diquafosol
Small moleculeexperimental
Diquafosol is a pharmaceutical drug for the treatment of dry eye disease. It was approved for use in Japan in 2010. It is formulated as a 3% ophthalmic solution of the tetrasodium salt. — Wikipedia
Clinical trial activity
14 trials · 12 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
5
Phase 3
3
Phase 4
2
Earliest trial started Aug 15, 2017 (NCT03640351)
Timeline
Indications
Approved for
Mechanism of action
- Purinergic receptor P2Y2AGONIST
P2RY2 agonist
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaDiquafosol ↗
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06903884 | Phase 3 | Dec 30, 2025 | The University of Hong Kong |
| NCT07097922 | N/A | Aug 1, 2025 | He Eye Hospital |
| NCT06852105 | N/A | Feb 28, 2025 | He Eye Hospital |
| NCT06427031 | Phase 3 | Jul 14, 2023 | Taejoon Pharm Co., Ltd. |
| NCT07297316 | Phase 4 | Oct 3, 2022 | Korea University, Kukje Pharma |
| NCT06146881 | Phase 2 | Oct 2, 2022 | Santen Inc., University of Indonesia |
| NCT05383612 | N/A | Aug 5, 2022 | — |
| NCT06560580 | N/A | Nov 15, 2021 | Tianjin Eye Hospital |
| NCT05346783 | Phase 1/Phase 2 (Phase 2) | Oct 14, 2021 | Taejoon Pharm Co., Ltd., Yonsei University |
| NCT04668118 | Phase 4 | Jan 1, 2021 | Peking University |
| NCT04548427 | Phase 3 | Aug 18, 2020 | Chong Kun Dang Pharmaceutical, Pusan National University |
| NCT05456061 | N/A | Aug 1, 2018 | Yonsei University |
| NCT03216096 | Phase 1 | Sep 8, 2017 | Santen Inc. |
| NCT03640351 | N/A | Aug 15, 2017 | Yonsei University |
Showing 14 of 14 trials
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Organizations
Research & Development (12)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Yonsei University | Academic/Hospital | 3 | 2 | 2 | 2017 |
| He Eye Hospital | Academic/Hospital | 2 | 2 | 1 | 2025 |
| Santen Inc. | For profit | 2 | 1 | 2 | 2017 |
| Taejoon Pharm Co., Ltd. | For profit | 2 | 2 | 2 | 2021 |
| Chong Kun Dang Pharmaceutical | For profit | 1 | 1 | 1 | 2020 |
| Korea University | Academic/Hospital | 1 | 1 | 1 | 2022 |
| Kukje Pharma | For profit | 1 | 0 | 1 | 2022 |
| Peking University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Pusan National University | Academic/Hospital | 1 | 0 | 1 | 2020 |
| The University of Hong Kong | Academic/Hospital | 1 | 1 | 1 | 2025 |
| Tianjin Eye Hospital | Academic/Hospital | 1 | 1 | 1 | 2021 |
| University of Indonesia | Academic/Hospital | 1 | 1 | 1 | 2022 |
12 organizations
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