Andrographis paniculata
Botanicalexperimental
Andrographis paniculata, commonly known as creat or green chiretta, is an annual herbaceous plant in the family Acanthaceae, native to India and Sri Lanka. — Wikipedia
Clinical trial activity
21 trials · 36 clinical orgs · 0 marketing orgs
Phase 1
4
Phase 2
10
Phase 3
6
Phase 4
4
Earliest trial started Apr 1, 2006 (NCT00655733)
Timeline
Indications
Approved for
Studied for
- Bronchitis · Phase 4
- Colitis, Ulcerative · Phase 3
- Colorectal Neoplasms · Phase 2
- Community-Acquired Infections · Phase 4
- COVID-19 · Phase 3
- Crohn Disease · Phase 2
- Esophageal Neoplasms · Phase 3
- Molecular Mechanisms of Pharmacological Action · Phase 1
- Multiple Sclerosis, Chronic Progressive · Phase 1/Phase 2
- Multiple Sclerosis, Relapsing-Remitting · Phase 1/Phase 2
- Pharmacokinetics · Phase 1
- Respiratory Tract Infections · Phase 3
- Tonsillitis · Phase 4
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaAndrographis paniculata ↗
- NCATS0P49L952WZ ↗
- WikipediaAndrographolide ↗
Also known as
- andrographis
- andrographis
- andrographis paniculata extract
- andrographolide
- andrographolide
- andrographolide sulfonate
- hmpl004
- hmpl-004
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06520527 | N/A | Jul 21, 2024 | Universitas Palangka Raya |
| NCT05019326 | Phase 3 | Aug 30, 2021 | Government of Thailand, Mahidol University |
| NCT04847518 | Phase 2/Phase 3 (Phase 3) | May 26, 2021 | Phytomed AB, Swedish Herbal Institute AB, Tbilisi State Medical University |
| NCT04955327 | Phase 3 | Mar 20, 2021 | Vedic Lifesciences Pvt. Ltd. |
| NCT04833946 | N/A | Mar 13, 2021 | Vedic Lifesciences Pvt. Ltd. |
| NCT04161404 | Phase 1 | Aug 21, 2019 | Government of Malaysia, University of Malaya |
| NCT03597971 | Phase 1 | Mar 20, 2018 | Hutchison MediPharma, Nestle, Nutrition Science Partners Limited |
| NCT04196075 | Phase 3 | Mar 1, 2018 | Chinese University of Hong Kong |
| NCT03262792 | N/A | Dec 13, 2017 | Vedic Lifesciences Pvt. Ltd. |
| NCT03190044 | N/A | Jun 6, 2017 | University of Roma La Sapienza |
| NCT03134443 | Phase 4 | Dec 1, 2016 | Nanchang University, Qingfeng Pharmaceutical Group |
| NCT03132610 | Phase 4 | Dec 1, 2016 | Nanchang University, Qingfeng Pharmaceutical Group |
| NCT03132623 | Phase 4 | Dec 1, 2016 | First Hospital of Shijiazhuang City, Gannan Medical University, Jiujiang First People's Hospital, Nanchang University, Qingfeng Pharmaceutical Group |
| NCT02913118 | Phase 4 | Jul 1, 2016 | Capital Medical University, China Medical University, First Hospital of QinHuangDao, Hebei University, Nanchang University, Peking University, People's Liberation Army of China, Qingdao Municipal Hospital, Qingfeng Pharmaceutical Group, Shanxi Medical University, Sichuan University, The Central Hospital of ZiBo City, Tianjin Medical University, Wenzhou Medical University |
| NCT02273635 | Phase 1/Phase 2 (Phase 2) | Sep 1, 2014 | Innobioscience SpA, Pontificia Universidad Catolica de Chile, Universidad Austral de Chile, University of Chile |
| NCT01993472 | Phase 2 | Nov 1, 2013 | Nanjing Medical University |
| NCT01882764 | Phase 3 | Jun 1, 2013 | Hutchison MediPharma, Nutrition Science Partners Limited |
| NCT01805791 | Phase 3 | Mar 1, 2013 | Hutchison MediPharma |
| NCT02280876 | Phase 1/Phase 2 (Phase 2) | Jan 1, 2012 | Universidad Austral de Chile, University of Chile |
| NCT00659802 | Phase 2 | Mar 1, 2008 | Hutchison MediPharma |
Showing 20 of 21 trials
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Organizations
Research & Development (36)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Hutchison MediPharma | For profit | 5 | 4 | 3 | 2006 |
| Nanchang University | Academic/Hospital | 4 | 0 | 1 | 2016 |
| Qingfeng Pharmaceutical Group | For profit | 4 | 4 | 1 | 2016 |
| Vedic Lifesciences Pvt. Ltd. | For profit | 3 | 3 | 2 | 2017 |
| Nutrition Science Partners Limited | For profit | 2 | 1 | 2 | 2013 |
| Universidad Austral de Chile | Academic/Hospital | 2 | 1 | 1 | 2012 |
| University of Chile | Academic/Hospital | 2 | 0 | 1 | 2012 |
| Capital Medical University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| China Medical University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Chinese University of Hong Kong | Academic/Hospital | 1 | 1 | 1 | 2018 |
| First Hospital of QinHuangDao | Academic/Hospital | 1 | 0 | 1 | 2016 |
| First Hospital of Shijiazhuang City | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Gannan Medical University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Government of Malaysia | Government | 1 | 0 | 1 | 2019 |
| Government of Thailand | Government | 1 | 0 | 1 | 2021 |
| Hebei University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Innobioscience SpA | For profit | 1 | 1 | 1 | 2014 |
| Jiujiang First People's Hospital | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Mahidol University | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Nanjing Medical University | Academic/Hospital | 1 | 1 | 1 | 2013 |
36 organizations
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