oligofructose
Small moleculeexperimental
Fructooligosaccharides (FOS) also sometimes called oligofructose or oligofructan, are oligosaccharide fructans, used as an alternative sweetener. FOS exhibits sweetness levels between 30 and 50 percent of sugar in commercially prepared syrups. It occurs naturally, and its commercial use emerged in the 1980s in response to demand for healthier and calorie-reduced foods. — Wikipedia
Clinical trial activity
26 trials · 33 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
5
Phase 3
1
Phase 4
1
Earliest trial started Nov 1, 2005 (NCT00164099)
Timeline
Indications
Approved for
Studied for
- Bacteremia · Phase 4
- Cystitis · Phase 4
- Enterocolitis, Pseudomembranous · Phase 4
- Febrile Neutropenia · Phase 2
- Infections · Phase 2
- Influenza, Human · Phase 1
- Insulin Resistance · Phase 3
- Neoplasms · Phase 2
- Neutropenia · Phase 2
- Pediatric Obesity · Phase 3
- Pneumonia · Phase 4
- Renal Insufficiency, Chronic · Phase 1/Phase 2
- Surgical Wound Infection · Phase 4
Mechanism of action
- Unspecified targetSupplementation
supplementation
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaFructooligosaccharide ↗
Also known as
- oligofructose
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07097389 | N/A | Jul 31, 2024 | University of Reading |
| NCT04578652 | Phase 3 | Oct 31, 2020 | University of Alberta |
| NCT04100200 | N/A | Oct 7, 2019 | Illinois Institute of Technology, United States Department of Agriculture |
| NCT04164914 | N/A | Apr 29, 2019 | Universidad Autonoma de Barcelona |
| NCT03482258 | N/A | May 31, 2018 | FrieslandCampina, University of Roehampton |
| NCT04250831 | N/A | Mar 12, 2018 | Roehampton University, University of Roehampton |
| NCT02642172 | N/A | Jan 1, 2016 | Hebrew University |
| NCT02628678 | N/A | Nov 1, 2015 | Kaleido Biosciences |
| NCT02569684 | N/A | Oct 1, 2015 | Norwegian Diabetes Association, Osaka University, University Hospital of North Norway |
| NCT02259465 | N/A | Sep 1, 2014 | University of London, University of Nottingham |
| NCT02232373 | N/A | Aug 1, 2014 | University of London, University of Nottingham |
| NCT02124759 | Phase 2 | Apr 1, 2014 | American Diabetes Association, University of Texas, San Antonio |
| NCT02127125 | Phase 2 | Apr 1, 2014 | American Diabetes Association, University of Texas, San Antonio |
| NCT02353403 | N/A | Jan 31, 2014 | Institut Pasteur, Tereos |
| NCT02352857 | N/A | Oct 31, 2013 | Institut Pasteur, Tereos |
| NCT01963364 | N/A | Oct 1, 2013 | University of Nottingham |
| NCT03517345 | N/A | Apr 22, 2013 | Istanbul University |
| NCT03184376 | N/A | Feb 28, 2012 | University of Calgary |
| NCT01673152 | N/A | Feb 1, 2012 | Medical University of Warsaw, Nutricia |
| NCT01304771 | Phase 1 | Dec 1, 2010 | Mayo Clinic, National Center for Complementary and Integrative Health (NCCIH) |
Showing 20 of 26 trials
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Organizations
Research & Development (33)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of London | Academic/Hospital | 3 | 1 | 1 | 2009 |
| University of Nottingham | Academic/Hospital | 3 | 3 | 1 | 2013 |
| American Diabetes Association | Academic/Hospital | 2 | 0 | 1 | 2014 |
| Institut Pasteur | Academic/Hospital | 2 | 2 | 1 | 2013 |
| Tereos | For profit | 2 | 0 | 1 | 2013 |
| University of Calgary | Academic/Hospital | 2 | 2 | 1 | 2007 |
| University of Roehampton | Academic/Hospital | 2 | 2 | 1 | 2018 |
| University of Texas, San Antonio | Academic/Hospital | 2 | 2 | 1 | 2014 |
| Abecma | For profit | 1 | 0 | 1 | 2010 |
| FrieslandCampina | For profit | 1 | 0 | 1 | 2018 |
| Harvard University | Academic/Hospital | 1 | 1 | 1 | 2005 |
| Hebrew University | Academic/Hospital | 1 | 1 | 1 | 2016 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 1 | 0 | 1 | 2005 |
| Illinois Institute of Technology | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Istanbul University | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Kaleido Biosciences | For profit | 1 | 1 | 1 | 2015 |
| Katholieke Universiteit Leuven | Academic/Hospital | 1 | 1 | 1 | 2006 |
| Mayo Clinic | Academic/Hospital | 1 | 1 | 1 | 2010 |
| Medical University of Warsaw | Academic/Hospital | 1 | 1 | 1 | 2012 |
| National Center for Complementary and Integrative Health (NCCIH) | Government | 1 | 0 | 1 | 2010 |
33 organizations
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