CDEK
← Mechanisms of action

DNA

NUCLEIC-ACIDHomo sapiens

Drugs acting on this target (143)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
brostallicinAllosteric antagonistexperimentalSmall moleculeDNA allosteric antagonist
cbl0137Binding agentexperimentalSmall moleculeDNA binding agent
mAb 3E10Binding agentexperimentalmAbDNA
psoralenBinding agentexperimentalSmall moleculeDNA binding agent
4-demethyl-4-cholesteryloxycarbonylpenclomedineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
aroplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
bp-c1Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
briplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
btp-114Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
camidanlumab tesirineCross-linking agentexperimentalmAbDNA cross-linking agent
cis-diamminedichloroplatinumCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
cp-506Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
dianhydrogalactitolCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
dicycloplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
dimethane sulfonateCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
fotemustineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
glufosfamideCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
ifosfamide (ifex)Cross-linking agentapprovedSmall moleculeDNA cross-linking agent
kml-001Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
Laromustine (onrigin)Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
lobaplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
loncastuximab (Zynlonta)Cross-linking agentapprovedmAbDNA cross-linking agent
melphalan (alkeran)Cross-linking agentapprovedSmall moleculeDNA cross-linking agent
methoxyamineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
nanoplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
nc-4016Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
nedaplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
nimustineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
obi-3424Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
opd5Cross-linking agentexperimentalPeptideDNA cross-linking agent
perfosfamide (Pergamid)Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
picoplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
pixuvriCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
platinum acetylacetonateCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
porfiromycinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
pr-104Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
ranimustineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
rovalpituzumab tesirineCross-linking agentexperimentalmAbDNA cross-linking agent
rxdx-107Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
sarmustineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
satraplatinCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
semustineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
sjg-136Cross-linking agentexperimentalSmall moleculeDNA cross-linking agent
tinostamustineCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
treosulfanCross-linking agentapprovedSmall moleculeDNA cross-linking agent
triethylene glycol diglycidyl etherCross-linking agentexperimentalSmall moleculeDNA cross-linking agent
zalypsisCross-linking agentexperimentalAnimal productDNA cross-linking agent
ast-3424DegraderexperimentalSmall moleculeDNA degrader
cantharidin (Ycanth)DegraderapprovedSmall moleculeDNA degrader
genz-644282DegraderexperimentalSmall moleculeDNA degrader
gimatecanDegraderexperimentalSmall moleculeDNA degrader
irofulvenDegraderexperimentalSmall moleculeDNA degrader
4-demethyl-4-cholesteryloxycarbonylpenclomedineDisrupting agentexperimentalSmall moleculeDNA disrupting agent
AspacytarabineDisrupting agentexperimentalSmall moleculeDNA disrupting agent
bisantreneDisrupting agentexperimentalSmall moleculeDNA disrupting agent
brostallicinDisrupting agentexperimentalSmall moleculeDNA disrupting agent
cmd-193Disrupting agentexperimentalmAbDNA disrupting agent
cytidineDisrupting agentexperimentalSmall moleculeDNA disrupting agent
Doxifluridine (furtulon)Disrupting agentexperimentalSmall moleculeDNA disrupting agent
gemtuzumab ozogamicin (mylotarg)Disrupting agentapprovedmAbDNA disrupting agent
glufosfamideDisrupting agentexperimentalSmall moleculeDNA disrupting agent
imgn632Disrupting agentexperimentalmAbDNA disrupting agent
inotuzumab ozogamicin (besponsa)Disrupting agentapprovedmAbDNA disrupting agent
lutetium (177Lu) vipivotide tetraxetan (Pluvicto)Disrupting agentapprovedSmall moleculeDNA disrupting agent
myelobromolDisrupting agentexperimentalSmall moleculeDNA disrupting agent
nimustineDisrupting agentexperimentalSmall moleculeDNA disrupting agent
nuc-1031Disrupting agentexperimentalSmall moleculeDNA disrupting agent
proflavineDisrupting agentexperimentalSmall moleculeDNA disrupting agent
rovalpituzumab tesirineDisrupting agentexperimentalmAbDNA disrupting agent
sodium iodide i-131 (iodotope)Disrupting agentapprovedSmall moleculeDNA disrupting agent
tirapazamineDisrupting agentexperimentalSmall moleculeDNA disrupting agent
tlk286Disrupting agentexperimentalSmall moleculeDNA disrupting agent
ytterbium (169yb) dtpaDisrupting agentapprovedSmall moleculeDNA disrupting agent
dornase alfa (pulmozyme)Hydrolytic enzymeapprovedRecombinant proteinDNA hydrolytic enzyme
cls12311Immunity, desensitizedexperimentalCell therapyDNA immunity, desensitized
altretamine (hexalen)InhibitorapprovedSmall moleculeDNA inhibitor
aminolevulinic acid (levulan)InhibitorapprovedSmall moleculeDNA inhibitor
apaziquoneInhibitorexperimentalSmall moleculeDNA inhibitor
azacitidine (vidaza)InhibitorapprovedSmall moleculeDNA inhibitor
azathioprine (imuran)InhibitorapprovedSmall moleculeDNA inhibitor
bendamustine (treanda)InhibitorapprovedSmall moleculeDNA inhibitor
bleomycin (blenoxane)InhibitorapprovedSmall moleculeDNA inhibitor
broxuridineInhibitorexperimentalSmall moleculeDNA inhibitor
capecitabine (xeloda)InhibitorapprovedSmall moleculeDNA inhibitor
carboplatin (paraplatin)InhibitorapprovedSmall moleculeDNA inhibitor
carmustine (bicnu)InhibitorapprovedSmall moleculeDNA inhibitor
chlorambucil (Leukeran)InhibitorapprovedSmall moleculeDNA inhibitor
cisplatin (platinol)InhibitorapprovedSmall moleculeDNA inhibitor
cladribine (leustatin)InhibitorapprovedSmall moleculeDNA inhibitor
clofarabine (clolar)InhibitorapprovedSmall moleculeDNA inhibitor
cyclophosphamide (cytoxan)InhibitorapprovedSmall moleculeDNA inhibitor
cytarabine (cytosar-u)InhibitorapprovedSmall moleculeDNA inhibitor
dacarbazine (dtic-dome)InhibitorapprovedSmall moleculeDNA inhibitor
daunorubicin (cerubidine)InhibitorapprovedSmall moleculeDNA inhibitor
decitabine (dacogen)InhibitorapprovedSmall moleculeDNA inhibitor
Doxifluridine (furtulon)InhibitorexperimentalSmall moleculeDNA inhibitor
doxorubicin (Doxil)InhibitorapprovedSmall moleculeDNA inhibitor
ecubectedinInhibitorexperimentalSmall moleculeDNA inhibitor
elacytarabineInhibitorexperimentalSmall moleculeDNA inhibitor
epirubicin (ellence)InhibitorapprovedSmall moleculeDNA inhibitor
estramustine (emcyt)InhibitorapprovedSmall moleculeDNA inhibitor
evofosfamideInhibitorexperimentalSmall moleculeDNA inhibitor
fluorouracil (efudex)InhibitorapprovedSmall moleculeDNA inhibitor
Fosgemcitabine (acelarin)InhibitorexperimentalSmall moleculeDNA inhibitor
gemtuzumab ozogamicin (mylotarg)InhibitorapprovedmAbDNA inhibitor
hydroxystilbamidine isetionateInhibitorapprovedSmall moleculeDNA inhibitor
idarubicin (idamycin)InhibitorapprovedSmall moleculeDNA inhibitor
lomustineInhibitorapprovedSmall moleculeDNA inhibitor
mb07133InhibitorexperimentalSmall moleculeDNA inhibitor
mbc-11InhibitorexperimentalSmall moleculeDNA inhibitor
mechlorethamine (mustargen)InhibitorapprovedSmall moleculeDNA inhibitor
melphalan (alkeran)InhibitorapprovedSmall moleculeDNA inhibitor
mercaptopurine (purinethol)InhibitorapprovedSmall moleculeDNA inhibitor
methoxsalenInhibitorapprovedSmall moleculeDNA inhibitor
methyl aminolevulinate (metvixia)InhibitorapprovedSmall moleculeDNA inhibitor
mgi-114InhibitorexperimentalSmall moleculeDNA inhibitor
mitomycin (mutamycin)InhibitorapprovedSmall moleculeDNA inhibitor
mitoxantrone (novantrone)InhibitorapprovedSmall moleculeDNA inhibitor
mm-302InhibitorexperimentalmAbDNA inhibitor
nelarabine (arranon)InhibitorapprovedSmall moleculeDNA inhibitor
pipobroman (vercyte)InhibitorapprovedSmall moleculeDNA inhibitor
plicamycin (mithracin)InhibitorapprovedSmall moleculeDNA inhibitor
porfimer (photofrin)InhibitorapprovedSmall moleculeDNA inhibitor
procarbazine (matulane)InhibitorapprovedSmall moleculeDNA inhibitor
sapacitabineInhibitorexperimentalSmall moleculeDNA inhibitor
streptozotocinInhibitorapprovedSmall moleculeDNA inhibitor
tas-109InhibitorexperimentalSmall moleculeDNA inhibitor
tegafurInhibitorexperimentalSmall moleculeDNA inhibitor
temozolomide (temodar)InhibitorapprovedSmall moleculeDNA inhibitor
tetra-o-methyl nordihydroguaiaretic acidInhibitorexperimentalSmall moleculeDNA inhibitor
tetrahydrouridineInhibitorexperimentalSmall moleculeDNA inhibitor
thiotepaInhibitorapprovedSmall moleculeDNA inhibitor
tioguanine (Lanvis)InhibitorapprovedSmall moleculeDNA inhibitor
trioxsalen (trisoralen)InhibitorapprovedSmall moleculeDNA inhibitor
uracil mustardInhibitorapprovedSmall moleculeDNA inhibitor
valrubicin (valstar)InhibitorapprovedSmall moleculeDNA inhibitor
verteporfin (visudyne)InhibitorapprovedSmall moleculeDNA inhibitor
vosaroxinInhibitorexperimentalSmall moleculeDNA inhibitor
vio-01ModulatorexperimentalNucleic acidDNA modulator
lurbinectedin (Zepzelca)Negative modulatorapprovedSmall moleculeDNA negative modulator
bisantreneOtherexperimentalSmall moleculeDNA
kit for iodinated I-125 albumin (Jeanatope)RadiodepletionapprovedBiologicalDNA radiodepletion
thorium nitrateRadiodepletionmarketedSmall moleculeDNA radiodepletion