← All indications
Mutation
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Subtype terms (23)
More specific conditions that are subtypes of Mutation in the MeSH hierarchy.
- Allelic Imbalance
- Base Pair Mismatch
- Chromosome Aberrations
35 drugs (31 approved, 4 experimental)
- Codon, Nonsense
1 drug experimental
- DNA Repeat Expansion
- Frameshift Mutation
- Gain of Function Mutation
- Gene Amplification
18 drugs (8 approved, 10 experimental)
- Gene Duplication
- Genomic Instability
- Germ-Line Mutation
- INDEL Mutation
- Loss of Function Mutation
- Mutagenesis, Insertional
- Mutation Accumulation
- Mutation, Missense
- Mutation Rate
- Point Mutation
- Sequence Deletion
- Sequence Inversion
- Silent Mutation
- Suppression, Genetic
- Synthetic Lethal Mutations
Drugs by status
Phase 4 trials (2)
Phase 3 trials (56)
- icotinib
- decitabine
- arry-371797
- olaparib
- azd-4547
- azd3759
- talazoparib
- irinotecan
- Leniolisib
- elamipretide
- fulvestrant
- gemcitabine
- fluorouracil
- paclitaxel
- imatinib
- secretin human
- rimabotulinumtoxinB
- niraparib
- osimertinib
- ibrutinib
- pemetrexed
- panitumumab
- ifosfamide
- elacestrant
- carboplatin
- sitagliptin
- arsenic trioxide
- acetylsalicylic acid
- bevacizumab
- cetuximab
- +26 more
Phase 2 trials (219)
- fluorothymidine
- allopurinol
- cladribine
- azacitidine
- aav2-hchm
- abemaciclib
- afatinib
- rucaparib
- anlotinib
- ambroxol
- atezolizumab
- apg-115
- acetylcysteine
- avelumab
- urea
- sorafenib
- venetoclax
- berberine
- binimetinib
- blinatumomab
- brigatinib
- busulfan
- bvd-523
- canakinumab
- cb-839
- cobimetinib
- quizartinib
- crenolanib
- dabrafenib
- deslorelin
- +189 more
Phase 1 trials (83)
- dacomitinib
- axitinib
- dabigatran
- tofersen
- bms-986168
- ds-1001b
- rosuvastatin
- 13c-pyruvate
- idh305
- carbamazepine
- ribociclib
- alisertib
- modified vaccinia virus ankara vaccine expressing p53
- nerofe
- nimodipine
- onalespib
- ipilimumab
- rxdx-105
- fedratinib
- digoxin
- trifluridine
- itraconazole
- cbt-101
- midazolam
- pimasertib
- tipiracil
- mirvetuximab soravtansine
- esomeprazole
- naptumomab estafenatox
- neratinib maleate
- +53 more
Other trials (27)
- metformin
- vitamin d3
- nitroglycerin
- doxycycline
- diindolylmethane
- egg
- n-(4-hydroxyphenyl)all-trans retinamide
- synthetic secretin
- amoxicillin
- lamivudine
- lumacaftor
- memantine
- nitazoxanide
- stiripentol
- triheptanoin
- allogeneic adipose derived mesenchymal stem cell
- autologous bone marrow derived mesenchymal cells
- curcumin
- zidovudine
- clarithromycin
- moxifloxacin
- soybean
- sodium bicarbonate
- omeprazole
- nirogacestat
- qingre liangkou ningxin fang
- formyltetrahydrofolate