galcanezumab-gnlm

Trade name: emgality

mAbapproved

Approved

Sep 27, 2018

Galcanezumab, sold under the brand name Emgality, is a humanized monoclonal antibody used for the prevention of migraine. It is also used for the treatment of cluster headaches. — Wikipedia

Clinical trial activity

30 trials · 8 clinical orgs · 1 marketing orgs

Phase 1
6
Phase 2
17
Phase 3
12
Phase 4
7

Earliest trial started Apr 1, 2011 (NCT01337596)

Timeline

2010s

  1. Jan 1, 2011

    Eli Lilly — Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2012

    Eli Lilly — Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2015

    Eli Lilly — Earliest Phase 3 Sponsor(trial)

  4. Sep 27, 2018

    Eli Lilly — Earliest FDA Approval

  5. Sep 27, 2018

    Eli Lilly — Marketing Organization

  6. Sep 27, 2018

    Eli Lilly — NDA Organization

Indications

Mechanism of action

Approval history

  • approvedSep 27, 2018

Chemistry & pharmacology

Chirality
Single Stereoisomer
Inorganic
No
Polymer
No
Delivery
Parenteral
Multi-specific
No

Oral

No

Parenteral

Yes

Topical

No

Sources

Also known as

  • galcanezumab
  • galcanezumab
  • galcanezumab-gnlm
  • ly2951742
  • ly-2951742

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT05492695Phase 4Oct 1, 2022Diamond Headache Clinic
NCT05284019Phase 4Mar 4, 2022Lundbeck
NCT05127486Phase 4Nov 18, 2021Eli Lilly
NCT04616326Phase 3Nov 25, 2020Eli Lilly
NCT06901518Phase 4Aug 10, 2020Albany Medical College, Eli Lilly
NCT04417361Phase 2Jul 1, 2020Eli Lilly, University of California, San Francisco
NCT04294147Phase 4Mar 17, 2020Eli Lilly
NCT04271202Phase 4Mar 1, 2020Eli Lilly, Harvard University
NCT04158752Phase 4Dec 31, 2019Duke University, Eli Lilly
NCT04085289Phase 1Nov 14, 2019Eli Lilly
NCT04179474Phase 1Sep 26, 2019Allergan
NCT03963232Phase 3Jul 31, 2019Eli Lilly
NCT03559257Phase 3Jul 31, 2018Eli Lilly
NCT03432286Phase 3Mar 14, 2018Eli Lilly
NCT02959190Phase 3Feb 7, 2017Eli Lilly
NCT02959177Phase 2Nov 1, 2016Eli Lilly
NCT02836613Phase 1Jul 1, 2016Eli Lilly
NCT02797951Phase 3Jul 1, 2016Eli Lilly
NCT02614196Phase 3Dec 1, 2015Eli Lilly
NCT02614183Phase 3Nov 1, 2015Eli Lilly
Showing 20 of 30 trials
Page 1 / 2

Organizations

Research & Development (8)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
Eli LillyFor profit272342011
Albany Medical CollegeAcademic/Hospital1112020
AllerganFor profit1112019
Diamond Headache ClinicAcademic/Hospital1112022
Duke UniversityAcademic/Hospital1112019
Harvard UniversityAcademic/Hospital1112020
LundbeckFor profit1112022
University of California, San FranciscoAcademic/Hospital1112020
8 organizations
Page 1 / 1

Marketing (2)

OrganizationOrg typeRelationshipDate
Eli LillyFor profitMKTGSep 27, 2018
Eli LillyFor profitNDASep 27, 2018