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Hypoglycemia
A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
Subtype terms (2)
More specific conditions that are subtypes of Hypoglycemia in the MeSH hierarchy.
- Congenital Hyperinsulinism
17 drugs (13 approved, 4 experimental)
- Insulin Coma
Drugs by status
Approved for this indication (3)
Phase 4 trials (27)
- levofloxacin
- diazoxide
- betamethasone
- empagliflozin
- ethanol
- insulin glargine
- glimepiride
- liraglutide
- acarbose
- glucomannan
- insulin human
- insulin degludec
- insulin detemir
- pasireotide
- cow milk
- pramlintide
- glucose
- spironolactone
- verapamil
- vildagliptin
- ciprofloxacin
- insulin lispro
- naloxone
- sufonylurea
- dapagliflozin
- lactic acid
- dextrose
Phase 2 trials (29)
- vitamin d3
- amitriptyline
- acetylcysteine
- daclizumab
- efalizumab
- etanercept
- fluorodopa
- tacrolimus
- naltrexone
- aldesleukin
- Filgrastim
- metoclopramide
- sirolimus
- cyclosporine
- exendin (9-39)
- everolimus
- Anti-thymocyte Globulin (Rabbit)
- gevokizumab
- xoma 358
- carvedilol
- glucagon-like peptide-1
- teplizumab
- sodium chloride
- anakinra
- omega-3 fatty acids
- glibenclamide
- vx-880
- opf-310
- e-islet 01
Phase 1 trials (14)
Other trials (28)
- 1-13c acetate
- maltodextrin
- beta-hydroxybutyrate
- epoetin
- candesartan
- diazoxide choline
- gip (1-42)
- nevulose
- levocarnitine
- phentolamine mesylate
- propranolol
- epinephrine
- rifaximin
- tumor necrosis factor
- glycosade
- oat bran
- oligofructose
- raspberry
- superstarch
- phytospherix
- eplerenone
- canagliflozin
- glycogen
- potassium phosphate
- glucose monohydrate
- cherry
- honeyberry
- Neuronostatin
Organizations
Organization Involved with Phase 4 Indications (36)
- Bristol-Myers Squibb
- Novo Nordisk
- Sanofi
- Novartis
- GWT-TUD GmbH
- National Institutes of Health (NIH)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Aarhus University
- Ain Shams University
- Bassett Healthcare
- Harvard University
- Institut d'Anesthesiologie des Alpes Maritimes
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Joslin Diabetes Center
- Lund University
- Newcastle University
- University of Dundee
- University of Manchester
- University of Southern Denmark
- University of Tampere
- University of Copenhagen
- Beni Suef University
- Koege University
- University of California, Riverside
- University of Nice Sophia Antipolis
- Medtronic
- University of Tuebingen
- Technical University of Denmark
- Danish Diabetes Academy
- +6 more
Organization Involved with Phase 3 Indications (11)
Organization Involved with Phase 2 Indications (31)
- Amylin
- Roche
- Eiger BioPharmaceuticals
- ViaCyte
- Xoma
- University of Pennsylvania
- Baylor University
- HealthPartners Institute
- Institut National de la Santé Et de la Recherche Médicale, France
- Johns Hopkins University
- Oregon Health and Science University
- Oxford Brookes University
- Stanford University
- Translational Research Institute for Metabolism and Diabetes, Florida
- University of Miami
- York University
- University of Utah
- University of Minnesota
- Profil GmbH
- University of Lille
- Hebrew University
- University of Oxford
- University of Montreal
- Park Nicollet
- University of Texas, San Antonio
- American Diabetes Association
- The Leona M. and Harry B. Helmsley Charitable Trust
- Emissary International LLC
- Society of Critical Care Medicine
- Diabetes Research Institute Foundation
- +1 more
Organization Involved with Phase 1 Indications (19)
- Hospira
- Fresenius
- Bayhill Therapeutics
- Biodel
- INC Research
- Zosano Pharma Inc.
- Cedars-Sinai Medical Center
- Monash University
- University of Maryland
- Yale University
- East Carolina University
- University of California, San Diego
- University of Cincinnati
- University of Colorado, Denver
- Walter and Eliza Hall Institute of Medical Research
- West Houston Clinical Research Services
- University of Barcelona
- High Point Clinical Trial Center
- Ferox Therapeutics
Organization Involved with Other Experimental Indications (33)
- European Foundation for the Study of Diabetes
- Fondazione Poliambulanza Istituto Ospedaliero
- Hillerod Hospital
- Maastricht University
- University of Manitoba
- Gottfried Wilhelm Leibniz Universität Hannover
- Hypoglycaemia Research Group
- Makerere University
- McGill University
- University of Hull
- University of Oslo
- University of Pavia
- Creighton University
- Prince of Songkla University
- University of Calgary
- University of Cambridge
- University of Naples Frederico II
- Vanderbilt University
- University of Amsterdam
- University of Malawi
- Karolinska Institute
- Erasmus University Rotterdam
- University of Western Ontario
- Mirexus Biotechnologies Inc
- Robert Wood Johnson Foundation
- Lester and Liesel Baker Foundation
- Dutch Diabetes Research Foundation
- LifeScan
- Becton Dickinson
- Pennington Biomedical Research Center
- +3 more