terpinen-4-ol
Small moleculeexperimental
Terpinen-4-ol is an isomer of terpineol with the chemical formula C10H18O. A primary constituent of tea tree oil, it is obtained as an extract from the leaves, branches, and bark of Melaleuca alternifolia Cheel. Despite considerable basic and preliminary clinical research of terpinen-4-ol and tea tree oil, its biological properties and potential for clinical uses have not been established as of 2019. It may be a factor in the contact dermatitis of tea tree oil when used topically. — Wikipedia
Clinical trial activity
3 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
1
Earliest trial started Feb 1, 2014 (NCT01647217)
Timeline
2010s
- Jan 1, 2014
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Studied for
Mechanism of action
- Cell membraneDISRUPTING AGENT
Cell membrane disrupting agent
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaTerpinen-4-ol ↗
Also known as
- (r)-1-isopropyl-4-methyl-3-cyclohexen-1-ol
- terpinen-4-ol
- terpinen-4-ol
- terpinen-4-ol
- terpinen-4-ol
- terpinenol-4
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03987230 | N/A | May 29, 2019 | University of Waterloo |
| NCT04441528 | Phase 4 | Nov 1, 2018 | Istanbul University, Koç University |
| NCT01647217 | Phase 1 | Feb 1, 2014 | National Eye Institute (NEI), Tissue Tech Inc. |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Istanbul University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Koç University | Academic/Hospital | 1 | 0 | 1 | 2018 |
| National Eye Institute (NEI) | Government | 1 | 0 | 1 | 2014 |
| Tissue Tech Inc. | For profit | 1 | 1 | 1 | 2014 |
| University of Waterloo | Academic/Hospital | 1 | 1 | 1 | 2019 |
5 organizations
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