pf-04995274

Small moleculeexperimental

Clinical trial activity

7 trials · 3 clinical orgs · 0 marketing orgs

Phase 1
7
Phase 2
0
Phase 3
0
Phase 4
0

Earliest trial started Apr 1, 2010 (NCT01091272)

Timeline

2010s

  1. Jan 1, 2010

    Earliest Phase 1 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

OC1(CN2CCC(COc3noc4cccc(O[C@@H]5CCOC5)c34)CC2)CCOCC1
Mol. weight
432.52 g/mol
Lipinski Ro5
Pass
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • pf-04995274
  • pf-04995274
  • pf-04995274

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03515733Phase 1May 31, 2018University of Oxford
NCT03516604Phase 1May 16, 2018Medical Research Council, Pfizer, University of Oxford
NCT01345864Phase 1May 1, 2011Pfizer
NCT01193062Phase 1Sep 1, 2010Pfizer
NCT01173757Phase 1Aug 1, 2010Pfizer
NCT01169714Phase 1Aug 1, 2010Pfizer
NCT01091272Phase 1Apr 1, 2010Pfizer
Showing 7 of 7 trials
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Organizations

Research & Development (3)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
PfizerFor profit6512010
University of OxfordAcademic/Hospital2212018
Medical Research CouncilGovernment1012018
3 organizations
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