4-demethyl-4-cholesteryloxycarbonylpenclomedine
Small moleculeexperimental
Clinical trial activity
6 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Sep 1, 2010 (NCT01048008)
Timeline
Indications
Mechanism of action
Chemistry & pharmacology
Loading structure…
SMILES
COc1nc(C(Cl)(Cl)Cl)c(Cl)c(OC(=O)O[C@H]2CC[C@@]3(C)C(=CC[C@H]4[C@@H]5CC[C@H]([C@H](C)CCCC(C)C)[C@@]5(C)CC[C@@H]43)C2)c1Cl- Mol. weight
- 724.04 g/mol
- Lipinski Ro5
- 2 violation(s)
- Rule of 3
- No
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4297253 ↗
Also known as
- 4-demethyl-4-cholesteryloxycarbonylpenclomedine
- 4-demethyl-4-cholesteryloxycarbonylpenclomedine
- dm-choc-pen
- dm-choc-pen
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03668847 | Phase 2 | Nov 1, 2018 | DEKK-TEC, Inc., Detroit Clinical Research Center, Tulane University |
| NCT03371004 | Phase 1 | Feb 5, 2016 | DEKK-TEC, Inc., Tulane University |
| NCT02889445 | N/A | Feb 1, 2016 | DEKK-TEC, Inc. |
| NCT02038218 | Phase 2 | Sep 1, 2013 | DEKK-TEC, Inc., Detroit Clinical Research Center, Icahn School of Medicine at Mount Sinai, National Cancer Institute (NCI), Ochsner Health System, Tulane University, University of Texas at Houston |
| NCT01048008 | Phase 1 | Sep 1, 2010 | DEKK-TEC, Inc., National Cancer Institute (NCI), Tulane University |
| NCT01976910 | Phase 1 | Sep 1, 2010 | DEKK-TEC, Inc., National Cancer Institute (NCI), Tulane University |
Showing 6 of 6 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| DEKK-TEC, Inc. | For profit | 6 | 6 | 3 | 2010 |
| Tulane University | Academic/Hospital | 5 | 0 | 2 | 2010 |
| National Cancer Institute (NCI) | Government | 3 | 0 | 2 | 2010 |
| Detroit Clinical Research Center | Academic/Hospital | 2 | 0 | 1 | 2013 |
| Icahn School of Medicine at Mount Sinai | Academic/Hospital | 1 | 0 | 1 | 2013 |
| Ochsner Health System | Academic/Hospital | 1 | 0 | 1 | 2013 |
| University of Texas at Houston | Academic/Hospital | 1 | 0 | 1 | 2013 |
7 organizations
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