bisantrene
Small moleculeexperimental
Clinical trial activity
4 trials · 3 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started Sep 1, 2019 (NCT03820908)
Timeline
Indications
Mechanism of action
Chemistry & pharmacology
Loading structure…
SMILES
C(=N\NC1=NCCN1)\c1c2ccccc2c(/C=N\NC2=NCCN2)c2ccccc12- Mol. weight
- 398.47 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL139554 ↗
- ChEMBLCHEMBL25336 ↗
- ChEMBLCHEMBL1979684 ↗
Also known as
- bisantrene
- bisantrene
- bisantrene dihydrochloride
- bisantrene dihydrochloride
- bisantrene dihydrochloride
- bisantrene hydrochloride
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06815575 | Phase 1 | Apr 2, 2025 | Race Oncology Ltd |
| NCT05456269 | Phase 1 | Jul 31, 2022 | Astex Pharmaceuticals, Inc., Race Oncology Ltd |
| NCT04989335 | Phase 2 | Aug 2, 2021 | Race Oncology Ltd, Tel Aviv University |
| NCT03820908 | Phase 2 | Sep 1, 2019 | Race Oncology Ltd, Tel Aviv University |
Showing 4 of 4 trials
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Organizations
Research & Development (3)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Race Oncology Ltd | For profit | 4 | 2 | 2 | 2019 |
| Tel Aviv University | Academic/Hospital | 2 | 2 | 1 | 2019 |
| Astex Pharmaceuticals, Inc. | For profit | 1 | 0 | 1 | 2022 |
3 organizations
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