Alcoholism
A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Drugs by status
Approved for this indication (6)
Phase 4 trials (46)
- propofol
- acetylcysteine
- paroxetine
- lamotrigine
- chlorzoxazone
- clozapine
- methylphenidate
- valproic acid
- ethanol
- escitalopram
- sertraline
- sodium oxybate
- carbamazepine
- lorazepam
- levetiracetam
- topiramate
- fluoxetine
- dronabinol
- memantine
- oxazepam
- acetaminophen
- prazosin
- nicotine
- dutasteride
- ribavirin
- risperidone
- spironolactone
- diazepam
- thiamine
- zonisamide
- +16 more
Phase 3 trials (22)
Phase 2 trials (82)
- mifepristone
- 123i-iodobenzamide
- samidorphan
- abt-436
- brexpiprazole
- lorcaserin
- carisbamate
- apremilast
- citalopram
- diphenhydramine
- exenatide
- cp-866,087
- cyproheptadine
- duloxetine
- suvorexant
- perampanel
- gemfibrozil
- glwl-01
- glycine
- guanfacine
- bone marrow derived mesenchymal stem cells
- insulin human
- ibudilast
- iomazenil (123i)
- ivermectin
- kudzu extract
- ly2940094
- tradipitant
- m-chlorophenylpiperazine
- verucerfont
- +52 more
Phase 1 trials (25)
Other trials (26)
- (s,s)-[11c]mrb
- phno
- omar
- beetroot juice
- cycloserine
- liraglutide
- levodopa
- inulin
- caffeine
- rimonabant
- sulfasalazine
- thiopental
- anke malz
- avmacol
- bifidobacterium bifidum
- lactobacillus plantarum
- zinc dichloride
- bacillus coagulans
- amphetamine
- Lactobacillus acidophilus
- lactobacillus casei
- olive
- ketone monoester
- s-adenosyl methionine
- lactobacillus delbrueckii
- lactobacillus
Organizations
Organization Involved with Phase 4 Indications (92)
- Cephalon
- Bristol-Myers Squibb
- Forest Laboratories
- AstraZeneca
- Merck
- Eli Lilly
- Novartis
- Alkermes
- Laboratorio Farmaceutico Ct S.r.l.
- Otsuka
- Finnish Foundation for Alcohol Studies
- National Center for Research Resources (NCRR)
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- United States Army
- Aarhus University
- University of Pennsylvania
- University of Pittsburgh
- Augusta University
- Boston University
- CAMC Health System
- Harvard University
- Dartmouth University
- Federal University of Rio Grande do Sul
- University of Washington
- Hoosier Cancer Research Network
- Indiana University
- Johns Hopkins University
- Mbarara University of Science and Technology
- Mclean Hospital
- New York University
- +62 more
Organization Involved with Phase 3 Indications (32)
- Abbott
- Ethypharm
- R-Pharm
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Research Foundation for Mental Hygiene, Inc.
- National Institute on Drug Abuse (NIDA)
- Brown University
- Chulalongkorn University
- National Cheng Kung University
- Norwegian University of Science and Technology
- Oregon Health and Science University
- The Mind Research Network
- University of Houston
- University of Maryland
- University of Bern
- University of Virginia
- Associacao Fundo de Incentivo a Psicofarmcologia
- South West Sydney Local Health District
- University of California, San Diego
- Macquarie University
- Sydney Local Health District
- University of Sao Paulo
- University of Nantes
- Synergy Research
- University of Paris
- Humboldt University
- Technical University of Dresden
- University of Picardie Jules Verne
- Lade Addiction Treatment Center
- Princess Mother National Institute on Drug Abuse and Treatment
- +2 more
Organization Involved with Phase 2 Indications (58)
- AbbVie
- XenoPort, Inc.
- MediciNova
- Pfizer
- Amygdala Neurosciences, Inc.
- Bioprojet
- Neumora Therapeutics, Inc.
- Indivior Inc.
- Minnesota Veterans Medical Research and Education Foundation
- National Institutes of Health (NIH)
- National Center for Complementary and Integrative Health (NCCIH)
- National Institute of Mental Health (NIMH)
- Vastra Gotaland Region
- Baylor University
- University of London
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Essentia Health
- Emory University
- Hanyang University
- John Wayne Cancer Institute
- Malmö University
- Melbourne Health
- Michigan State University
- Northwell Health
- Rhode Island Hospital
- RTI International
- University of Florida
- University of Zurich
- Stony Brook University
- University of Colorado, Denver
- +28 more
Organization Involved with Phase 1 Indications (15)
- GlaxoSmithKline
- RWTH Aachen University
- University of Kentucky
- University of Rhode Island
- University of Cambridge
- Battelle
- OpenBiome
- CEDRA Clinical Research
- Pennsylvania State University
- National Center for Advancing Translational Science (NCATS)
- Carnegie Mellon University
- University of Texas, Austin
- Imperial College London
- IQVIA
- Pop Test Oncology LLC
Organization Involved with Other Experimental Indications (14)
- University of Illinois
- University of Georgia
- University of Michigan
- University of Oklahoma
- Utrecht University
- Yonsei University
- Tel Aviv University
- University of California, Berkeley
- University of Chicago
- Université catholique de Louvain
- Hospital Universitari General de Catalunya
- University of Barcelona
- Canadian Institutes of Health Research (CIHR)
- Steno Diabetes Center Copenhagen