castor oil
Botanicalexperimental
Castor oil is a vegetable oil pressed from castor beans, the seeds of the plant Ricinus communis. The seeds are 40 to 60 percent oil. It is a colourless or pale yellow liquid with a distinct taste and odor. Its boiling point is 313 °C (595 °F) and its density is 0.961 g/cm3. It includes a mixture of triglycerides in which about 90 percent of fatty acids are ricinoleates. Oleic acid and linoleic acid are the other significant components. — Wikipedia
Clinical trial activity
19 trials · 19 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
7
Phase 3
2
Phase 4
1
Earliest trial started Feb 1, 2006 (NCT00244738)
Timeline
Indications
Approved for
Studied for
- Delivery, Obstetric · Phase 2/Phase 3
- Dry Eye Syndromes · Phase 4
- Healthy Volunteers · Phase 1
- Hypogonadism · Phase 2/Phase 3
- Infant, Premature · Phase 2
- Infertility, Male · Phase 2/Phase 3
- Klinefelter Syndrome · Phase 2/Phase 3
- Pregnancy Complications · Phase 1/Phase 2
- Pressure Ulcer · Phase 2
- Sjogren's Syndrome · Phase 4
- Spinal Cord Injuries · Phase 2
- Wounds and Injuries · Phase 2
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaCastor oil ↗
- NCATSD5340Y2I9G ↗
- ChEMBLCHEMBL2109005 ↗
Also known as
- castor oil
- castor oil
- castor oil
- castor oil
- castor oil
- castor oil, aromatic
- oleum ricini
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT05723900 | N/A | Sep 15, 2022 | Tanta University |
| NCT05013151 | N/A | Aug 24, 2021 | Clalit Health Services, Technion University |
| NCT06841939 | N/A | Mar 5, 2021 | Federal Teaching Hospital Abakaliki |
| NCT03958981 | N/A | Jun 15, 2019 | Cairo University |
| NCT04807543 | Phase 2 | Jan 10, 2018 | Ain Shams University |
| NCT02615912 | N/A | Nov 30, 2015 | Kimberly Clark, RCTS, Inc. |
| NCT02004067 | Phase 4 | Jan 1, 2013 | Allergan, University of Sao Paulo |
| NCT01119963 | Phase 2/Phase 3 (Phase 3) | Oct 1, 2011 | Obstetrix Medical Group |
| NCT01433159 | Phase 2 | Sep 1, 2011 | Healthpoint |
| NCT01273428 | Phase 2 | Dec 3, 2010 | Healthpoint |
| NCT01050647 | Phase 1/Phase 2 (Phase 2) | Feb 1, 2010 | Stanford University |
| NCT01206270 | Phase 2/Phase 3 (Phase 3) | Jun 1, 2009 | University of Roma La Sapienza |
| NCT00714519 | Phase 2 | Jul 1, 2008 | Healthpoint |
| NCT00713349 | Phase 2 | Jun 1, 2008 | Healthpoint, Wake Forest University |
| NCT01732744 | N/A | Mar 31, 2008 | Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo |
| NCT00645164 | Phase 1 | Mar 1, 2008 | Eurofins, Healthpoint |
| NCT00644917 | Phase 1 | Feb 1, 2008 | Healthpoint |
| NCT00141908 | Phase 2 | Oct 1, 2006 | American University of Beirut |
| NCT00244738 | N/A | Feb 1, 2006 | Hebrew University |
Showing 19 of 19 trials
Page 1 / 1
Organizations
Research & Development (19)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Healthpoint | For profit | 6 | 6 | 2 | 2008 |
| University of Sao Paulo | Academic/Hospital | 2 | 2 | 2 | 2008 |
| Ain Shams University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Allergan | For profit | 1 | 0 | 1 | 2013 |
| American University of Beirut | Academic/Hospital | 1 | 1 | 1 | 2006 |
| Cairo University | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Clalit Health Services | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Eurofins | For profit | 1 | 0 | 1 | 2008 |
| Federal Teaching Hospital Abakaliki | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Fundação de Amparo à Pesquisa do Estado de São Paulo | Academic/Hospital | 1 | 0 | 1 | 2008 |
| Hebrew University | Academic/Hospital | 1 | 1 | 1 | 2006 |
| Kimberly Clark | For profit | 1 | 1 | 1 | 2015 |
| Obstetrix Medical Group | Academic/Hospital | 1 | 1 | 1 | 2011 |
| RCTS, Inc. | For profit | 1 | 0 | 1 | 2015 |
| Stanford University | Academic/Hospital | 1 | 1 | 1 | 2010 |
| Tanta University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Technion University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Roma La Sapienza | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Wake Forest University | Academic/Hospital | 1 | 0 | 1 | 2008 |
19 organizations
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