nevulose
Small moleculeexperimental
Fructose, or fruit sugar, is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. At a commercial scale, fructose is often derived from sugar cane, sugar beets, and maize. Fructose is one of the three dietary monosaccharides, along with glucose and galactose, that are absorbed directly into the bloodstream. A growing body of research suggests that diet high in fructose may be contributing to incidences of obesity, insulin resistance, and diabetes. — NCATS
Clinical trial activity
28 trials · 40 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
0
Phase 3
0
Phase 4
0
Earliest trial started Aug 1, 1995 (NCT00004797)
Timeline
2000s
- Jan 1, 2007
Earliest Phase 1 Sponsor(trial)
Indications
Approved for
Mechanism of action
- Unspecified targetUnclear
unclear
Chemistry & pharmacology
Loading structure…
SMILES
OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O- Mol. weight
- 180.16 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- NCATS6YSS42VSEV ↗
- ChEMBLCHEMBL604608 ↗
Also known as
- d-arabino-2-hexulose
- d-fructopyranose
- d-fructopyranose
- d-fructopyranose
- d-fructopyranose
- d-fructopyranose
- d-fructopyranose
- d-(-)-fructose
- dietade dietary foods
- d-(-)-levulose
- fructose
- fructose
- fructose
- fructose
- fructose
- fructose
- fruit sugar
- levulose
- levulose
- levulose
- nevulose
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03076684 | Early Phase 1 (Phase 1) | Mar 3, 2017 | University of Missouri |
| NCT03067428 | N/A | Jan 31, 2017 | Maastricht University |
| NCT02940184 | N/A | Jun 1, 2016 | University of Copenhagen |
| NCT03173495 | N/A | Jan 10, 2016 | Federal University of Rio Grande do Sul |
| NCT02455726 | N/A | Sep 1, 2015 | University of Brescia |
| NCT02876796 | Phase 1 | Aug 1, 2015 | Gilead Sciences, Nimbus Apollo |
| NCT02891525 | N/A | Mar 1, 2015 | Katholieke Universiteit Leuven |
| NCT02590913 | N/A | Mar 1, 2015 | Zhejiang University |
| NCT02902224 | N/A | Apr 1, 2014 | University of Basel, University of Bern |
| NCT02589613 | N/A | Oct 1, 2013 | University of Basel, University of Bern |
| NCT01866215 | N/A | May 1, 2013 | University of Bern, University of Lausanne |
| NCT02075164 | N/A | May 1, 2013 | Medical University of Vienna, University of Vienna, Wiener Wissenschafts-, Forschungs- und Technologiefonds |
| NCT01713023 | N/A | Mar 1, 2013 | Federal University of Rio de Janeiro, Rio de Janeiro State University |
| NCT01918566 | N/A | Mar 1, 2012 | University of Bern |
| NCT01459406 | N/A | Oct 1, 2011 | University of Nottingham |
| NCT01445730 | N/A | Aug 1, 2011 | Clinical Research Institute HUCH Ltd, Laval University, Lund University, University of Gothenburg, University of Helsinki, University of Naples Frederico II |
| NCT01407627 | N/A | Jul 1, 2011 | University of Calgary |
| NCT02217605 | N/A | Mar 1, 2011 | Biotechnology and Biological Sciences Research Council, Unilever, University of Nottingham |
| NCT01119989 | N/A | May 1, 2010 | University of Bern, University of Lausanne |
| NCT01188083 | N/A | Jun 1, 2009 | Emory University |
Showing 20 of 28 trials
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Organizations
Research & Development (40)
40 organizations
Page 1 / 2