Bronchopulmonary Dysplasia
A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
Drugs by status
Approved for this indication (1)
Phase 3 trials (23)
- vitamin d3
- methylprednisolone
- urea
- calfactant
- colfosceril palmitate
- beclomethasone
- nitric oxide
- surfactant
- beractant
- spironolactone
- cord blood hematopoietic stem cell
- clarithromycin
- oxygen
- multivitamins
- enterococcus faecium
- sodium chloride
- l-cysteine
- dexamethasone
- fish oil
- lactobacillus reuteri
- lactobacillus rhamnosus
- shp607
- at-100
Phase 2 trials (21)
- montelukast
- procaine benzylpenicillin
- cefotaxime
- ibuprofen
- cc10
- nivolumab
- nitrogen
- myoinositol
- pneumostem
- acetaminophen
- immune globulin (human)
- autologous umbilical cord blood
- umbilical cord mesenchymal stem cells
- fetal mesenchymal stem cells
- palmitic acid
- gentamicin
- sildenafil
- pioglitazone
- sinapultide
- vitamin a
- phosphatidylglycerol
Phase 1 trials (15)
Organizations
Organization Involved with Phase 4 Indications (21)
- Chiesi
- The Gerber Foundation
- Maternite Regionale Universitaire
- Cathay General Hospital
- Chang Gung University
- Chung Shan Medical University
- Federal University of Health Science of Porto Alegre
- Federal University of Rio Grande do Sul
- Oregon Health and Science University
- University of Southern California
- Taipei Medical University
- Taipei Veteran General hospital
- University of Indonesia
- National Taiwan University
- University of Lyon
- Universidad Autonoma de San Luis Potosi
- ARAIRLOR
- China Medical University
- University of Lorraine
- Children's Hospital Los Angeles
- Mackay Medical College
Organization Involved with Phase 3 Indications (79)
- ONY
- Abbott
- Shire
- Mallinckrodt
- National Institutes of Health (NIH)
- National Center for Research Resources (NCRR)
- National Heart, Lung, and Blood Institute (NHLBI)
- University of Pennsylvania
- Hebei University
- Brown University
- Case Western Reserve University
- Harvard University
- Duke University
- Emory University
- Guangdong Women and Children Hospital
- Guangzhou Medical University
- Indiana University
- Institut National de la Santé Et de la Recherche Médicale, France
- Ohio State University
- RTI International
- Semmelweis University
- Stanford University
- Tufts University
- University of Iowa
- University of Kansas
- University of Liverpool
- University of Miami
- University of New Mexico
- University of Nottingham
- University of Ottawa
- +49 more
Organization Involved with Phase 2 Indications (44)
- Clarassance, Inc.
- Windtree Therapeutics
- Medipost Co Ltd.
- The EMMES Corporation
- National Eye Institute (NEI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- Ajou University
- University of Manitoba
- Barzilai Medical Center
- Bnai Zion Medical Center
- Advent Health
- Korea University
- Maadi Military Hospital
- Seoul National University
- University of Florida
- University of Kentucky
- University of Maryland
- University of South Alabama
- University of Toronto
- Yonsei University
- Chongqing Medical University
- East Carolina University
- Stony Brook University
- Tel Aviv University
- University of Ulsan
- Food and Drug Administration
- Emek Medical Center
- Hebrew University
- Rush University
- Laniado Medical Center
- +14 more
Organization Involved with Phase 1 Indications (18)
- United Therapeutics
- Merck
- Xemed LLC
- Children's Hospital of Philadelphia
- New York University
- Universidad Complutense de Madrid
- Vinmec International Hospital
- Vanderbilt University
- Good Samaritan Hospital, Cincinnati
- Pomeranian Medical University
- University of Texas, Galveston
- ADAGP Charitable Foundation
- Fundación de Ayuda a la Investigación sobre la Hipertensión pulmonar
- People's Liberation Army of China
- Ontario Institute for Regenerative Medicine (OIRM)
- Stem Cell Network
- Meridigen Biotech Co., Ltd.
- Universidad Carlos III Madrid
Organization Involved with Other Experimental Indications (10)