CDEK
← All drugs Report issue

cisplatin

Trade name: platinol

Small moleculeapproved

Approved

Dec 19, 1978

There is no available sources on the medical use of platinum iodide. The salt is insoluble. — NCATS

Clinical trial activity

3,539 trials · 1,240 clinical orgs · 13 marketing orgs

Phase 1
692
Phase 2
2833
Phase 3
970
Phase 4
46

Earliest trial started Apr 1, 1988 (NCT00002461)

Timeline

1970s

  1. Dec 19, 1978

    Bristol-Myers — Earliest FDA Approval

  2. Dec 19, 1978

    Hq Speciality Pharma — NDA Secondary Org

  3. Dec 19, 1978

    Bristol-Myers — NDA Organization

1980s

  1. Jan 1, 1988

    Earliest Phase 1 Sponsor(trial)

  2. Jan 1, 1988

    Earliest Phase 2 Sponsor(trial)

1990s

  1. Jan 1, 1990

    Earliest Phase 3 Sponsor(trial)

  2. Jul 16, 1999

    Fresenius — Marketing Organization

2000s

  1. May 16, 2000

    Pharmachemie Bv — Marketing Organization

  2. May 16, 2000

    Teva — Marketing Organization

  3. Nov 7, 2000

    West-Ward Pharmaceutical — Marketing Organization

  4. Nov 7, 2000

    Hikma — Marketing Organization

  5. Nov 14, 2000

    Bedford Pharmaceuticals — Marketing Organization

2010s

  1. Apr 18, 2012

    Mylan — Marketing Organization

  2. Apr 18, 2012

    PHARMOBEDIENT — Marketing Organization

  3. Aug 18, 2015

    Accord Research — Marketing Organization

  4. Mar 17, 2017

    Gland Pharma Ltd — Marketing Organization

2020s

  1. May 10, 2024

    Qilu Pharmaceutical Co., Ltd. — Marketing Organization

Indications

Approved for

Studied for

Mechanism of action

  • DNAINHIBITOR

    DNA inhibitor

Approval history

  • approvedDec 19, 1978

Chemistry & pharmacology

Loading structure…

SMILES

N.N.[Cl-].[Cl-].[Pt++]
Mol. weight
300.051 g/mol
Chirality
Achiral Molecule
Inorganic
Yes
Polymer
No
Delivery
Parenteral
Availability
Prescription Only

Oral

No

Parenteral

Yes

Topical

No

Black box warning

Sources

Also known as

  • cddp
  • cddp
  • ciplatin
  • cis-ddp
  • cis-ddp
  • cis-diamminedichloroplatinum(ii)
  • cis-diamminedichloroplatinum(ii)
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin
  • cisplatin liposomal
  • cisplatinum
  • cisplatinum
  • cis-platinum
  • cis-platinum
  • cis-platinum
  • cis-platinum ii
  • cis-platinum ii
  • liposomal cisplatin
  • nc6004
  • nc 6004
  • nc-6004
  • nc-6004
  • nov-002
  • nov-002
  • platine
  • platine
  • platinol
  • platinol
  • platinol
  • platinol
  • platinum
  • platinum
  • platinum
  • platinum
  • platinum diamminodichloride

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT07281417Phase 2Feb 27, 2026National Cancer Institute (NCI), Ohio State University
NCT07218913Phase 1Feb 4, 2026City of Hope National Medical Center, National Cancer Institute (NCI)
NCT07279935Phase 4Jan 15, 2026AstraZeneca
NCT07276360Phase 2Jan 3, 2026National Institutes of Health (NIH), Uganda Cancer Institute, Varian Medical Systems
NCT07295262Early Phase 1 (Phase 1)Jan 1, 2026Sichuan University
NCT07141771Phase 1/Phase 2 (Phase 2)Dec 31, 2025Chinese Academy of Medical Sciences
NCT07221253Phase 3Dec 31, 2025AstraZeneca
NCT07263919Phase 2Dec 31, 2025Akeso Pharmaceuticals, Inc., People's Liberation Army of China
NCT07268040Phase 2Dec 31, 2025Hengrui Therapeutics, Inc.
NCT07283991Phase 2Dec 30, 2025Jiao Tong University
NCT06724042Phase 1Dec 30, 2025InSilico Medicine Hong Kong Limited
NCT07310784Phase 2Dec 16, 2025Government of China
NCT07139951Phase 2Dec 11, 2025Mayo Clinic
NCT07219212Phase 1Dec 11, 2025Johnson and Johnson
NCT07276399Phase 3Dec 3, 2025—
NCT07214779Phase 3Dec 1, 2025ENGOT Foundation, GOG Foundation, Inc., Incyte
NCT07238569Phase 3Dec 1, 2025Sun Yat-Sen University
NCT07244965Phase 2Dec 1, 2025Zhejiang University
NCT07078604Phase 2Dec 1, 2025Kuni Foundation, University of Washington
NCT07229625Phase 3Nov 30, 2025Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Showing 20 of 3,539 trials
Page 1 / 177

Organizations

Research & Development (1,240)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Cancer Institute (NCI)Government56519641990
Sun Yat-Sen UniversityAcademic/Hospital19015951998
MerckFor profit1176232005
Fudan UniversityAcademic/Hospital1139042006
AstraZenecaFor profit1085952000
Chinese Academy of Medical SciencesAcademic/Hospital1066852002
Eli LillyFor profit997942000
Cornell UniversityAcademic/Hospital937441994
University of Texas at HoustonAcademic/Hospital896241992
Harvard UniversityAcademic/Hospital764941994
Jiao Tong UniversityAcademic/Hospital725551997
RocheFor profit674242001
Bristol-Myers SquibbFor profit652832002
SanofiFor profit623151997
Peking UniversityAcademic/Hospital613752005
People's Liberation Army of ChinaGovernment593242008
European Organisation for Research and Treatment of CancerAcademic/Hospital584931993
Gynecologic Oncology GroupAcademic/Hospital514541992
NRG OncologyAcademic/Hospital51841994
Southwest Oncology GroupAcademic/Hospital512841992
1,240 organizations
Page 1 / 62

Marketing (14)

OrganizationOrg typeRelationshipDate
Accord ResearchFor profitMKTGAug 18, 2015
Bedford PharmaceuticalsFor profitMKTGNov 14, 2000
Bristol-MyersFor profitNDADec 19, 1978
FreseniusFor profitMKTGJul 16, 1999
Gland Pharma LtdFor profitMKTGMar 17, 2017
Gland Pharma LtdFor profitSYNMar 17, 2017
HikmaFor profitMKTGNov 7, 2000
Hq Speciality PharmaFor profitNDA2Dec 19, 1978
MylanFor profitMKTGApr 18, 2012
PHARMOBEDIENTFor profitMKTGApr 18, 2012
Pharmachemie BvFor profitMKTGMay 16, 2000
Qilu Pharmaceutical Co., Ltd.For profitMKTGMay 10, 2024
TevaFor profitMKTGMay 16, 2000
West-Ward PharmaceuticalFor profitMKTGNov 7, 2000