CDEK
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prolycopene

Botanicalexperimental

Clinical trial activity

36 trials · 41 clinical orgs · 0 marketing orgs

Phase 1
7
Phase 2
19
Phase 3
6
Phase 4
1

Earliest trial started Jun 1, 2000 (NCT00006078)

Timeline

2000s

  1. Jan 1, 2000

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 2004

    Earliest Phase 2 Sponsor(trial)

  3. Jan 1, 2009

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetAntioxidant

    antioxidant

Chemistry & pharmacology

Loading structure…

SMILES

CC(C)=CCC/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C=C(\C)CCC=C(C)C
Mol. weight
536.89 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Achiral Molecule
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • all-trans-lycopene
  • lyc-o-mato
  • lycopene
  • lycopene
  • lycopene
  • lycopene
  • lycopene
  • lycopene
  • lycopene, (13-cis)-isomer
  • lycopene, (7-cis,7'-cis,9-cis,9'-cis)-isomer
  • lycopene, (cis)-isomer
  • lycored
  • lycored
  • lycored
  • prolycopene
  • prolycopene
  • psi,psi-carotene

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03167268Phase 2Aug 3, 2016University of Milan
NCT03203746Phase 1/Phase 2 (Phase 2)Sep 28, 2015Ain Shams University
NCT02714543Phase 3Nov 1, 2013The Oxford Dental College, Hospital and Research Center, Bangalore, India
NCT01949519Phase 1Nov 1, 2013Medical University of South Carolina, National Cancer Institute (NCI), University of South Carolina
NCT02587117Phase 4Feb 1, 2013B.P. Koirala Institute of Health Sciences
NCT01666587N/AAug 1, 2012Thompson Rivers University, University of Essex
NCT01667510Phase 2Aug 1, 2012LycoRed Ltd., Maccabi Healthcare Services, Israel
NCT01665742N/AJan 1, 2012National Children's Research Centre, Ireland, National University of Ireland, The Adelaide and Meath Hospital, Trinity College Dublin
NCT01287182Phase 3May 1, 2011Omicron Pharmaceuticals
NCT01321268N/AMay 1, 2011DSM, Pontifical Catholic University of Rio Grande do Sul
NCT01286909Phase 3Jan 1, 2011Omicron Pharmaceuticals, Rafik Hariri University
NCT01882985Phase 2Dec 1, 2010University of California, Irvine
NCT00905931Phase 2Sep 1, 2010Cambridge Theranostics Ltd, University of Cambridge
NCT01377961N/ASep 1, 2010University of Texas, Galveston
NCT01105338Phase 2/Phase 3 (Phase 3)Aug 1, 2009University of Bristol
NCT01221558Phase 3Jul 1, 2009Yonsei University
NCT00939237Phase 3Jul 1, 2009Cambridge Nutraceuticals Ltd, Cambridge Theranostics Ltd, Harvard University
NCT00637858N/AOct 1, 2008Ben Gurion University, LycoRed Ltd., The S. Daniel Abraham International Center for Health and Nutrition
NCT00844792Phase 2Oct 1, 2008University of Toronto
NCT00669656Phase 2Jul 6, 2008University of Southern California
Showing 20 of 36 trials
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Organizations

Research & Development (41)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Cancer Institute (NCI)Government13332000
University of Illinois at ChicagoAcademic/Hospital7632000
Cambridge Theranostics LtdFor profit2022009
LycoRed Ltd.For profit2122008
National Taiwan UniversityAcademic/Hospital2212004
Omicron PharmaceuticalsFor profit2212011
University of TorontoAcademic/Hospital2212008
Ain Shams UniversityAcademic/Hospital1112015
Ben Gurion UniversityAcademic/Hospital1112008
B.P. Koirala Institute of Health SciencesAcademic/Hospital1112013
Cambridge Nutraceuticals LtdFor profit1012009
College of Dental Sciences, DavangereAcademic/Hospital1012004
College of Dental Sciences, IndiaAcademic/Hospital1112004
DSMFor profit1112011
Harvard UniversityAcademic/Hospital1112009
Maccabi Healthcare Services, IsraelAcademic/Hospital1012012
Mayo ClinicAcademic/Hospital1012004
Medical University of South CarolinaAcademic/Hospital1012013
National Children's Research Centre, IrelandAcademic/Hospital1012012
National University of IrelandAcademic/Hospital1112012
41 organizations
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