nop-1a
Small moleculeexperimentalImaging agent
Clinical trial activity
3 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Sep 3, 2010 (NCT01198197)
Timeline
2010s
- Jan 1, 2010
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
- Unspecified targetRadiopharmaceutical
radiopharmaceutical
Chemistry & pharmacology
Loading structure…
SMILES
CNC(=O)[C@@H](Cc1ccccc1F)CN1CCC2(CC1)OCCc1cc(F)sc12- Mol. weight
- 420.53 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
- Imaging
- 11-carbon
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL2088033 ↗
Also known as
- nop-1a
- nop-1a
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03448016 | Early Phase 1 (Phase 1) | May 27, 2016 | National Institute on Alcohol Abuse and Alcoholism (NIAAA), University of Pittsburgh |
| NCT03348384 | Early Phase 1 (Phase 1) | Oct 30, 2014 | National Institute on Drug Abuse (NIDA), University of Pittsburgh |
| NCT01198197 | Early Phase 1 (Phase 1) | Sep 3, 2010 | National Institute of Mental Health (NIMH) |
Showing 3 of 3 trials
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Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Pittsburgh | Academic/Hospital | 2 | 2 | 1 | 2014 |
| National Institute of Mental Health (NIMH) | Government | 1 | 1 | 1 | 2010 |
| National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Government | 1 | 0 | 1 | 2016 |
| National Institute on Drug Abuse (NIDA) | Government | 1 | 0 | 1 | 2014 |
4 organizations
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