← All indications
Osteoarthritis, Knee
Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
Drugs by status
Phase 4 trials (89)
- tranexamic acid
- ferrous sulfate
- morphine
- levobupivacaine
- ibuprofen
- bupivacaine
- lidocaine
- rimabotulinumtoxinB
- aminocaproic acid
- urea
- threonate
- remimazolam
- phosphatidylcholine
- fentanyl
- imrecoxib
- sodium chloride
- rivaroxaban
- guli
- capsaicin
- aceclofenac
- magnesium sulfate
- dextrose
- ramosetron
- epinephrine
- midazolam
- hydrocortisone
- spironolactone
- methylprednisolone
- spearmint
- curcuma longa
- +59 more
Phase 3 trials (85)
- dulaglutide
- glucose monohydrate
- pk101
- hu-qian wan
- umbilical cord mesenchymal stem cells
- huangqi
- autologous serum
- traumeel
- tramadol
- zucapsaicin
- collagen
- hydrocodone
- panlongqi
- hydromorphone
- tongbi
- ozone
- Aspartyl-alanyl-diketopiperazine
- ketoprofen
- adalimumab
- skcpt
- baclofen
- citrus reticulata
- pentosan polysulfate sodium
- resveratrol
- Honeybee venom
- buprenorphine
- oxycodone
- sorbitol
- wobenzyme
- sinomenine
- +55 more
Phase 2 trials (111)
- pf-04191834
- bee venom
- levi-04
- fasitibant
- miv-711
- tafamidis
- oxygen
- talc
- lna043
- krill oil
- somatropin
- maltodextrin
- ib-meca
- asp7962
- ly3526318
- methotrexate
- allocetra-ots
- adl5859
- Dapansutrile
- human dehydrated amnion chorion allograft
- devil claw
- ly3857210
- tetracaine
- galcanezumab-gnlm
- peripheral blood mesenchymal stem cells
- yy1201
- oxycodegol
- win34b
- rhh646
- benjakul
- +81 more
Phase 1 trials (33)
- 131i-lipiodol
- autologous hematopoietic stem cells
- bbm-a101
- exosomes from mesenchymal stem cells
- cyt-108
- 99mtc-ntp 15-5
- cell-free stem cell-derived extract formulation (ccm)
- allogenic amniotic fluid mesenchymal stem cell
- curcumin
- copper
- devil's claw
- psc-01
- chicken extract
- askc200
- Resiniferatoxin
- 4p-004
- ka34
- dental pulp mesenchymal stem cells
- human choriogonadotropin alfa
- allogeneic engineered gingival fibroblasts
- humantakinogene hadenovec
- mavatrep
- op-1
- sc-raav2.5il-1ra
- platelet poor plasma
- warfarin
- umc119-06-05
- cortisone acetate
- parabens
- pg110
- +3 more
Other trials (56)
- cyclizine lactate
- polycan
- bifidobacterium animalis
- raspberry
- lornoxicam
- etanercept
- water
- vitamin e
- whey protein
- lithothamnion
- 99mtc ec20
- tenoxicam
- egg
- fennugreek
- allogenic mesenchymal stem cells derived exosome enriched by mir-124
- strawberry
- solgar no7 complex
- du-huo-ji-sheng-tang
- blueberry
- flurbiprofen
- ethanol
- xinfeng
- pb125
- lanconone
- desflurane
- Andrographis paniculata
- bergamot oil
- autologous activated lymphocyte
- vitamin c
- cord blood hematopoietic stem cell
- +26 more
Organizations
Organization Involved with Phase 4 Indications (141)
- PMG Pharm Co., Ltd
- Vifor Inc.
- Ruhr University Bochum
- Guizhou Medical University
- Peking University
- University of Zurich
- University of Oslo
- Tufts University
- Government Medical College, Amritsar
- Chong Kun Dang Pharmaceutical
- Virginia Commonwealth University
- Wake Forest University
- National Taiwan University
- University of Montreal
- Ajou University
- Thammasat University
- University of Miami
- Region Syddanmark
- University of Sydney
- Hospital dos Servidores do Estado - Rio de Janeiro
- University of Ulsan
- Magna Graecia University
- Shin Kong Wu Ho-Su Memorial Hospital
- University of Copenhagen
- Rush University
- Capital Medical University
- Indus Hospital
- Artroclinica de Fortaleza
- Lynk Biotechnologies Pte Ltd
- ArthroBiologix Inc.
- +111 more
Organization Involved with Phase 3 Indications (157)
- Shionogi
- Mashhad University of Medical Sciences
- Blair Orthopedic Associates, Inc
- Biologische Heilmittel Heel GmbH
- University of Lausanne
- Rottapharm
- Novartis
- LG
- CAPRI Clinic
- Centre de Rhymatologie St-Louis
- Clinical Research Solutions
- Alza
- Hospital Universitario Central de Asturias
- Iroko
- Nature Cell Co. Ltd.
- Novum Pharmaceutical Research Services
- Taisho Pharmaceutical
- IBSA Institut Biochimique SA
- ArthroLab Inc.
- KhonKaen University
- Physician Recommended Nutriceuticals
- Arthritis Treatment Center, Maryland
- Nuvo Research Inc.
- Carbylan Therapeutics, Inc.
- PMG Research
- TissueGene, Inc.
- NicOx
- Bone Therapeutics S.A
- Anika Therapeutics, Inc.
- University of Oxford
- +127 more
Organization Involved with Phase 2 Indications (167)
- Pure Green, LLC
- Allergan
- Cara Therapeutics
- University of Lille
- ESBATech AG
- Anupam Hospital
- Swisse Wellness Pty Ltd
- UnicoCell Biomed CO. LTD
- Sclnow Biotechnology Co., Ltd.
- Medivir
- Procter and Gamble
- University of Rochester
- Can-Fite BioPharma
- University of Strasbourg
- Avail Clinical Research
- The Institute of Traumatology and Orthopedics of NAMS of Ukraine
- Medical University of Warsaw
- University of Adelaide
- Northwell Health
- Kyiv City Clinical Hospital № 6
- Virginia Hospital Center
- Linkoping University
- Stanford University
- Taipei Veteran General hospital
- Mucos Pharma GmbH and Co
- Galapagos NV
- Universidad Autonoma de Nuevo Leon
- University Health Network, Toronto
- Eupraxia Pharmaceuticals
- Rehasport Clinic
- +137 more
Organization Involved with Phase 1 Indications (48)
- Medical Pain Consultants
- Stem Cells Arabia
- The Danish Rheumatism Association
- Plastic Surgery Education and Research Foundation
- University of North Carolina at Chapel Hill
- Reiley Pharmaceuticals Inc.
- SGS Life Sciences
- Mestex AG
- Stemedica
- Changhai Hospital
- Isfahan University
- Q-Med AB
- Regenexx
- Chinese University of Hong Kong
- Foundation for Physical Medicine and Rehabilitation
- EMO Biomedicine Corp.
- Steminent Biotherapeutics Inc.
- Southeast University
- ZetrOZ, Inc.
- CAR-T (Shanghai) Biotechnology Co.,Ltd.
- 3VM Research Group, Inc.
- University of Missouri
- Loma Linda University
- Biomet
- Merck KGaA
- University of Indonesia
- Amgen
- Hospital for Special Surgery, New York
- Covance
- Abbott
- +18 more
Organization Involved with Other Experimental Indications (96)
- Arthritis and Osteoporosis Center of Maryland
- Zhejiang Chinese Medical University
- Hôpital Roger Salengro
- Foundation University Institute of Rehabilitation Sciences
- Association of Danish Physiotherapists
- Avanos Medical
- Vietstar Biomedical Research
- Enovate Biolife Pvt Ltd
- University of British Columbia
- Towson Orthopaedic Associates
- Analgesic Solutions
- Huazhong University of Science and Technology
- Government Medical College, Bhavnagar
- Optimum Contract Research Organisation
- National Yang-Ming University
- AmeRuss Clinical Trials LLC, USA
- Allegiance Health
- Red Cross Hospital, Hangzhou, China
- Changi General Hospital
- Vedic Lifesciences Pvt. Ltd.
- Harbin Medical University
- The Foundation for Sports Medicine and Arthritis Research
- University of Nottingham
- Kaohsiung Medical University
- Sun Valley Arthritis Ltd, Glendale
- Bronx Lebanon Hospital Center
- University of Helsinki
- Yerkoy State Hospital
- University of Oklahoma
- Bezmialem University
- +66 more