sufonylurea
Small moleculeexperimental
Clinical trial activity
56 trials · 57 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
31
Phase 3
29
Phase 4
16
Earliest trial started Sep 1, 2000 (NCT00006305)
Timeline
Indications
Approved for
Studied for
- Angina Pectoris · Phase 4
- Cardiovascular Diseases · Phase 4
- Coronary Artery Disease · Phase 4
- Coronary Disease · Phase 3
- Diabetes Mellitus · Phase 4
- Diabetes Mellitus, Type 1 · Phase 4
- Diabetes Mellitus, Type 2 · Phase 4
- Endocrine System Diseases · Phase 3
- Glucose Metabolism Disorders · Phase 3
- Heart Diseases · Phase 3
- Hyperglycemia · Phase 3
- Hypertension · Phase 4
- Hypoglycemia · Phase 4
- Hypoglycemic Agents · Phase 3
- Insulin Resistance · Phase 3
- Metabolic Diseases · Phase 3
- Obesity · Phase 2
- Percutaneous Coronary Intervention · Phase 4
- Proteinuria · Phase 4
- Renal Insufficiency, Chronic · Phase 3
Mechanism of action
- Sulfonylurea receptor 1INHIBITOR
ABCC8 inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- sufonylurea
- sufonylurea
- sulfonylurea
- sulfonylurea
- sulphonylurea
- sulphonylurea
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04809220 | Phase 3 | Apr 13, 2021 | Eli Lilly |
| NCT04192292 | N/A | Oct 8, 2019 | University of Dundee |
| NCT03770728 | Phase 3 | Jul 18, 2019 | Sanofi |
| NCT03761134 | Phase 3 | Nov 30, 2018 | Sanofi |
| NCT02786823 | Phase 2/Phase 3 (Phase 3) | May 1, 2017 | All India Institute of Medical Sciences |
| NCT04239586 | Phase 4 | Apr 18, 2017 | University of Bergen |
| NCT03066830 | Phase 3 | Feb 24, 2017 | Sanofi |
| NCT02941367 | Phase 4 | Feb 23, 2017 | Sanofi |
| NCT02954692 | Phase 4 | Nov 30, 2016 | Sanofi |
| NCT02686177 | Phase 4 | May 1, 2016 | University of Paris |
| NCT02730377 | Phase 4 | Mar 28, 2016 | Novo Nordisk |
| NCT03983551 | Phase 4 | Mar 1, 2016 | Changhua Christian Hospital |
| NCT02796170 | Phase 4 | Mar 1, 2016 | AstraZeneca, Tulane University |
| NCT02693392 | N/A | Jan 1, 2016 | All India Institute of Medical Sciences, Chemical Resources |
| NCT02624830 | Phase 4 | Nov 1, 2015 | Institut National de la Santé Et de la Recherche Médicale, France, University of Bergen, University of Exeter, University of Paris, University of Rome Tor Vergata |
| NCT02624817 | Phase 4 | Nov 1, 2015 | Institut National de la Santé Et de la Recherche Médicale, France, University of Bergen, University of Exeter, University of Paris, University of Rome Tor Vergata |
| NCT02532855 | Phase 3 | Oct 1, 2015 | Merck |
| NCT01917656 | Phase 4 | Jan 1, 2014 | Novo Nordisk |
| NCT02015780 | Phase 3 | Dec 1, 2013 | Takeda |
| NCT02027753 | Phase 4 | Dec 1, 2013 | Sanofi |
Showing 20 of 56 trials
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Organizations
Research & Development (57)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Sanofi | For profit | 10 | 9 | 2 | 2008 |
| Novo Nordisk | For profit | 5 | 4 | 2 | 2006 |
| Eli Lilly | For profit | 4 | 4 | 1 | 2011 |
| GlaxoSmithKline | For profit | 4 | 3 | 2 | 2001 |
| Merck | For profit | 4 | 3 | 2 | 2010 |
| University of Bergen | Academic/Hospital | 4 | 3 | 2 | 2004 |
| University of Paris | Academic/Hospital | 4 | 1 | 2 | 2004 |
| Johnson and Johnson | For profit | 3 | 3 | 1 | 2010 |
| University of Exeter | Academic/Hospital | 3 | 1 | 2 | 2004 |
| All India Institute of Medical Sciences | Academic/Hospital | 2 | 2 | 2 | 2016 |
| AstraZeneca | For profit | 2 | 1 | 2 | 2007 |
| Bristol-Myers Squibb | For profit | 2 | 0 | 1 | 2007 |
| Harvard University | Academic/Hospital | 2 | 0 | 2 | 2012 |
| Institut National de la Santé Et de la Recherche Médicale, France | Academic/Hospital | 2 | 0 | 1 | 2015 |
| Mitsubishi Tanabe | For profit | 2 | 2 | 1 | 2009 |
| National Heart, Lung, and Blood Institute (NHLBI) | Government | 2 | 0 | 1 | 2000 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Government | 2 | 0 | 1 | 2000 |
| University of Rome Tor Vergata | Academic/Hospital | 2 | 0 | 1 | 2015 |
| University of Tokyo | Academic/Hospital | 2 | 0 | 1 | 2009 |
| Associazione Medici Diabetologi (AMD) | Academic/Hospital | 1 | 0 | 1 | 2008 |
57 organizations
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