exendin (9-39)
Peptideexperimental
Clinical trial activity
56 trials · 38 clinical orgs · 0 marketing orgs
Phase 1
21
Phase 2
13
Phase 3
3
Phase 4
5
Earliest trial started Feb 1, 1999 (NCT00468091)
Timeline
Indications
Approved for
Studied for
- Alzheimer Disease · Phase 2
- Bariatric Surgery · Phase 2
- Cognitive Dysfunction · Phase 2
- Congenital Hyperinsulinism · Phase 1/Phase 2
- Diabetes Mellitus · Phase 1
- Diabetes Mellitus, Type 2 · Phase 4
- Digestive System Physiological Phenomena · Phase 1
- Drugs, Investigational · Phase 1
- Dyspepsia · Phase 2
- Enteral Nutrition · Phase 1
- Gastrectomy · Early Phase 1
- Gastric Bypass · Phase 1
- Gastric Emptying · Phase 1
- Gastrointestinal Hormones · Phase 1
- Gastrointestinal Motility · Phase 1
- Genetic Predisposition to Disease · Phase 2
- Glucagon-Like Peptide 1 · Phase 1
- Healthy Volunteers · Phase 3
- Hyperglycemia · Phase 1
- Hypoglycemia · Phase 2
- Insulin Secretion · Phase 4
- Obesity · Phase 4
- Pancreatic Diseases · Phase 1
- Prediabetic State · Phase 4
Mechanism of action
- GlucagonANTAGONIST
GCG antagonist
Chemistry & pharmacology
- Multi-specific
- No
Oral
No
Parenteral
No
Topical
No
Also known as
- ex-9
- exendin 3 (heloderma horridum), 1-de-l-histidine-2-de-l-serine-3-de-l-aspartic acid-4-deglycine-5-de-l-threonine-6-de-l-phenylalanine-7-de-l-threonine-8-de-l-serine-
- exendin (9-39)
- exendin (9-39)
- exendin (9-39)
- exendin 9-39
- exendin 9-39
- exendin-(9-39)
- exendin(9-39)
- exendin(9-39) 1200
- exendin(9-39) 300
- exendin(9-39) 600
- exendin(9-39) 900
- exendin (9-39) amide
- exendin(9-39)amide
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06872060 | N/A | Jun 1, 2026 | University of Copenhagen |
| NCT06972407 | Phase 2 | Dec 1, 2025 | Mayo Clinic |
| NCT07224334 | Phase 1 | Nov 30, 2025 | Duke University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
| NCT06967558 | Phase 2 | Nov 1, 2025 | Mayo Clinic |
| NCT04652479 | Phase 2 | Jun 21, 2021 | Eiger BioPharmaceuticals, Stanford University |
| NCT04459338 | Phase 3 | Jan 31, 2021 | Mayo Clinic, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
| NCT04466566 | Phase 3 | Jan 31, 2021 | Mayo Clinic, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
| NCT04466618 | Phase 3 | Dec 31, 2020 | Mayo Clinic, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
| NCT03950245 | N/A | May 31, 2019 | University of Copenhagen |
| NCT03373435 | Phase 2 | Mar 19, 2018 | Eiger BioPharmaceuticals |
| NCT02971631 | N/A | Aug 10, 2017 | University of Cambridge |
| NCT03241303 | N/A | Aug 1, 2017 | University of Copenhagen |
| NCT02844907 | Phase 4 | Aug 1, 2017 | Department of Veteran Affairs, Duke University |
| NCT03246451 | N/A | Jul 1, 2017 | University of Copenhagen |
| NCT03101930 | Phase 4 | May 1, 2017 | American Heart Association, Vanderbilt University |
| NCT02779075 | N/A | Jun 1, 2016 | Mayo Clinic, The Obesity Society |
| NCT02771574 | Phase 2 | May 1, 2016 | Stanford University |
| NCT02550548 | Phase 1 | Apr 21, 2016 | Duke University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
| NCT02762708 | N/A | Mar 1, 2016 | Mayo Clinic |
| NCT02697253 | N/A | Jan 1, 2016 | Columbia University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Showing 20 of 56 trials
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Organizations
Research & Development (38)
38 organizations
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