org-34517
Small moleculeexperimental
Clinical trial activity
3 trials · 2 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Jul 1, 2004 (NCT00212797)
Timeline
2000s
- Jan 1, 2004
Earliest Phase 2 Sponsor(trial)
Indications
Mechanism of action
- Glucocorticoid receptorANTAGONIST
NR3C1 antagonist
Chemistry & pharmacology
Loading structure…
SMILES
CC#C[C@]1(O)CCC2C3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc4c(c3)OCO4)C[C@@]21C- Mol. weight
- 430.54 g/mol
- Lipinski Ro5
- 1 violation(s)
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL3545391 ↗
Also known as
- org34517
- org 34517
- org 34517
- org 34517
- org-34517
- org-34517
- org-34517
- org-34517
- sch 900636
- sch 900636
- sch-900636
- sch-900636
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT00844922 | Phase 2 | Sep 1, 2005 | Merck |
| NCT00226278 | Phase 2 | Sep 1, 2004 | Cornell University |
| NCT00212797 | Phase 2 | Jul 1, 2004 | Merck |
Showing 3 of 3 trials
Page 1 / 1
Organizations
Research & Development (2)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Merck | For profit | 2 | 2 | 1 | 2004 |
| Cornell University | Academic/Hospital | 1 | 1 | 1 | 2004 |
2 organizations
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