsylvania State University
- Tianjin University
- Soonchunhyang University
- Stiltec Pty Ltd
- Government of Australia
- TearLab Corporation
- The Finnish Funding Agency for Technology and Innovation
- Chonnam National University
- Nordic Naturals
- GRAPE KING
- The American Society of Cataract and Refractive Surgery Foundation
- Turku Municipal Health Department/evo-funding
- +7 more